18,752 research outputs found
Identity, Power, and Prestige in Switzerland's Multilingual Education
Switzerland is known for its multilingualism, yet not all languages are represented equally in society. The situation is exacerbated by the influx of heritage languages and English through migration and globalization processes which challenge the traditional education system. This study is the first to investigate how schools in Grisons, Fribourg, and Zurich negotiate neoliberal forces leading to a growing necessity of English, a romanticized view on national languages, and the social justice perspective of institutionalizing heritage languages. It uncovers power and legitimacy issues and showcases students' and teachers' complex identities to advocate equitable multilingual education
Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application
Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fi t in perfectly as a novel market group known as nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies are increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, β-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity
Grasping nothing: a study of minimal ontologies and the sense of music
If music were to have a proper sense – one in which it is truly given – one might reasonably place this in sound and aurality. I contend, however, that no such sense exists; rather, the sense of music takes place, and it does so with the impossible. To this end, this thesis – which is a work of philosophy and music – advances an ontology of the impossible (i.e., it thinks the being of what, properly speaking, can have no being) and considers its implications for music, articulating how ontological aporias – of the event, of thinking the absolute, and of sovereignty’s dismemberment – imply senses of music that are anterior to sound. John Cage’s Silent Prayer, a nonwork he never composed, compels a rerethinking of silence on the basis of its contradictory status of existence; Florian Hecker et al.’s Speculative Solution offers a basis for thinking absolute music anew to the precise extent that it is a discourse of meaninglessness; and Manfred Werder’s [yearn] pieces exhibit exemplarily that music’s sense depends on the possibility of its counterfeiting. Inso-much as these accounts produce musical senses that take the place of sound, they are also understood to be performances of these pieces. Here, then, thought is music’s organon and its instrument
High-performance and Scalable Software-based NVMe Virtualization Mechanism with I/O Queues Passthrough
NVMe(Non-Volatile Memory Express) is an industry standard for solid-state
drives (SSDs) that has been widely adopted in data centers. NVMe virtualization
is crucial in cloud computing as it allows for virtualized NVMe devices to be
used by virtual machines (VMs), thereby improving the utilization of storage
resources. However, traditional software-based solutions have flexibility
benefits but often come at the cost of performance degradation or high CPU
overhead. On the other hand, hardware-assisted solutions offer high performance
and low CPU usage, but their adoption is often limited by the need for special
hardware support or the requirement for new hardware development.
In this paper, we propose LightIOV, a novel software-based NVMe
virtualization mechanism that achieves high performance and scalability without
consuming valuable CPU resources and without requiring special hardware
support. LightIOV can support thousands of VMs on each server. The key idea
behind LightIOV is NVMe hardware I/O queues passthrough, which enables VMs to
directly access I/O queues of NVMe devices, thus eliminating virtualization
overhead and providing near-native performance. Results from our experiments
show that LightIOV can provide comparable performance to VFIO, with an IOPS of
97.6%-100.2% of VFIO. Furthermore, in high-density VMs environments, LightIOV
achieves 31.4% lower latency than SPDK-Vhost when running 200 VMs, and an
improvement of 27.1% in OPS performance in real-world applications
Convergence Rate of Nonconvex Douglas-Rachford splitting via merit functions, with applications to weakly convex constrained optimization
We analyze Douglas-Rachford splitting techniques applied to solving weakly
convex optimization problems. Under mild regularity assumptions, and by the
token of a suitable merit function, we show convergence to critical points and
local linear rates of convergence. The merit function, comparable to the Moreau
envelope in Variational Analysis, generates a descent sequence, a feature that
allows us to extend to the non-convex setting arguments employed in convex
optimization. A by-product of our approach is a ADMM-like method for
constrained problems with weakly convex objective functions. When specialized
to multistage stochastic programming, the proposal yields a nonconvex version
of the Progressive Hedging algorithm that converges with linear speed. The
numerical assessment on a battery of phase retrieval problems shows promising
numerical performance of our method, when compared to existing algorithms in
the literature.Comment: 24 pages, 1 figur
Gender diversity and earnings management: the case of female directors with financial background
Past evidence generally suggests that the presence of female directors on corporate boards tends to improve earnings quality due to these directors’ superior monitoring abilities. However, it is not clear which characteristics and skills of female directors drive such abilities. In this paper, we focus on the financial background of female directors, an area which remains largely unexplored in existing literature. The results show that the participation of female directors with relevant financial background improves earnings quality more than the participation of female directors without such background. In addition, our findings suggest that only female directors possessing relevant financial background and having fewer outside directorships are able to mitigate earnings management and therefore overcommitting expert female directors with more outside directorships would diminish their monitoring ability. We did not find any evidence suggesting that female directors without relevant financial background are able to mitigate earnings management, irrespective of their outside directorships or tenure. We interpret our findings within a theoretical framework that draws on a number of economic and social theories. The results are generally robust after controlling for potential endogeneity problems
Reproduction, body condition, age, and growth of a large sandy intertidal bivalve, Tivela stultorum
The iconic Pismo clam Tivela stultorum (Mawe, 1823) once supported a thriving commercial and recreational fishery in California, but populations have declined statewide in recent decades, in part due to overfishing. To manage and restore populations, fishery managers need accurate life history information, but critical data on reproductive cycles, maturity, and growth rates is either unknown or many decades old. This project aimed to (1) determine annual reproductive cycles and body condition of Pismo clams; (2) identify environmental drivers of reproduction and body condition; (3) determine size-age relationships among clams in California; and (4) estimate growth rates. Up to 70 clams mo-1 were collected from Pismo Beach, CA, for histological analysis to determine reproductive stage, measure a body condition index, and estimate ages from shells. Additional clams and shells were collected from sites north and south of Point Conception to compare growth and age at legal size between these 2 major oceanographic zones. Data suggests that reproductive timing deviates only slightly from historical records, with clams spawning later in the year than decades ago. Body condition indices correlate with reproductive stage 3 Ripe, providing an inexpensive proxy to monitor Pismo clam reproduction. Growth was faster in warmer Southern California compared to Central California, but still substantially slower than historical estimates; we estimate that Pismo clams reach the current legal size (114 mm) in 11.1 yr, several years later than previous estimates. Collectively, these data are critical to improve and guide management decisions for this once-abundant species
Centro especializado de Salud Mental Comunitario en Cajamarca
El presente proyecto de tesis realiza un análisis de la problemática actual en los
servicios de salud mental en la ciudad de Cajamarca.
