Robust Modular Feature-Based Terrain-Aided Visual Navigation and Mapping

The visual feature-based Terrain-Aided Navigation (TAN) system presented in this thesis addresses the problem of constraining inertial drift introduced into the location estimate of Unmanned Aerial Vehicles (UAVs) in GPS-denied environment. The presented TAN system utilises salient visual features representing semantic or human-interpretable objects (roads, forest and water boundaries) from onboard aerial imagery and associates them to a database of reference features created a-priori, through application of the same feature detection algorithms to satellite imagery. Correlation of the detected features with the reference features via a series of the robust data association steps allows a localisation solution to be achieved with a finite absolute bound precision defined by the certainty of the reference dataset. The feature-based Visual Navigation System (VNS) presented in this thesis was originally developed for a navigation application using simulated multi-year satellite image datasets. The extension of the system application into the mapping domain, in turn, has been based on the real (not simulated) flight data and imagery. In the mapping study the full potential of the system, being a versatile tool for enhancing the accuracy of the information derived from the aerial imagery has been demonstrated. Not only have the visual features, such as road networks, shorelines and water bodies, been used to obtain a position ’fix’, they have also been used in reverse for accurate mapping of vehicles detected on the roads into an inertial space with improved precision. Combined correction of the geo-coding errors and improved aircraft localisation formed a robust solution to the defense mapping application. A system of the proposed design will provide a complete independent navigation solution to an autonomous UAV and additionally give it object tracking capability

Statistical assessment on Non-cooperative Target Recognition using the Neyman-Pearson statistical test

Electromagnetic simulations of a X-target were performed in order to obtain its Radar Cross Section (RCS) for several positions and frequencies. The software used is the CST MWS©. A 1 : 5 scale model of the proposed aircraft was created in CATIA© V5 R19 and imported directly into the CST MWS© environment. Simulations on the X-band were made with a variable mesh size due to a considerable wavelength variation. It is intended to evaluate the Neyman-Pearson (NP) simple hypothesis test performance by analyzing its Receiver Operating Characteristics (ROCs) for two different radar detection scenarios - a Radar Absorbent Material (RAM) coated model, and a Perfect Electric Conductor (PEC) model for recognition purposes. In parallel the radar range equation is used to estimate the maximum range detection for the simulated RAM coated cases to compare their shielding effectiveness (SE) and its consequent impact on recognition. The AN/APG-68(V)9’s airborne radar specifications were used to compute these ranges and to simulate an airborne hostile interception for a Non-Cooperative Target Recognition (NCTR) environment. Statistical results showed weak recognition performances using the Neyman-Pearson (NP) statistical test. Nevertheless, good RCS reductions for most of the simulated positions were obtained reflecting in a 50:9% maximum range detection gain for the PAniCo RAM coating, abiding with experimental results taken from the reviewed literature. The best SE was verified for the PAniCo and CFC-Fe RAMs.Simulações electromagnéticas do alvo foram realizadas de modo a obter a assinatura radar (RCS) para várias posições e frequências. O software utilizado é o CST MWS©. O modelo proposto à escala 1:5 foi modelado em CATIA© V5 R19 e importado diretamente para o ambiente de trabalho CST MWS©. Foram efectuadas simulações na banda X com uma malha de tamanho variável devido à considerável variação do comprimento de onda. Pretende-se avaliar estatisticamente o teste de decisão simples de Neyman-Pearson (NP), analisando as Características de Operação do Receptor (ROCs) para dois cenários de detecção distintos - um modelo revestido com material absorvente (RAM), e outro sendo um condutor perfeito (PEC) para fins de detecção. Em paralelo, a equação de alcance para radares foi usada para estimar o alcance máximo de detecção para ambos os casos de modo a comparar a eficiência de blindagem electromagnética (SE) entre os diferentes revestimentos. As especificações do radar AN/APG-68(V)9 do F-16 foram usadas para calcular os alcances para cada material, simulando uma intercepção hostil num ambiente de reconhecimento de alvos não-cooperativos (NCTR). Os resultados mostram performances de detecção fracas usando o teste de decisão simples de Neyman-Pearson como detector e uma boa redução de RCS para todas as posições na gama de frequências selecionada. Um ganho de alcance de detecção máximo 50:9 % foi obtido para o RAM PAniCo, estando de acordo com os resultados experimentais da bibliografia estudada. Já a melhor SE foi verificada para o RAM CFC-Fe e PAniCo

