A new pulse coupled neural network (PCNN) for brain medical image fusion empowered by shuffled frog leaping algorithm

Recent research has reported the application of image fusion technologies in medical images in a wide range of aspects, such as in the diagnosis of brain diseases, the detection of glioma and the diagnosis of Alzheimer’s disease. In our study, a new fusion method based on the combination of the shuffled frog leaping algorithm (SFLA) and the pulse coupled neural network (PCNN) is proposed for the fusion of SPECT and CT images to improve the quality of fused brain images. First, the intensity-hue-saturation (IHS) of a SPECT and CT image are decomposed using a non-subsampled contourlet transform (NSCT) independently, where both low-frequency and high-frequency images, using NSCT, are obtained. We then used the combined SFLA and PCNN to fuse the high-frequency sub-band images and low-frequency images. The SFLA is considered to optimize the PCNN network parameters. Finally, the fused image was produced from the reversed NSCT and reversed IHS transforms. We evaluated our algorithms against standard deviation (SD), mean gradient (Ḡ), spatial frequency (SF) and information entropy (E) using three different sets of brain images. The experimental results demonstrated the superior performance of the proposed fusion method to enhance both precision and spatial resolution significantly

Solving Inverse Problems with Piecewise Linear Estimators: From Gaussian Mixture Models to Structured Sparsity

A general framework for solving image inverse problems is introduced in this paper. The approach is based on Gaussian mixture models, estimated via a computationally efficient MAP-EM algorithm. A dual mathematical interpretation of the proposed framework with structured sparse estimation is described, which shows that the resulting piecewise linear estimate stabilizes the estimation when compared to traditional sparse inverse problem techniques. This interpretation also suggests an effective dictionary motivated initialization for the MAP-EM algorithm. We demonstrate that in a number of image inverse problems, including inpainting, zooming, and deblurring, the same algorithm produces either equal, often significantly better, or very small margin worse results than the best published ones, at a lower computational cost.Comment: 30 page

Enhancing Image Quality: A Comparative Study of Spatial, Frequency Domain, and Deep Learning Methods

Image restoration and noise reduction methods have been created to restore deteriorated images and improve their quality. These methods have garnered substantial significance in recent times, mainly due to the growing utilization of digital imaging across diverse domains, including but not limited to medical imaging, surveillance, satellite imaging, and numerous others. In this paper, we conduct a comparative analysis of three distinct approaches to image restoration: the spatial method, the frequency domain method, and the deep learning method. The study was conducted on a dataset of 10,000 images, and the performance of each method was evaluated using the accuracy and loss metrics. The results show that the deep learning method outperformed the other two methods, achieving a validation accuracy of 72.68% after 10 epochs. The spatial method had the lowest accuracy of the three, achieving a validation accuracy of 69.98% after 10 epochs. The FFT frequency domain method had a validation accuracy of 52.87% after 10 epochs, significantly lower than the other two methods. The study demonstrates that deep learning is a promising approach for image classification tasks and outperforms traditional methods such as spatial and frequency domain techniques

An improved approach for medical image fusion using sparse representation and Siamese convolutional neural network

Multimodal image fusion is a contemporary branch of medical imaging that aims to increase the accuracy of clinical diagnosis of the disease stage development. The fusion of different image modalities can be a viable medical imaging approach. It combines the best features to produce a composite image with higher quality than its predecessors and can significantly improve medical diagnosis. Recently, sparse representation (SR) and Siamese Convolutional Neural Network (SCNN) methods have been introduced independently for image fusion. However, some of the results from these approaches have recorded defects, such as edge blur, less visibility, and blocking artifacts. To remedy these deficiencies, in this paper, a smart blending approach based on a combination of SR and SCNN is introduced for image fusion, which comprises three steps as follows. Firstly, entire source images are fed into the classical orthogonal matching pursuit (OMP), where the SR-fused image is obtained using the max-rule that aims to improve pixel localization. Secondly, a novel scheme of SCNN-based K-SVD dictionary learning is re-employed for each source image. The method has shown good non-linearity behavior, contributing to increasing the fused output's sparsity characteristics and demonstrating better extraction and transfer of image details to the output fused image. Lastly, the fusion rule step employs a linear combination between steps 1 and 2 to obtain the final fused image. The results depict that the proposed method is advantageous, compared to other previous methods, notably by suppressing the artifacts produced by the traditional SR and SCNN model

