15,263 research outputs found

    Integração de uma norma de segurança alimentar (IFS) no SGQ da Adega de Ponte de Lima

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    Mestrado em Gestão da Qualidade e Segurança Alimentar na Escola Superior de Tecnologia e Gestão do Instituto Politécnico de Viana do CasteloHoje em dia as organizações da área alimentar estão sujeitas a um grau constante de incertezas, mudanças, e a um grande número de leis e regulamentos rigorosos criados para assegurar a qualidade e segurança dos produtos alimentares. A indústria alimentar tem vindo a adaptar-se, constantemente de forma a ultrapassar todos estes desafios para obter produtos seguros e com um elevado nível de confiança para o consumidor. A implementação e certificação de normas relativas ao cumprimento de requisitos da qualidade e da segurança alimentar é fundamental para garantir e promover a competitividade e o reconhecimento destas organizações ao nível nacional e internacional. A Adega de Ponte de Lima (APL) tem atualmente implementada a NP EN ISO 9001:2015. O presente trabalho tem como objetivos principais fazer a transição da atual norma para a versão de 2015 (NP EN ISO 9001:2015) e também estudar a possível integração da norma de gestão e segurança alimentar IFS Food (International Featured Standarts) – Versão 6 na APL. Para tal, foi realizada uma análise comparativa entre os dois referenciais normativos e proposto um plano de ações requisito a requisito. Relativamente ao trabalho sobre a integração da norma IFS Food foi revisto e proposto um novo plano HACCP para a futura implementação deste sistema de gestão e segurança alimentar. Quanto ao plano HACCP proposto conclui-se que é possível a sua aplicação no local, embora este ainda não se encontre implementado. Do trabalho realizado conclui-se que o sistema de gestão e segurança alimentar, segundo IFS Food pode ser integrado no sistema de gestão da qualidade (SGQ) gerando um sistema de gestão integrado (SGI). Este compreende um conjunto de procedimentos organizacionais capazes de garantir que as atividades importantes da qualidade e da segurança alimentar decorram de forma controlada e eficaz.Food organizations today are subject to uncertainties and changes, on a daily basis, and also subject to a big number of laws and strict standards in order to secure the quality and safety of the food products. Mainly, this organizations are adapting, reinventing and innovating in the way of overcome this challenges. The implementation and regulation of quality and security in the food products is crucial to insure the competitive and knowledge of this organizations, nationally and internationally. The Ponte de Lima Winery (APL) has currently implemented NP EN ISO 9001: 2018. Thus, the main objective of this work is to insure the transition from the current standard, to the 2015 version (NP EN ISO 9001: 2015) and to study the possible integration of the IFS Food (International Featured Standarts) into APL. To do this, a comparative analysis was created between the two normative references and a proposed action plan was design. Regarding the work on the integration of the IFS Food standard, a new HACCP plan for the future implementation of this food safety management system was revised and proposed. As regards the proposed HACCP plan, it is concluded that it is possible to apply it on the APL, although it has not yet been implemented. Thus, it can be concluded that the food safety management system according to IFS Food can be integrated into the quality management system (QMS), generating an integrated quality management and food safety system (IMS). It comprises a set of organizational procedures capable of ensuring that important quality and food safety activities take place in a controlled and effective manner

    Теорія систем мобільних інфокомунікацій. Системна архітектура

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    Навчальний посібник містить опис логічних та фізичних структур, процедур, алгоритмів, протоколів, принципів побудови і функціонування мереж стільникового мобільного зв’язку (до 3G) і мобільних інфокомунікацій (4G і вище), приділяючи увагу розгляду загальних архітектур мереж операторів мобільного зв’язку, їх управління і координування, неперервності еволюції розвитку засобів функціонування і способів надання послуг таких мереж. Посібник структурно має сім розділів і побудований так, що складність матеріалу зростає з кожним наступним розділом. Навчальний посібник призначено для здобувачів ступеня бакалавра за спеціальністю 172 «Телекомунікації та радіотехніка», буде також корисним для аспірантів, наукових та інженерно-технічних працівників за напрямом інформаційно-телекомунікаційних систем та технологій.The manual contains a description of the logical and physical structures, procedures, algorithms, protocols, principles of construction and operation of cellular networks for mobile communications (up to 3G) and mobile infocommunications (4G and higher), paying attention to the consideration of general architectures of mobile operators' networks, their management, and coordination, the continuous evolution of the development of the means of operation and methods of providing services of such networks. The manual has seven structural sections and is structured in such a way that the complexity of the material increases with each subsequent chapter. The textbook is intended for applicants for a bachelor's degree in specialty 172 "Telecommunications and Radio Engineering", and will also be useful to graduate students, and scientific and engineering workers in the direction of information and telecommunication systems and technologies

    Norsk rå kumelk, en kilde til zoonotiske patogener?

