Bayesian Spatial Binary Regression for Label Fusion in Structural Neuroimaging

Many analyses of neuroimaging data involve studying one or more regions of interest (ROIs) in a brain image. In order to do so, each ROI must first be identified. Since every brain is unique, the location, size, and shape of each ROI varies across subjects. Thus, each ROI in a brain image must either be manually identified or (semi-) automatically delineated, a task referred to as segmentation. Automatic segmentation often involves mapping a previously manually segmented image to a new brain image and propagating the labels to obtain an estimate of where each ROI is located in the new image. A more recent approach to this problem is to propagate labels from multiple manually segmented atlases and combine the results using a process known as label fusion. To date, most label fusion algorithms either employ voting procedures or impose prior structure and subsequently find the maximum a posteriori estimator (i.e., the posterior mode) through optimization. We propose using a fully Bayesian spatial regression model for label fusion that facilitates direct incorporation of covariate information while making accessible the entire posterior distribution. We discuss the implementation of our model via Markov chain Monte Carlo and illustrate the procedure through both simulation and application to segmentation of the hippocampus, an anatomical structure known to be associated with Alzheimer's disease.Comment: 24 pages, 10 figure

Quality assessment by region in spot images fused by means dual-tree complex wavelet transform

This work is motivated in providing and evaluating a fusion algorithm of remotely sensed images, i.e. the fusion of a high spatial resolution panchromatic image with a multi-spectral image (also known as pansharpening) using the dual-tree complex wavelet transform (DT-CWT), an effective approach for conducting an analytic and oversampled wavelet transform to reduce aliasing, and in turn reduce shift dependence of the wavelet transform. The proposed scheme includes the definition of a model to establish how information will be extracted from the PAN band and how that information will be injected into the MS bands with low spatial resolution. The approach was applied to Spot 5 images where there are bands falling outside PAN’s spectrum. We propose an optional step in the quality evaluation protocol, which is to study the quality of the merger by regions, where each region represents a specific feature of the image. The results show that DT-CWT based approach offers good spatial quality while retaining the spectral information of original images, case SPOT 5. The additional step facilitates the identification of the most affected regions by the fusion process