Mammography

In this volume, the topics are constructed from a variety of contents: the bases of mammography systems, optimization of screening mammography with reference to evidence-based research, new technologies of image acquisition and its surrounding systems, and case reports with reference to up-to-date multimodality images of breast cancer. Mammography has been lagged in the transition to digital imaging systems because of the necessity of high resolution for diagnosis. However, in the past ten years, technical improvement has resolved the difficulties and boosted new diagnostic systems. We hope that the reader will learn the essentials of mammography and will be forward-looking for the new technologies. We want to express our sincere gratitude and appreciation?to all the co-authors who have contributed their work to this volume

Characterising pattern asymmetry in pigmented skin lesions

Abstract. In clinical diagnosis of pigmented skin lesions asymmetric pigmentation is often indicative of melanoma. This paper describes a method and measures for characterizing lesion symmetry. The estimate of mirror symmetry is computed first for a number of axes at different degrees of rotation with respect to the lesion centre. The statistics of these estimates are the used to assess the overall symmetry. The method is applied to three different lesion representations showing the overall pigmentation, the pigmentation pattern, and the pattern of dermal melanin. The best measure is a 100% sensitive and 96% specific indicator of melanoma on a test set of 33 lesions, with a separate training set consisting of 66 lesions

The Internet of Everything

In the era before IoT, the world wide web, internet, web 2.0 and social media made people’s lives comfortable by providing web services and enabling access personal data irrespective of their location. Further, to save time and improve efficiency, there is a need for machine to machine communication, automation, smart computing and ubiquitous access to personal devices. This need gave birth to the phenomenon of Internet of Things (IoT) and further to the concept of Internet of Everything (IoE)

Nonlinear Parametric and Neural Network Modelling for Medical Image Classification

System identification and artificial neural networks (ANN) are families of algorithms used in systems engineering and machine learning respectively that use structure detection and learning strategies to build models of complex systems by taking advantage of input-output type data. These models play an essential role in science and engineering because they fill the gap in those cases where we know the input-output behaviour of a system, but there is not a mathematical model to understand and predict its changes in future or even prevent threats. In this context, the nonlinear approximation of systems is nowadays very popular since it better describes complex instances. On the other hand, digital image processing is an area of systems engineering that is expanding the analysis dimension level in a variety of real-life problems while it is becoming more attractive and affordable over time. Medicine has made the most of it by supporting important human decision-making processes through computer-aided diagnosis (CAD) systems. This thesis presents three different frameworks for breast cancer detection, with approaches ranging from nonlinear system identification, nonlinear system identification coupled with simple neural networks, to multilayer neural networks. In particular, the nonlinear system identification approaches termed the Nonlinear AutoRegressive with eXogenous inputs (NARX) model and the MultiScales Radial Basis Function (MSRBF) neural networks appear for the first time in image processing. Along with the above contributions takes place the presentation of the Multilayer-Fuzzy Extreme Learning Machine (ML-FELM) neural network for faster training and more accurate image classification. A central research aim is to take advantage of nonlinear system identification and multilayer neural networks to enhance the feature extraction process, while the classification in CAD systems is bolstered. In the case of multilayer neural networks, the extraction is carried throughout stacked autoencoders, a bottleneck network architecture that promotes a data transformation between layers. In the case of nonlinear system identification, the goal is to add flexible models capable of capturing distinctive features from digital images that might be shortly recognised by simpler approaches. The purpose of detecting nonlinearities in digital images is complementary to that of linear models since the goal is to extract features in greater depth, in which both linear and nonlinear elements can be captured. This aim is relevant because, accordingly to previous work cited in the first chapter, not all spatial relationships existing in digital images can be explained appropriately with linear dependencies. Experimental results show that the methodologies based on system identification produced reliable images models with customised mathematical structure. The models came to include nonlinearities in different proportions, depending upon the case under examination. The information about nonlinearity and model structure was used as part of the whole image model. It was found that, in some instances, the models from different clinical classes in the breast cancer detection problem presented a particular structure. For example, NARX models of the malignant class showed higher non-linearity percentage and depended more on exogenous inputs compared to other classes. Regarding classification performance, comparisons of the three new CAD systems with existing methods had variable results. As for the NARX model, its performance was superior in three cases but was overcame in two. However, the comparison must be taken with caution since different databases were used. The MSRBF model was better in 5 out of 6 cases and had superior specificity in all instances, overcoming in 3.5% the closest model in this line. The ML-FELM model was the best in 6 out of 6 cases, although it was defeated in accuracy by 0.6% in one case and specificity in 0.22% in another one

The Internet of Everything

In the era before IoT, the world wide web, internet, web 2.0 and social media made people’s lives comfortable by providing web services and enabling access personal data irrespective of their location. Further, to save time and improve efficiency, there is a need for machine to machine communication, automation, smart computing and ubiquitous access to personal devices. This need gave birth to the phenomenon of Internet of Things (IoT) and further to the concept of Internet of Everything (IoE)