Radar Technology

In this book “Radar Technology”, the chapters are divided into four main topic areas: Topic area 1: “Radar Systems” consists of chapters which treat whole radar systems, environment and target functional chain. Topic area 2: “Radar Applications” shows various applications of radar systems, including meteorological radars, ground penetrating radars and glaciology. Topic area 3: “Radar Functional Chain and Signal Processing” describes several aspects of the radar signal processing. From parameter extraction, target detection over tracking and classification technologies. Topic area 4: “Radar Subsystems and Components” consists of design technology of radar subsystem components like antenna design or waveform design

Development of a light-based driver assistance system

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WNT-DEPENDENT REGENERATIVE FUNCTION IS INDUCED IN LEUKEMIA-INITIATING AC133BRIGHT CELLS

The Cancer Stem Cell model supported the notion that leukemia was initiated and maintained in vivo by a small fraction of leukemia-initiating cells (LICs). Previous studies have suggested the involvement of Wnt signaling pathway in Acute Myeloid Leukemia (AML) by the ability to sustain the development of LICs. A novel hematopoietic stem and progenitor cell marker, monoclonal antibody AC133, recognizes the CD34bright CD38- subset of human acute myeloid leukemia cells, suggesting that it may be an early marker for the LICs. During the first part of my phD program we previously evaluated the ability of leukemic AC133+ fraction, to perform engraftment following to xenotransplantation in immunodeficient mouse model Rag2-/-\u3b3c-/-. The results showed that the surface marker AC133 is able to enrich for the cell fraction that contains the LICs. In consideration of our previously reported data, derived from the expression profiling analysis performed in normal (n=10) and leukemic (n=33) human long-term reconstituting AC133+ cells, we revealed that the ligand-dependent Wnt signaling is induced in AML through a diffuse expression and release of WNT10B, a hematopoietic stem cells regenerative-associated molecule. In situ detection performed on bone marrow biopsies of AML patients, showed the activation of the Wnt pathway, through the concomitant presence of the ligand WNT10B and of the active dephosphorylated \u3b2-catenin form, suggesting an autocrine / paracrine-type ligand-dependent activation mechanism. In consideration of the link between hematopoietic regeneration and developmental signaling, we transplanted primary AC133+ AML A46 cells into developing zebrafish. This biosensor model revealed the formation of ectopic structures by activation of dorsal organizer markers that act downstream of the Wnt pathway. These results suggested that the misappropriating Wnt associated functions can promote pathological stem cell-like regeneration responsiveness. The analyses performed in situ retained information on the cellular localization, enabling determination of the activity status of individual cells and allowing the tumor environment view. Taking this issue into consideration, during the second part of my phD program, I set up the application of a new in situ method for localized detection and genotyping of individual transcripts directly in cells and tissues. The mRNA in situ detection technique is based on padlock probes ligation and target priming rolling circle amplification allowing the single nucleotide resolution in heterogenous tissues. The mRNA in situ detection performed on bone marrow biopsies derived from AML patients, showed a diffuse localization pattern of WNT10B molecule in the tissue. Conversely, only the AC133bright cell population shows the Wnt signaling activation signature represented by the cytoplasmatic accumulation and nuclear translocation of the active form of \u3b2-catenin. In spite of this, we previously evidenced that the regenerative function of WNT signaling pathway is defined by the up-regulation of WNT10B, WNT10A, WNT2B and WNT6 loci, we identified the WNT10B as a major locus associated with the regenerative function and over-expressed by all AML patients. By the molecular evaluation of the WNT10B transcript, we isolated an aberrant splicing variant (WNT10BIVS1), that identify Non Core-Binding Factor Leukemia (NCBFL) class and whose potential role is discussed. Moreover, we demonstrate that the function of "leukemia stem cell", present in the cell population enriched for the marker AC133bright, is strictly related to regenerative function associated with WNT signaling, defining the key role of WNT10B ligand as a specific molecular marker for leuchemogenesis. This thesis defines the new suitable approaches to characterize the leukemia-initiating cells (LICs) and suggest the role of WNT10B as a new suitable target for AML

