A Robust and Artifact Resistant Algorithm of Ultrawideband Imaging System for Breast Cancer Detection.

Goal: Ultrawideband radar imaging is regarded as one of the most promising alternatives for breast cancer detection. A range of algorithms reported in literature show satisfactory tumor detection capabilities. However, most of algorithms suffer significant deterioration or even fail when the early-stage artifact, including incident signals and skin-fat interface reflections, cannot be perfectly removed from received signals. Furthermore, fibro-glandular tissue poses another challenge for tumor detection, due to the small dielectric contrast between glandular and cancerous tissues. Methods: This paper introduces a novel Robust and Artifact Resistant (RAR) algorithm, in which a neighborhood pairwise correlation-based weighting is designed to overcome the adverse effects from both artifact and glandular tissues. In RAR, backscattered signals are time-shifted, summed, and weighted by the maximum combination of the neighboring pairwise correlation coefficients between shifted signals, forming the intensity of each point within an imaging area. Results: The effectiveness was investigated using 3-D anatomically and dielectrically accurate finite-difference-time-domain numerical breast models. The use of neighborhood pairwise correlation provided robustness against artifact, and enabled the detection of multiple scatterers. RAR is compared with four well-known algorithms: delay-and-sum, delay-multiply-and-sum, modified-weighted-delay-and-sum, and filtered-delay-and-sum. Conclusion: It has shown that RAR exhibits improved identification capability, robust artifact resistance, and high detectability over its counterparts in most scenarios considered, while maintaining computational efficiency. Simulated tumors in both homogeneous and heterogonous, from mildly to moderately dense breast phantoms, combining an entropy-based artifact removal algorithm, were successfully identified and localized. Significance: These results show the strong potential of RAR for breast cancer screening

Reconstruction of Microwave Imaging using Machine Learning

Tese de mestrado, Engenharia Biomédica e Biofísica, 2022, Universidade de Lisboa, Faculdade de CiênciasBreast cancer is the most diagnosed cancer in women. The gold standard technique for mass screening is X-ray mammography, which requires the use of ionising radiation. Mammography has a high false positive rate for women under 50, since the technique is highly sensitive to breast density. Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET) and Ultrasound Imaging (US) have been suggested as complementary imaging tools to lessen the false positive results; however present some disadvantages. The potential of using microwave signals for breast cancer detection and monitoring has been studied for over 20 years. Microwave Breast Imaging (MBI) is a low-cost, non-invasive and non-ionising technique. The reflected microwave signals are transformed into an image via beamforming algorithms. These images have limited resolution, which may result in a considerable high rate of false positives and false negatives. In this dissertation, a complementary method of image reconstruction using Machine Learning (ML) models to predict the healthy or tumorous nature of breast is proposed. To study the potential of the proposed method, microwave signals were collected with a monostatic radar-based microwave system. The signal was acquired from three breast phantoms: one mimicking a homogeneous breast and two mimicking heterogeneous breasts. The phantoms had a cavity to introduce a plug, which included types of tumour models in terms of malignancies. From the signals, portions with and without tumour signature were extracted to train classification models. The most robust models were used to reconstruct a binary image of the breast with values of “hit” for tumorous focal points, and values of “miss” for healthy focal points. Eventually, the reconstructed images resulting from the proposed method were compared with the images obtained using the traditional beamforming method, DAS. Overall, the results obtained with the method ML-based were satisfactory, since for most phantoms the regions classified as tumour, indeed corresponded to the real position of the tumour

Recent Advances in Microwave Imaging for Breast Cancer Detection

Breast cancer is a disease that occurs most often in female cancer patients. Early detection can significantly reduce the mortality rate. Microwave breast imaging, which is noninvasive and harmless to human, offers a promising alternative method to mammography. This paper presents a review of recent advances in microwave imaging for breast cancer detection. We conclude by introducing new research on a microwave imaging system with time-domain measurement that achieves short measurement time and low system cost. In the time-domain measurement system, scan time would take less than 1 sec, and it does not require very expensive equipment such as VNA

UWB Pulse Radar for Human Imaging and Doppler Detection Applications

We were motivated to develop new technologies capable of identifying human life through walls. Our goal is to pinpoint multiple people at a time, which could pay dividends during military operations, disaster rescue efforts, or assisted-living. Such system requires the combination of two features in one platform: seeing-through wall localization and vital signs Doppler detection. Ultra-wideband (UWB) radar technology has been used due to its distinct advantages, such as ultra-low power, fine imaging resolution, good penetrating through wall characteristics, and high performance in noisy environment. Not only being widely used in imaging systems and ground penetrating detection, UWB radar also targets Doppler sensing, precise positioning and tracking, communications and measurement, and etc. A robust UWB pulse radar prototype has been developed and is presented here. The UWB pulse radar prototype integrates seeing-through imaging and Doppler detection features in one platform. Many challenges existing in implementing such a radar have been addressed extensively in this dissertation. Two Vivaldi antenna arrays have been designed and fabricated to cover 1.5-4.5 GHz and 1.5-10 GHz, respectively. A carrier-based pulse radar transceiver has been implemented to achieve a high dynamic range of 65dB. A 100 GSPS data acquisition module is prototyped using the off-the-shelf field-programmable gate array (FPGA) and analog-to-digital converter (ADC) based on a low cost solution: equivalent time sampling scheme. Ptolemy and transient simulation tools are used to accurately emulate the linear and nonlinear components in the comprehensive simulation platform, incorporated with electromagnetic theory to account for through wall effect and radar scattering. Imaging and Doppler detection examples have been given to demonstrate that such a “Biometrics-at-a-glance” would have a great impact on the security, rescuing, and biomedical applications in the future