186,333 research outputs found

    PkM Edukasi Organisasi Tim Tanggap Darurat di Area Kerja pada Karyawan PT. Sarana Tirta Alamindo

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    An emergency is an unexpected difficult situation that requires immediate treatment to prevent accidents/fatalities. The work environment has the potential for emergencies such as fires and earthquakes. According to risk identification data, the work environment area must be prepared to face disasters by preparing resources. Support infrastructure facilities and human resources. Support infrastructure facilities and human resources. Prevention efforts to minimize risk are by planning a disaster emergency response system. Emergency response unit is a work unit specially formed to deal with emergency situations in the workplace. Emergency response teams work quickly to deal with all disaster events quickly, precisely, and accurately and to reduce the incidence of casualties and losses due to disaster events. Implementation of community service activities for employees of PT. Sarana Tirta Alamindo provides participants with an understanding of emergency response so that they are able to plan emergency response preparedness in the work area. The results of the emergency response socialization activity in the work area, employees understand the importance of being ready for emergency response, through training and discussion all must be familiar and able to apply in their work area emergency response conditions and the importance of support from company leaders to form an emergency response team that works and is directly responsible for handling the situation. work area emergency.An emergency is an unexpected difficult situation that requires immediate treatment to prevent accidents/fatalities. The work environment has the potential for emergencies such as fires and earthquakes. According to risk identification data, the work environment area must be prepared to face disasters by preparing resources. Support infrastructure facilities and human resources. Support infrastructure facilities and human resources. Prevention efforts to minimize risk are by planning a disaster emergency response system. Emergency response unit is a work unit specially formed to deal with emergency situations in the workplace. Emergency response teams work quickly to deal with all disaster events quickly, precisely, and accurately and to reduce the incidence of casualties and losses due to disaster events. Implementation of community service activities for employees of PT. Sarana Tirta Alamindo provides participants with an understanding of emergency response so that they are able to plan emergency response preparedness in the work area. The results of the emergency response socialization activity in the work area, employees understand the importance of being ready for emergency response, through training and discussion all must be familiar and able to apply in their work area emergency response conditions and the importance of support from company leaders to form an emergency response team that works and is directly responsible for handling the situation. work area emergency

    Nephropathia epidemica and Puumala virus occurrence in relation to bank vole (Clethrionomys glareolus) dynamics and environmental factors in northern Sweden

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    The objectives of the thesis were to investigate the spatio-temporal patterns of nephropathia epidemica (NE) in humans and Puumala virus (PUU) occurrence in relation to bank vole (Clethrionomys glareolus) dynamics and environmental factors in a region of high incidence of NE in northern Sweden. Nephropathia epidemica is a mild form of hemorrhagic fever with renal syndrome, and in northern Sweden the most prevailing serious febrile viral infection, second to influenza. All serologically confirmed NE cases during 1991-2001 in the four northernmost counties (n = 2,468) were used to establish spatio-temporal patterns of the occurrence of the human disease. Within the study region, the bank voles show marked population fluctuations with 3-4 yr cycles and the incidence of NE has a temporal component strongly correlated to annual numbers of bank voles in autumn. People living in rural dwellings near coastal areas were abundant among notified cases and middle-aged males were over-represented. The patients were often infected in autumn when engaged in activities such as handling of fire wood, gardening or hay-handling near man-made rodent refugia or cleaning/redecorating within one. A proportion of these patients, confident about site of PUU exposure, were used to establish field sites in two separate studies. Firstly a five year study (1995-1999) at six sites spanning a bank vole population cycle, and secondly a spatially extensive study at 32 sites was conducted in autumn 1998. Densities, fluctuations and demography of vole populations differ between sites of known occurrence of NE were compared to random forest sites. Five years of repeated biannual sampling revealed that case sites harbored more bank voles than random forest sites, in particular during population peaks. For the individual bank voles, the probability of PUU infection was significantly higher in population peak year, increased with age and was higher for males than for females. In the spatially extended study, it was found that in particular environmental characteristics associated with old-growth moist forests (i.e. Alectoria spp., Picea abies, fallen wood and Vaccinium myrtillus) were associated with high bank vole numbers and numbers of PUU infected bank voles. This implies that success in circulation and persistence of PUU within local bank vole populations is strongly influenced by the local environments. In future modeling of PUU transmission, influence of bank vole demography and environmental factors should be useful on establishing risk assessments and identifying areas of particular risk of PUU exposure

    A mathematical model of a tilt-wing aircraft for piloted simulation

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    A mathematical model of a tilt-wing aircraft that was used in a piloted, six-degree-of-freedom flight simulation application is described. Two types of control systems developed for the math model are discussed: a conventional, programmed-flap wing-tilt control system and a geared-flap wing-tilt control system. The primary objective was to develop the capability to study tilt-wing aircraft. Experienced Tilt-wing pilots subjectively evaluated the model using programmed-flap control to assess the quality of the simulation. The math model was then applied to study geared-flap control to investigate the possibility of eliminating the need for auxilary pitch-control devices (such as the horizontal tail rotor or tail jet used in earlier tilt-wing designs). This investigation was performed in the moving-base simulation environment, and the vehicle responses with programmed-flap and geared-flap control were compared. The results of the evaluation of the math model are discussed

    Applying refinement to the use of mice and rats in rheumatoid arthritis research

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    Rheumatoid arthritis (RA) is a painful, chronic disorder and there is currently an unmet need for effective therapies that will benefit a wide range of patients. The research and development process for therapies and treatments currently involves in vivo studies, which have the potential to cause discomfort, pain or distress. This Working Group report focuses on identifying causes of suffering within commonly used mouse and rat ‘models’ of RA, describing practical refinements to help reduce suffering and improve welfare without compromising the scientific objectives. The report also discusses other, relevant topics including identifying and minimising sources of variation within in vivo RA studies, the potential to provide pain relief including analgesia, welfare assessment, humane endpoints, reporting standards and the potential to replace animals in RA research

    Are there functional consequences of a reduction in selenium intake in UK subjects?