Inferring differences between networks using Bayesian exponential random graph models

The goal of many neuroimaging studies is to better understand how the functional connectivity structure of the brain changes with a given phenotype such as age. Functional connectivity can be characterised as a network, with nodes corresponding to brain regions and edges corresponding to statistical dependencies between the respective regional time series of activity. A typical neuroimaging dataset will thus consist of one or more networks for each individual in the study. Most statistical network models, however, were originally proposed to describe a single underlying relational structure such as friendships between individuals or hyperlinks between web pages. As a result, the development of these models has largely been restricted to the single network case. While one could in principle fit a single network model to each individual separately, it is not always straightforward to combine these individual results into a single group result. In the first half of the thesis, we propose a multilevel framework for populations of networks based on exponential random graph models. By pooling information across the individual networks, this framework provides a principled approach to characterise the relational structure for an entire population. We use the framework to assess group-level variations in functional connectivity, providing a method for the inference of differences in the topological structure between groups of networks. Our motivation stems from the Cam-CAN project, a neuroimaging study on healthy ageing. Using this dataset, we illustrate how our method can be used to detect differences in functional connectivity between a group of young individuals and a group of old individuals. In the second half of the thesis, we shift our focus to dynamic functional connectivity (dFC). Recent studies have found that using static measures may average over informative fluctuations in functional connectivity. Several methods have been developed to measure dFC in functional magnetic resonance imaging (fMRI) data. However, spurious group differences in measured dFC may be caused by other sources of heterogeneity between people. We use a generic simulation framework for fMRI data to investigate the effect of such heterogeneity on estimates of dFC and find that, despite no differences in true dFC, individual differences in measured dFC can result from other (non-dynamic) features of the data. We then add a natural and novel extension to our multilevel framework by inserting time windows as an intermediate level between time points and subjects. Using magnetoencephalography data from the Cam-CAN study, we apply our method to detect differences in time-varying connectivity between a young group and an old group

Radar satellite imagery for humanitarian response. Bridging the gap between technology and application