Deep learning assisted MRI guided attenuation correction in PET

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University LondonPositron emission tomography (PET) is a unique imaging modality that provides physiological and functional details of the tissue at the molecular level. However, the acquired PET images have some limitations such as the attenuation. PET attenuation correction is an essential step to obtain the full potential of PET quantification. With the wide use of hybrid PET/MR scanners, magnetic resonance (MR) images are used to address the problem of PET attenuation correction. The MR images segmentation is one simple and robust approach to create pseudo computed tomography (CT) images, which are used to generate attenuation coefficient maps to correct the PET attenuation. Recently, deep learning has been proposed and used as a promising technique to efficiently perform MR and various medical images segmentation. In this research work, deep learning guided segmentation approaches have been proposed to enhance the bone class segmentation of MR brain images in order to generate accurate pseudo-CT images. The first approach has introduced the combination of handcrafted features with deep learning features to enrich the set of features. Multiresolution analysis techniques, which generate multiscale and multidirectional coefficients of an image such as contourlet and shearlet transforms, are applied and combined with deep convolutional neural network (CNN) features. Different experiments have been conducted to investigate the number of selected coefficients and the insertion location of the handcrafted features. The second approach aims at reducing the segmentation algorithm’s complexity while maintaining the segmentation performance. An attention based convolutional encode-decoder network has been proposed to adaptively recalibrate the deep network features. This attention based network consists of two different squeeze and excitation blocks that excite the features spatially and channel wise. The two blocks are combined sequentially to decrease the number of network’s parameters and reduces the model complexity. The third approach has been focuses on the application of transfer learning from different MR sequences such as T1 weighted (T1-w) and T2 weighted (T2-w) images. A pretrained model with T1-w MR sequences is fine tuned to perform the segmentation of T2-w images. Multiple fine tuning approaches and experiments have been conducted to study the best fine tuning mechanism that is able to build an efficient segmentation model for both T1-w and T2-w segmentation. Clinical datasets of fifty patients with different conditions and diagnosis have been used to carry an objective evaluation to measure the segmentation performance of the results obtained by the three proposed methods. The first and second approaches have been validated with other studies in the literature that applied deep network based segmentation technique to perform MR based attenuation correction for PET images. The proposed methods have shown an enhancement in the bone segmentation with an increase of dice similarity coefficient (DSC) from 0.6179 to 0.6567 using an ensemble of CNNs with an improvement percentage of 6.3%. The proposed excitation-based CNN has decreased the model complexity by decreasing the number of trainable parameters by more than 46% where less computing resources are required to train the model. The proposed hybrid transfer learning method has shown its superiority to build a multi-sequences (T1-w and T2-w) segmentation approach compared to other applied transfer learning methods especially with the bone class where the DSC is increased from 0.3841 to 0.5393. Moreover, the hybrid transfer learning approach requires less computing time than transfer learning using open and conservative fine tuning

A Novel Multi-Focus Image Fusion Method Based on Stochastic Coordinate Coding and Local Density Peaks Clustering

abstract: The multi-focus image fusion method is used in image processing to generate all-focus images that have large depth of field (DOF) based on original multi-focus images. Different approaches have been used in the spatial and transform domain to fuse multi-focus images. As one of the most popular image processing methods, dictionary-learning-based spare representation achieves great performance in multi-focus image fusion. Most of the existing dictionary-learning-based multi-focus image fusion methods directly use the whole source images for dictionary learning. However, it incurs a high error rate and high computation cost in dictionary learning process by using the whole source images. This paper proposes a novel stochastic coordinate coding-based image fusion framework integrated with local density peaks. The proposed multi-focus image fusion method consists of three steps. First, source images are split into small image patches, then the split image patches are classified into a few groups by local density peaks clustering. Next, the grouped image patches are used for sub-dictionary learning by stochastic coordinate coding. The trained sub-dictionaries are combined into a dictionary for sparse representation. Finally, the simultaneous orthogonal matching pursuit (SOMP) algorithm is used to carry out sparse representation. After the three steps, the obtained sparse coefficients are fused following the max L1-norm rule. The fused coefficients are inversely transformed to an image by using the learned dictionary. The results and analyses of comparison experiments demonstrate that fused images of the proposed method have higher qualities than existing state-of-the-art methods

CoCoNet: Coupled Contrastive Learning Network with Multi-level Feature Ensemble for Multi-modality Image Fusion

Infrared and visible image fusion targets to provide an informative image by combining complementary information from different sensors. Existing learning-based fusion approaches attempt to construct various loss functions to preserve complementary features from both modalities, while neglecting to discover the inter-relationship between the two modalities, leading to redundant or even invalid information on the fusion results. To alleviate these issues, we propose a coupled contrastive learning network, dubbed CoCoNet, to realize infrared and visible image fusion in an end-to-end manner. Concretely, to simultaneously retain typical features from both modalities and remove unwanted information emerging on the fused result, we develop a coupled contrastive constraint in our loss function.In a fused imge, its foreground target/background detail part is pulled close to the infrared/visible source and pushed far away from the visible/infrared source in the representation space. We further exploit image characteristics to provide data-sensitive weights, which allows our loss function to build a more reliable relationship with source images. Furthermore, to learn rich hierarchical feature representation and comprehensively transfer features in the fusion process, a multi-level attention module is established. In addition, we also apply the proposed CoCoNet on medical image fusion of different types, e.g., magnetic resonance image and positron emission tomography image, magnetic resonance image and single photon emission computed tomography image. Extensive experiments demonstrate that our method achieves the state-of-the-art (SOTA) performance under both subjective and objective evaluation, especially in preserving prominent targets and recovering vital textural details.Comment: 25 pages, 16 figure