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    The worldwide emerging trend of eating “natural” foods, that has not been processed, also applies for beverages. According to Norwegian legislation, all milk must be pasteurized before commercial sale but drinking milk that has not been heat-treated, is gaining increasing popularity. Scientist are warning against this trend and highlights the risk of contracting disease from milkborne microorganisms. To examine potential risks associated with drinking unpasteurized milk in Norway, milk- and environmental samples were collected from dairy farms located in south-east of Norway. The samples were analyzed for the presence of specific zoonotic pathogens; Listeria monocytogenes, Campylobacter spp., and Shiga toxin-producing Escherichia coli (STEC). Cattle are known to be healthy carriers of these pathogens, and Campylobacter spp. and STEC have a low infectious dose, meaning that infection can be established by ingesting a low number of bacterial cells. L. monocytogenes causes one of the most severe foodborne zoonotic diseases, listeriosis, that has a high fatality rate. All three pathogens have caused milk borne disease outbreaks all over the world, also in Norway. During this work, we observed that the prevalence of the three examined bacteria were high in the environment at the examined farms. In addition, 7% of the milk filters were contaminated by STEC, 13% by L. monocytogenes and 4% by Campylobacter spp. Four of the STEC isolates detected were eaepositive, which is associated with the capability to cause severe human disease. One of the eae-positive STEC isolates were collected from a milk filter, which strongly indicate that Norwegian raw milk may contain potential pathogenic STEC. To further assess the possibilities of getting ill by STEC after consuming raw milk, we examined the growth of the four eae-positive STEC isolates in raw milk at different temperatures. All four isolates seemed to have ability to multiply in raw milk at 8°C, and one isolate had significant growth after 72 hours. Incubation at 6°C seemed to reduce the number of bacteria during the first 24 hours before cell death stopped. These findings highlight the importance of stable refrigerator temperatures, preferable < 4°C, for storage of raw milk. The L. monocytogenes isolates collected during this study show genetic similarities to isolates collected from urban and rural environmental locations, but different clones were predominant in agricultural environments compared to clinical and food environments. However, the results indicate that the same clone can persist in a farm over time, and that milk can be contaminated by L. monocytogenes clones present in farm environment. Despite testing small volumes (25 mL) of milk, we were able to isolate both STEC and Campylobacter spp. directly from raw milk. A proportion of 3% of the bulk tank milk and teat milk samples were contaminated by Campylobacter spp. and one STEC was isolated from bulk tank milk. L monocytogenes was not detected in bulk tank milk, nor in teat milk samples. The agricultural evolvement during the past decades have led to larger production units and new food safety challenges. Dairy cattle production in Norway is in a current transition from tie-stall housing with conventional pipeline milking systems, to modern loose housing systems with robotic milking. The occurrence of the three pathogens in this project were higher in samples collected from farms with loose housing compared to those with tiestall housing. Pasteurization of cow’s milk is a risk reducing procedure to protect consumers from microbial pathogens and in most EU countries, commercial distribution of unpasteurized milk is legally restricted. Together, the results presented in this thesis show that the animal housing may influence the level of pathogenic bacteria in the raw milk and that ingestion of Norwegian raw cow’s milk may expose consumers to pathogenic bacteria which can cause severe disease, especially in children, elderly and in persons with underlying diseases. The results also highlight the importance of storing raw milk at low temperatures between milking and consumption.