Distributed learning: Developing a predictive model based on data from multiple hospitals without data leaving the hospital – A real life proof of concept

AbstractPurposeOne of the major hurdles in enabling personalized medicine is obtaining sufficient patient data to feed into predictive models. Combining data originating from multiple hospitals is difficult because of ethical, legal, political, and administrative barriers associated with data sharing. In order to avoid these issues, a distributed learning approach can be used. Distributed learning is defined as learning from data without the data leaving the hospital.Patients and methodsClinical data from 287 lung cancer patients, treated with curative intent with chemoradiation (CRT) or radiotherapy (RT) alone were collected from and stored in 5 different medical institutes (123 patients at MAASTRO (Netherlands, Dutch), 24 at Jessa (Belgium, Dutch), 34 at Liege (Belgium, Dutch and French), 48 at Aachen (Germany, German) and 58 at Eindhoven (Netherlands, Dutch)).A Bayesian network model is adapted for distributed learning (watch the animation: http://youtu.be/nQpqMIuHyOk). The model predicts dyspnea, which is a common side effect after radiotherapy treatment of lung cancer.ResultsWe show that it is possible to use the distributed learning approach to train a Bayesian network model on patient data originating from multiple hospitals without these data leaving the individual hospital. The AUC of the model is 0.61 (95%CI, 0.51–0.70) on a 5-fold cross-validation and ranges from 0.59 to 0.71 on external validation sets.ConclusionDistributed learning can allow the learning of predictive models on data originating from multiple hospitals while avoiding many of the data sharing barriers. Furthermore, the distributed learning approach can be used to extract and employ knowledge from routine patient data from multiple hospitals while being compliant to the various national and European privacy laws

Data Mining Applications in Banking Sector While Preserving Customer Privacy

In real-life data mining applications, organizations cooperate by using each other’s data on the same data mining task for more accurate results, although they may have different security and privacy concerns. Privacy-preserving data mining (PPDM) practices involve rules and techniques that allow parties to collaborate on data mining applications while keeping their data private. The objective of this paper is to present a number of PPDM protocols and show how PPDM can be used in data mining applications in the banking sector. For this purpose, the paper discusses homomorphic cryptosystems and secure multiparty computing. Supported by experimental analysis, the paper demonstrates that data mining tasks such as clustering and Bayesian networks (association rules) that are commonly used in the banking sector can be efficiently and securely performed. This is the first study that combines PPDM protocols with applications for banking data mining. Doi: 10.28991/ESJ-2022-06-06-014 Full Text: PD

Security in Data Mining- A Comprehensive Survey

Data mining techniques, while allowing the individuals to extract hidden knowledge on one hand, introduce a number of privacy threats on the other hand. In this paper, we study some of these issues along with a detailed discussion on the applications of various data mining techniques for providing security. An efficient classification technique when used properly, would allow an user to differentiate between a phishing website and a normal website, to classify the users as normal users and criminals based on their activities on Social networks (Crime Profiling) and to prevent users from executing malicious codes by labelling them as malicious. The most important applications of Data mining is the detection of intrusions, where different Data mining techniques can be applied to effectively detect an intrusion and report in real time so that necessary actions are taken to thwart the attempts of the intruder. Privacy Preservation, Outlier Detection, Anomaly Detection and PhishingWebsite Classification are discussed in this paper

Preservation of Patient Level Privacy: Federated Classification and Calibration Models

With the launching of the Precision Medicine Initiative in the United States, by the National Institute of Health, and the emergence of a large volume of electronic health records, there are many opportunities to improve clinical decision support systems. A large number of samples are needed to build predictive models that have adequate discrimination and calibration. However, protecting patient privacy is also an important issue. Patient data are typically protected in localized silos, and consolidation of datasets from different healthcare systems is difficult. Federated learning allows the training of a global model by amassing intermediate calculations from localized medical systems. The knowledge learned from the data can be transferred and aggregated to achieve better performance than the one achieved by individual local models. Federated learning may help build better models, providing more accurate predictions. There are two types of measures to assess how well a model performs: discrimination and calibration. While most papers report discrimination measures, calibration has often been neglected but it is a critical metric for evaluation. In this dissertation, I show a novel way to build classifiers and calibration models in a federated manner. I also show how I can evaluate and improve model calibration in this manner. Federated modeling enables the accumulation of knowledge and information that are otherwise locked behind local medical systems

Privacy Preservation and Analytical Utility of E-Learning Data Mashups in the Web of Data

Virtual learning environments contain valuable data about students that can be correlated and analyzed to optimize learning. Modern learning environments based on data mashups that collect and integrate data from multiple sources are relevant for learning analytics systems because they provide insights into students' learning. However, data sets involved in mashups may contain personal information of sensitive nature that raises legitimate privacy concerns. Average privacy preservation methods are based on preemptive approaches that limit the published data in a mashup based on access control and authentication schemes. Such limitations may reduce the analytical utility of the data exposed to gain students' learning insights. In order to reconcile utility and privacy preservation of published data, this research proposes a new data mashup protocol capable of merging and k-anonymizing data sets in cloud-based learning environments without jeopardizing the analytical utility of the information. The implementation of the protocol is based on linked data so that data sets involved in the mashups are semantically described, thereby enabling their combination with relevant educational data sources. The k-anonymized data sets returned by the protocol still retain essential information for supporting general data exploration and statistical analysis tasks. The analytical and empirical evaluation shows that the proposed protocol prevents individuals' sensitive information from re-identifying.The Spanish National Research Agency (AEI) funded this research through the project CREPES (ref. PID2020-115844RB-I00) with ERDF funds

PRIVACY PRESERVING DATA MINING TECHNIQUES USING RECENT ALGORITHMS

The privacy preserving data mining is playing crucial role act as rising technology to perform various data mining operations on private data and to pass on data in a secured way to protect sensitive data. Many types of technique such as randomization, secured sum algorithms and k-anonymity have been suggested in order to execute privacy preserving data mining. In this survey paper, on current researches made on privacy preserving data mining technique with fuzzy logic, neural network learning, secured sum and various encryption algorithm is presented. This will enable to grasp the various challenges faced in privacy preserving data mining and also help us to find best suitable technique for various data environment