The Little W-Net That Could: State-of-the-Art Retinal Vessel Segmentation with Minimalistic Models

The segmentation of the retinal vasculature from eye fundus images represents one of the most fundamental tasks in retinal image analysis. Over recent years, increasingly complex approaches based on sophisticated Convolutional Neural Network architectures have been slowly pushing performance on well-established benchmark datasets. In this paper, we take a step back and analyze the real need of such complexity. Specifically, we demonstrate that a minimalistic version of a standard U-Net with several orders of magnitude less parameters, carefully trained and rigorously evaluated, closely approximates the performance of current best techniques. In addition, we propose a simple extension, dubbed W-Net, which reaches outstanding performance on several popular datasets, still using orders of magnitude less learnable weights than any previously published approach. Furthermore, we provide the most comprehensive cross-dataset performance analysis to date, involving up to 10 different databases. Our analysis demonstrates that the retinal vessel segmentation problem is far from solved when considering test images that differ substantially from the training data, and that this task represents an ideal scenario for the exploration of domain adaptation techniques. In this context, we experiment with a simple self-labeling strategy that allows us to moderately enhance cross-dataset performance, indicating that there is still much room for improvement in this area. Finally, we also test our approach on the Artery/Vein segmentation problem, where we again achieve results well-aligned with the state-of-the-art, at a fraction of the model complexity in recent literature. All the code to reproduce the results in this paper is released

3D Matting: A Soft Segmentation Method Applied in Computed Tomography

Three-dimensional (3D) images, such as CT, MRI, and PET, are common in medical imaging applications and important in clinical diagnosis. Semantic ambiguity is a typical feature of many medical image labels. It can be caused by many factors, such as the imaging properties, pathological anatomy, and the weak representation of the binary masks, which brings challenges to accurate 3D segmentation. In 2D medical images, using soft masks instead of binary masks generated by image matting to characterize lesions can provide rich semantic information, describe the structural characteristics of lesions more comprehensively, and thus benefit the subsequent diagnoses and analyses. In this work, we introduce image matting into the 3D scenes to describe the lesions in 3D medical images. The study of image matting in 3D modality is limited, and there is no high-quality annotated dataset related to 3D matting, therefore slowing down the development of data-driven deep-learning-based methods. To address this issue, we constructed the first 3D medical matting dataset and convincingly verified the validity of the dataset through quality control and downstream experiments in lung nodules classification. We then adapt the four selected state-of-the-art 2D image matting algorithms to 3D scenes and further customize the methods for CT images. Also, we propose the first end-to-end deep 3D matting network and implement a solid 3D medical image matting benchmark, which will be released to encourage further research.Comment: 12 pages, 7 figure