This work deals with radar satellite imagery and its potential to assist of humanitarian operations. As the number of displaced people annually increases, both hosting countries and relief organizations face new challenges which are often related to unclear situations and lack of information on the number and location of people in need, as well as their environments. It was demonstrated in numerous studies that methods of earth observation can deliver this important information for the management of crises, the organization of refugee camps, and the mapping of environmental resources and natural hazards. However, most of these studies make use of -high-resolution optical imagery, while the role of radar satellites is widely neglected. At the same time, radar sensors have characteristics which make them highly suitable for humanitarian response, their potential to capture images through cloud cover and at night in the first place. Consequently, they potentially allow quicker response in cases of emergencies than optical imagery. This work demonstrates the currently unused potential of radar imagery for the assistance of humanitarian operations by case studies which cover the information needs of specific emergency situations. They are thematically grouped into topics related to population, natural hazards and the environment. Furthermore, the case studies address different levels of scientific objectives: The main intention is the development of innovative techniques of digital image processing and geospatial analysis as an answer on the identified existing research gaps. For this reason, novel approaches are presented on the mapping of refugee camps and urban areas, the allocation of biomass and environmental impact assessment. Secondly, existing methods developed for radar imagery are applied, refined, or adapted to specifically demonstrate their benefit in a humanitarian context. This is done for the monitoring of camp growth, the assessment of damages in cities affected by civil war, and the derivation of areas vulnerable to flooding or sea-surface changes. Lastly, to foster the integration of radar images into existing operational workflows of humanitarian data analysis, technically simple and easily-adaptable approaches are suggested for the mapping of rural areas for vaccination campaigns, the identification of changes within and around refugee camps, and the assessment of suitable locations for groundwater drillings. While the studies provide different levels of technical complexity and novelty, they all show that radar imagery can largely contribute to the provision of a variety of information which is required to make solid decisions and to effectively provide help in humanitarian operations. This work furthermore demonstrates that radar images are more than just an alternative image source for areas heavily affected by cloud cover. In fact, what makes them valuable is their information content regarding the characteristics of surfaces, such as shape, orientation, roughness, size, height, moisture, or conductivity. All these give decisive insights about man-made and natural environments in emergency situations and cannot be provided by optical images Finally, the findings of the case studies are put into a larger context, discussing the observed potential and limitations of the presented approaches. The major challenges are summarized which need be addressed to make radar imagery more useful in humanitarian operations in the context of upcoming technical developments. New radar satellites and technological progress in the fields of machine learning and cloud computing will bring new opportunities. At the same time, this work demonstrated the large need for further research, as well as for the collaboration and transfer of knowledge and experiences between scientists, users and relief workers in the field. It is the first extensive scientific compilation of this topic and the first step for a sustainable integration of radar imagery into operational frameworks to assist humanitarian work and to contribute to a more efficient provision of help to those in need.Die vorliegende Arbeit beschäftigt sich mit bildgebenden Radarsatelliten und ihrem potenziellen Beitrag zur Unterstützung humanitärer Einsätze. Die jährlich zunehmende Zahl an vertriebenen oder geflüchteten Menschen stellt sowohl Aufnahmeländer als auch humanitäre Organisationen vor große Herausforderungen, da sie oft mit unübersichtlichen Verhältnissen konfrontiert sind. Effektives Krisenmanagement, die Planung und Versorgung von Flüchtlingslagern, sowie der Schutz der betroffenen Menschen erfordern jedoch verlässliche Angaben über Anzahl und Aufenthaltsort der Geflüchteten und ihrer natürlichen Umwelt. Die Bereitstellung dieser Informationen durch Satellitenbilder wurde bereits in zahlreichen Studien aufgezeigt. Sie beruhen in der Regel auf hochaufgelösten optischen Aufnahmen, während bildgebende Radarsatelliten bisher kaum Anwendung finden. Dabei verfügen gerade Radarsatelliten über Eigenschaften, die hilfreich für humanitäre Einsätze sein können, allen voran ihre Unabhängigkeit von Bewölkung oder Tageslicht. Dadurch ermöglichen sie in Krisenfällen verglichen mit optischen Satelliten eine schnellere Reaktion. Diese Arbeit zeigt das derzeit noch ungenutzte Potenzial von Radardaten zur Unterstützung humanitärer Arbeit anhand von Fallstudien auf, in denen konkrete Informationen für ausgewählte Krisensituationen bereitgestellt werden. Sie sind in die Themenbereiche Bevölkerung, Naturgefahren und Ressourcen aufgeteilt, adressieren jedoch unterschiedliche wissenschaftliche Ansprüche: Der Hauptfokus der Arbeit liegt auf der Entwicklung von innovativen Methoden zur Verarbeitung von Radarbildern und räumlichen Daten als Antwort auf den identifizierten Forschungsbedarf in diesem Gebiet. Dies wird anhand der Kartierung von Flüchtlingslagern zur Abschätzung ihrer Bevölkerung, zur Bestimmung von Biomasse, sowie zur Ermittlung des Umwelteinflusses von Flüchtlingslagern aufgezeigt. Darüber hinaus werden existierende oder erprobte Ansätze für die Anwendung im humanitären Kontext angepasst oder weiterentwickelt. Dies erfolgt im Rahmen von Fallstudien zur Dynamik von Flüchtlingslagern, zur Ermittlung von Schäden an Gebäuden in Kriegsgebieten, sowie zur Erkennung von Risiken durch Überflutung. Zuletzt soll die Integration von Radardaten in bereits existierende Abläufe oder Arbeitsroutinen in der humanitären Hilfe anhand technisch vergleichsweise einfacher Ansätze vorgestellt und angeregt werden. Als Beispiele dienen hier die radargestützte Kartierung von entlegenen Gebieten zur Unterstützung von Impfkampagnen, die Identifizierung von Veränderungen in Flüchtlingslagern, sowie die Auswahl geeigneter Standorte zur Grundwasserentnahme. Obwohl sich die Fallstudien hinsichtlich ihres Innovations- und Komplexitätsgrads unterscheiden, zeigen sie alle den Mehrwert von Radardaten für die Bereitstellung von Informationen, um schnelle und fundierte Planungsentscheidungen zu unterstützen. Darüber hinaus wird in dieser Arbeit deutlich, dass Radardaten für humanitäre Zwecke mehr als nur eine Alternative in stark bewölkten Gebieten sind. Durch ihren Informationsgehalt zur Beschaffenheit von Oberflächen, beispielsweise hinsichtlich ihrer Rauigkeit, Feuchte, Form, Größe oder Höhe, sind sie optischen Daten überlegen und daher für viele Anwendungsbereiche im Kontext humanitärer Arbeit besonders. Die in den Fallstudien gewonnenen Erkenntnisse werden abschließend vor dem Hintergrund von Vor- und Nachteilen von Radardaten, sowie hinsichtlich zukünftiger Entwicklungen und Herausforderungen diskutiert. So versprechen neue Radarsatelliten und technologische Fortschritte im Bereich der Datenverarbeitung großes Potenzial. Gleichzeitig unterstreicht die Arbeit einen großen Bedarf an weiterer Forschung, sowie an Austausch und Zusammenarbeit zwischen Wissenschaftlern, Anwendern und Einsatzkräften vor Ort. Die vorliegende Arbeit ist die erste umfassende Darstellung und wissenschaftliche Aufarbeitung dieses Themenkomplexes. Sie soll als Grundstein für eine langfristige Integration von Radardaten in operationelle Abläufe dienen, um humanitäre Arbeit zu unterstützen und eine wirksame Hilfe für Menschen in Not ermöglichen