En la actualidad existe solo un Centro de Salud Mental Comunitario, denominado
“Esperanza de Vida”, este fue creado de forma temporal e improvisada, sin contar
con el equipamiento e infraestructura que brindar la atención adecuada de los
usuarios.
El trabajo de investigación contiene la fundamentación del proyecto donde se
describe las normas, antecedentes históricos y referentes siguiendo el enfoque
comunitario, además el desarrollo de la propuesta arquitectónica y sus
especialidades.
El proyecto arquitectónico está diseñado para satisfacer las necesidades de los
pacientes y la comunidad. Brindará servicios de tratamiento y diagnóstico de
pacientes, así como su rehabilitación mediante terapias individuales y grupales,
además de la intervención comunitaria a través de talleres.This thesis project carries out an analysis of the current problems in mental health
services in the city of Cajamarca.
Currently there is only one Community Mental Health Center, called “Esperanza de
Vida”, this was created temporarily and improvised, without having the equipment
and infrastructure that will provide adequate care for users.
The research work contains the foundation of the project where the norms, historical
antecedents and references are described following the community approach, in
addition to the development of the architectural proposal and its specialties.
The architectural project is designed to meet the needs of patients and the
community. It will provide treatment and diagnosis services for patients, as well as
their rehabilitation through individual and group therapies, in addition to community
intervention through workshopsTesi
Samoupravljanje u kulturi: opera Narodnog Pozorišta u Beogradu (1970–1990)
Temeljna polazišta ovog rada oslanjaju se na istraživanja, analizu i interpretaciju samoupravljanja u kulturi u kontekstu rada i delovanja Opere Narodnog pozorišta u Beogradu od 1970. do 1990. godine. Osnovna hipoteza, koja nameće više pojedinačnih pretpostavki, jeste neadekvatnost ideje samoupravnog sistema i njenog željenog cilja. U ovom smislu, sagledava se pitanje uvođenja samoupravljanja na svim nivoima jugoslovenskog socijalističkog društva, a posebno u oblasti kulture. U strukturi sadržaja ovog rada, ova hipoteza analizira se i sagledava kroz poglavlja koja se odnose na predstavljanje idejnih okvira samoupravljanja u kulturi; na zapažene paradokse između željenog modela socijalističkog samoupravnog sistema u polju kulture i prakse, koja je posebno analizirana na studiji slučaja, odnosno, implementiranja ovakvog sistema u rad Opere Narodnog pozorišta u Beogradu u periodu od 1970. do 1990. godine.
Međusobna neadekvatnost ideje i prakse ispituje se, tumači i interpretira uvođenjem pojmova subjekta i prostora i njihovih relacija, što predstavlja teorijsko metodološki okvir rada. Za potrebe tumačenja ovih odnosa, socijalistički čovek razmatra se kao adekvatan subjekt, a elitna kultura/„kultura ugledanja“ kao adekvatan prostor za kreiranje svestrane, aktivne i stvaralačke ličnosti. Diskrepanca između ovih pojmova i njihovih odnosa primećuje se na primeru rada beogradske Opere. U studiji slučaja detektuju se referentni parametri koji izmiču postavci idealnog modela, a to su: Opera kao institucija, opera kao žanr, kao i tri vrste subjekata koji su u relaciji sa Operom/operom (subjekt-radnik u privredi, subjekt-radnik u kulturi, subjekt-umetnik). U tom smislu, cilj rada u celini jeste da ukaže na hibridan model samoupravljanja u kulturi i konkretno, na moguće posledice uvođenja takvog modela u instituciju kulture kao što je Opera. Sledstveno tome, te posledice se mogu identifikovati u njenoj organizacionoj strukturi, u sagledavanju statusa umetnika i u oblikovanju repertoarske politike
Gene Editing Improves the Agronomic Important Traits of Wheat. CRISPR-Cas9 and Cas12/Cpf1
A hexaploid Wheat (Triticum aestivum L.) is the 3rd most important staple food crop with 15% caloric intake next to maize and rice in the world. The global attention for wheat improvement are still encouraging. However, the population growth and demand for food at this time and in the next years could not be balanced. Due to this, huge investments have been established and performed to improve the most important agronomic traits of wheat. Among the new molecular tools and techniques that have given a big emphasis as it will have many concerns is gene editing. Many gene editing tools have been reported and being implemented including Zinc finger nuclease, transcription activator-like effector nuclease, and clustered regularly interspaced short palindromic repeats associated Cas9/12 system for targeted gene editing. Among these, clustered regularly interspaced short palindromic repeats associated Cas9/12 systems are very accurate and widely used for targeted gene editing. By using CRISPR-Cas mediated gene editing technique, important traits of wheat include disease and pest resistance, better grain and flour quality, gluten-free trait, better nutritional value, nitrogen use efficiency, threshability, and other yield components and has been edited and improved. Therefore, the use of gene editing technologies for wheat as well as other important crops improvement was irreversible
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