Aspects of sustainability and design engineering for the production of interconnected smart food packaging

In the present work, the problem of food wastage and the concept of sustainability are studied. An analysis of Life Cycle Assessment as a tool and of the innovative concept of Cradle to Cradle is also carried out, together with an exhaustive comparison of these two approaches. Based on these concepts, an integrated methodology is proposed for the design of interconnected smart products. The smart packaging systems currently available are studied theoretically and a practical case is analysed using the proposed methodology through the design and Life Cycle Assessment of a smart interconnected container that is able to detect the ethylene emitted by climacteric fruit, thereby minimizing food wastage. For the case under study, a major impact is observed of the selected plastics in the resources category, and of the smart system in the human health category

Laser Based Mid-Infrared Spectroscopic Imaging – Exploring a Novel Method for Application in Cancer Diagnosis

A number of biomedical studies have shown that mid-infrared spectroscopic images can provide both morphological and biochemical information that can be used for the diagnosis of cancer. Whilst this technique has shown great potential it has yet to be employed by the medical profession. By replacing the conventional broadband thermal source employed in modern FTIR spectrometers with high-brightness, broadly tuneable laser based sources (QCLs and OPGs) we aim to solve one of the main obstacles to the transfer of this technology to the medical arena; namely poor signal to noise ratios at high spatial resolutions and short image acquisition times. In this thesis we take the first steps towards developing the optimum experimental configuration, the data processing algorithms and the spectroscopic image contrast and enhancement methods needed to utilise these high intensity laser based sources. We show that a QCL system is better suited to providing numerical absorbance values (biochemical information) than an OPG system primarily due to the QCL pulse stability. We also discuss practical protocols for the application of spectroscopic imaging to cancer diagnosis and present our spectroscopic imaging results from our laser based spectroscopic imaging experiments of oesophageal cancer tissue