Rotationally Invariant Image Representation for Viewing Direction Classification in Cryo-EM

We introduce a new rotationally invariant viewing angle classification method for identifying, among a large number of Cryo-EM projection images, similar views without prior knowledge of the molecule. Our rotationally invariant features are based on the bispectrum. Each image is denoised and compressed using steerable principal component analysis (PCA) such that rotating an image is equivalent to phase shifting the expansion coefficients. Thus we are able to extend the theory of bispectrum of 1D periodic signals to 2D images. The randomized PCA algorithm is then used to efficiently reduce the dimensionality of the bispectrum coefficients, enabling fast computation of the similarity between any pair of images. The nearest neighbors provide an initial classification of similar viewing angles. In this way, rotational alignment is only performed for images with their nearest neighbors. The initial nearest neighbor classification and alignment are further improved by a new classification method called vector diffusion maps. Our pipeline for viewing angle classification and alignment is experimentally shown to be faster and more accurate than reference-free alignment with rotationally invariant K-means clustering, MSA/MRA 2D classification, and their modern approximations

Rotation-invariant features for multi-oriented text detection in natural images.

Texts in natural scenes carry rich semantic information, which can be used to assist a wide range of applications, such as object recognition, image/video retrieval, mapping/navigation, and human computer interaction. However, most existing systems are designed to detect and recognize horizontal (or near-horizontal) texts. Due to the increasing popularity of mobile-computing devices and applications, detecting texts of varying orientations from natural images under less controlled conditions has become an important but challenging task. In this paper, we propose a new algorithm to detect texts of varying orientations. Our algorithm is based on a two-level classification scheme and two sets of features specially designed for capturing the intrinsic characteristics of texts. To better evaluate the proposed method and compare it with the competing algorithms, we generate a comprehensive dataset with various types of texts in diverse real-world scenes. We also propose a new evaluation protocol, which is more suitable for benchmarking algorithms for detecting texts in varying orientations. Experiments on benchmark datasets demonstrate that our system compares favorably with the state-of-the-art algorithms when handling horizontal texts and achieves significantly enhanced performance on variant texts in complex natural scenes

High-resolution ab initio three-dimensional X-ray diffraction microscopy

Coherent X-ray diffraction microscopy is a method of imaging non-periodic isolated objects at resolutions only limited, in principle, by the largest scattering angles recorded. We demonstrate X-ray diffraction imaging with high resolution in all three dimensions, as determined by a quantitative analysis of the reconstructed volume images. These images are retrieved from the 3D diffraction data using no a priori knowledge about the shape or composition of the object, which has never before been demonstrated on a non-periodic object. We also construct 2D images of thick objects with infinite depth of focus (without loss of transverse spatial resolution). These methods can be used to image biological and materials science samples at high resolution using X-ray undulator radiation, and establishes the techniques to be used in atomic-resolution ultrafast imaging at X-ray free-electron laser sources.Comment: 22 pages, 11 figures, submitte

Towards Analyzing Semantic Robustness of Deep Neural Networks

Despite the impressive performance of Deep Neural Networks (DNNs) on various vision tasks, they still exhibit erroneous high sensitivity toward semantic primitives (e.g. object pose). We propose a theoretically grounded analysis for DNN robustness in the semantic space. We qualitatively analyze different DNNs' semantic robustness by visualizing the DNN global behavior as semantic maps and observe interesting behavior of some DNNs. Since generating these semantic maps does not scale well with the dimensionality of the semantic space, we develop a bottom-up approach to detect robust regions of DNNs. To achieve this, we formalize the problem of finding robust semantic regions of the network as optimizing integral bounds and we develop expressions for update directions of the region bounds. We use our developed formulations to quantitatively evaluate the semantic robustness of different popular network architectures. We show through extensive experimentation that several networks, while trained on the same dataset and enjoying comparable accuracy, do not necessarily perform similarly in semantic robustness. For example, InceptionV3 is more accurate despite being less semantically robust than ResNet50. We hope that this tool will serve as a milestone towards understanding the semantic robustness of DNNs.Comment: Presented at European conference on computer vision (ECCV 2020) Workshop on Adversarial Robustness in the Real World ( https://eccv20-adv-workshop.github.io/ ) [best paper award]. The code is available at https://github.com/ajhamdi/semantic-robustnes