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    Dietary Se levels in the UK have fallen over the last 20 years and recent surveys indicate that average Se intakes are 30-40 microg/d, which is well below the current UK reference nutrient intake for adult men (75 microg/d) or women (60 microg/d). Functional consequences of this decline have not been recognised, although epidemiological data suggest it may contribute to increased risk of infections and incidence of some cancers. Previous data have indicated that biochemical changes in Se-dependent proteins occur in otherwise healthy UK subjects given small Se supplements. The current studies have focused on the effect of small Se supplements on the immune response since there is evidence of specific interactions between Se intake and viral replication, and since the potential anti-cancer effects of Se may be mediated by non-antioxidant effects of Se such as changes in immune function. Data indicate that subjects given small Se supplements (50 or 100 microg Se/d) have changes in the activity of Se-dependent enzymes and evidence of improved immune function and clearance of an administered live attenuated virus in the form of poliovirus vaccine. Responses of individual subjects to Se supplements are variable, and current work is evaluating potential explanations for this variability, including genetic variability and pre-existing Se status

    IBIS/PICsIT in-flight performances

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    PICsIT (Pixellated Imaging CaeSium Iodide Telescope) is the high energy detector of the IBIS telescope on-board the INTEGRAL satellite. PICsIT operates in the gamma-ray energy range between 175 keV and 10 MeV, with a typical energy resolution of 10% at 1 MeV, and an angular resolution of 12 arcmin within a \~100 square degree field of view, with the possibility to locate intense point sources in the MeV region at the few arcmin level. PICsIT is based upon a modular array of 4096 independent CsI(Tl) pixels, ~0.70 cm^2 in cross-section and 3 cm thick. In this work, the PICsIT on-board data handling and science operative modes are described. This work presents the in-flight performances in terms of background count spectra, sensitivity limit, and imaging capabilities.Comment: 8 pages, 4 figures. Accepted for publication on A&A, special issue on First Science with INTEGRA

    Establishing an Internet Based Paediatric Cancer Registration and Communication System for the Hungarian Paediatric Oncology Network

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    Cancer registration has developed in Europe over the last 50 years, and in the last decade intensive joint activities between the European Cancer Registries, in response to the need of pan-European harmonization of registration practices, have taken place. The Hungarian Paediatric Cancer Registry has been functioning as the database of the Hungarian Paediatric Oncology Network since 1971, aiming to follow the incidence and the treatment efficacy of malignant diseases.The goals of this globally unique open source information system are the following: 1) to raise the quality of the registration system to the European level by developing an Internet-based registration and communication system, modernizing the database, establishing automatic statistical analyses and adding an Internet website, 2) to support clinical epidemiological studies that we conduct with international collaborators on detailed analyses of the characteristics of patients and their diseases, evaluation of new diagnostic and therapeutic methods, prevention programs, and long-term quality of life and side effects.The benefits of the development of the Internet-based registration and communication system are as follows: a) introduction of an Internet-based case reporting system, b) modernization of the registry database according to international recommendations, c) automatic statistical summaries, encrypted mail systems, document repository, d) application of data security and privacy standards, e) establishment of a website and compilation of educational materials.The overall objective of this scientific project is to contribute towards the improvement of cancer prevention and cancer care for the benefit of the public in general and of cancer patients in particular

    Gamma Ray Large Area Space Telescope (GLAST) Balloon Flight Data Handling Overview

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    The GLAST Balloon Flight Engineering Model (BFEM) represents one of 16 towers that constitute the Large Area Telescope (LAT), a high-energy (>20 MeV) gamma-ray pair-production telescope being built by an international partnership of astrophysicists and particle physicists for a satellite launch in 2006. The prototype tower consists of a Pb/Si pair-conversion tracker (TKR), a CsI hodoscopic calorimeter (CAL), an anti-coincidence detector (ACD) and an autonomous data acquisition system (DAQ). The self-triggering capabilities and performance of the detector elements have been previously characterized using positron, photon and hadron beams. External target scintillators were placed above the instrument to act as sources of hadronic showers. This paper provides a comprehensive description of the BFEM data-reduction process, from receipt of the flight data from telemetry through event reconstruction and background rejection cuts. The goals of the ground analysis presented here are to verify the functioning of the instrument and to validate the reconstruction software and the background-rejection scheme.Comment: 5 pages, 4 figures, to be published in IEEE Transacations on Nuclear Science, August 200

    A modular approach for assessing the effect of radiation environments on man in operational systems. The radiobiological vulnerability of man during task performance

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    A modular approach for assessing the affects of radiation environments on man in operational systems has been developed. The feasibility of the model has been proved and the practicality has been assessed. It has been applied to one operational system to date and information obtained has been submitted to systems analysts and mission planners for the assessment of man's vulnerability and impact on systems survivability. In addition, the model has been developed so that the radiobiological data can be input to a sophisticated man-machine interface model to properly relate the radiobiological stress with other mission stresses including the effects of a degraded system
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