Mapping individual trees from airborne multi-sensor imagery

Airborne multi-sensor imaging is increasingly used to examine vegetation properties. The advantage of using multiple types of sensor is that each detects a different feature of the vegetation, so that collectively they provide a detailed understanding of the ecological pattern. Specifically, Light Detection And Ranging (LiDAR) devices produce detailed point clouds of where laser pulses have been backscattered from surfaces, giving information on vegetation structure; hyperspectral sensors measure reflectances within narrow wavebands, providing spectrally detailed information about the optical properties of targets; while aerial photographs provide high spatial-resolution imagery so that they can provide more feature details which cannot be identified from hyperspectral or LiDAR intensity images. Using a combination of these sensors, effective techniques can be developed for mapping species and inferring leaf physiological processes at ITC-level. Although multi-sensor approaches have revolutionised ecological research, their application in mapping individual tree crowns is limited by two major technical issues: (a) Multi-sensor imaging requires all images taken from different sensors to be co-aligned, but different sensor characteristics result in scale, rotation or translation mismatches between the images, making correction a pre-requisite of individual tree crown mapping; (b) reconstructing individual tree crowns from unstructured raw data space requires an accurate tree delineation algorithm. This thesis develops a schematic way to resolve these technical issues using the-state-of-the-art computer vision algorithms. A variational method, called NGF-Curv, was developed to co-align hyperspectral imagery, LiDAR and aerial photographs.NGF-Curv algorithm can deal with very complex topographic and lens distortions efficiently, thus improving the accuracy of co-alignment compared to established image registration methods for airborne data. A graph cut method, named MCNCP-RNC was developed to reconstruct individual tree crowns from fully integrated multi-sensor imagery. MCNCP-RNC is not influenced by interpolation artefacts because it detects trees in 3D, and it detects individual tree crowns using both hyperspectral imagery and LiDAR. Based on these algorithms, we developed a new workflow to detect species at pixel and ITC levels in a temperate deciduous forest in the UK. In addition, we modified the workflow to monitor physiological responses of two oak species with respect to environmental gradients in a Mediterranean woodland in Spain. The results show that our scheme can detect individual tree crowns, find species and monitor physiological responses of canopy leaves