Å spise mat som er mindre prosessert og mer «naturlig» er en pågående trend i Norge og i andre deler av verden. Interessen for å drikke melk som ikke er varmebehandlet, såkalt rå melk, er også økende. I Norge er det påbudt å pasteurisere melk før kommersielt salg for å beskytte forbrukeren mot sykdomsfremkallende mikroorganismer. Fagfolk advarer mot å drikke rå melk, og påpeker risikoen for å bli syk av patogene bakterier som kan finnes i melken. I denne avhandlingen undersøker vi den potensielle risikoen det medfører å drikke upasteurisert melk fra Norge. I tillegg til å samle inn tankmelk- og speneprøver fra melkegårder i sørøst Norge, samlet vi også miljøprøver fra de samme gårdene for å kartlegge forekomst og for å identifisere potensielle mattrygghetsrisikoer i melkeproduksjonen. Alle prøvene ble analysert for de zoonotiske sykdomsfremkallende bakteriene Listeria monocytogenes, Campylobacter spp., og Shiga toksin-produserende Escherichia coli (STEC). Kyr kan være friske smittebærere av disse bakteriene, som dermed kan etablere et reservoar på gårdene. Bakteriene kan overføres fra gårdsmiljøet til melkekjeden og dermed utfordre mattryggheten. Disse bakteriene har forårsaket melkebårne sykdomsutbrudd over hele verden, også i Norge. Campylobacter spp. og STEC har lav infeksiøs dose, som vil si at man kan bli syk selv om man bare inntar et lavt antall bakterieceller. L. monocytogenes kan gi sykdommen listeriose, en av de mest alvorlige matbårne zoonotiske sykdommene vi har i den vestlige verden. Resultater fra denne oppgaven viser en høy forekomst av de tre patogenene i gårdsmiljøet. I tillegg var 7% av melkefiltrene vi testet positive for STEC, 13% positive for L. monocytogenes og 4% positive for Campylobacter spp.. Fire av STEC isolatene bar genet for Intimin, eae, som er ansett som en viktig virulensfaktor som øker sjansen for alvorlig sykdom. Ett av de eae-positive isolatene ble funnet i et melkefilter, noe som indikerer at norsk rå melk kan inneholde patogene STEC. For å videre vurdere risikoen for å bli syk av STEC fra rå melk undersøkte vi hvordan de fire eae-positive isolatene vokste i rå melk lagret ved forskjellige temperaturer. For alle isolatene økte antall bakterier etter lagring ved 8°C, og for et isolat var veksten signifikant. Etter lagring ved 6°C ble antallet bakterier redusert de første 24 timene, deretter stoppet reduksjonen i antall bakterier. Disse resultatene viser hvor viktig det er å ha stabil lav lagringstemperatur for rå melk, helst < 4°C. L. monocytogenes isolatene som ble samlet inn fra melkegårdene viste genetiske likheter med isolater samlet inn fra urbane og rurale miljøer rundt omkring i Norge. Derimot var kloner som dominerte i landbruksmiljøet forskjellige fra kliniske isolater og isolater fra matproduksjonslokaler. Videre så man at en klone kan persistere på en gård over tid og at melk kan kontamineres av L. monocytogenes kloner som er til stede i gårdsmiljøet. Til tross for små testvolum av tankmelken (25 mL) fant vi både STEC og Campylobacter spp. i melkeprøvene. 3% av tankmelkprøvene og speneprøvene var positive for Campylobacter spp. og ett STEC isolat ble funnet i tankmelk. L. monocytogenes ble ikke funnet direkte i melkeprøvene. Landbruket i Norge er i stadig utvikling der besetningene blir større, men færre. Melkebesetningene er midt i en overgang der tradisjonell oppstalling med melking på bås byttes ut med løsdriftssystemer og melkeroboter. Forekomsten av de tre patogenene funnet i denne studien var høyere i besetningene med løsdrift sammenliknet med besetningene som hadde melkekyrne oppstallet på bås. Pasteurisering er et viktig forebyggende tiltak for å beskytte konsumenter fra mikrobielle patogener, og i de fleste EU-land er kommersielt salg av rå melk juridisk begrenset. Denne studien viser at oppstallingstype kan påvirke nivåene av patogene bakterier i gårdsmiljøet og i rå melk. Inntak av rå melk kan eksponere forbruker for patogene bakterier som kan gi alvorlig sykdom, spesielt hos barn, eldre og personer med underliggende sykdommer. Resultatene underbygger viktigheten av å pasteurisere melk for å sikre mattryggheten, og at det er avgjørende å lagre rå melk ved kontinuerlig lave temperaturer for å forebygge vekst av zoonotiske patogener

    Inhomogeneous Enrichment of Radioactive Nuclei in the Galaxy: Deposition of Live 53 Mn, 60 Fe, 182 Hf, and 244 Pu into Deep-sea Archives. Surfing the Wave?

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    © 2023. The Author(s). Published by the American Astronomical Society. This article is license under a Creative Commons license. Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 licence. https://creativecommons.org/licenses/by/4.0/While modeling the galactic chemical evolution (GCE) of stable elements provides insights to the formation history of the Galaxy and the relative contributions of nucleosynthesis sites, modeling the evolution of short-lived radioisotopes (SLRs) can provide supplementary timing information on recent nucleosynthesis. To study the evolution of SLRs, we need to understand their spatial distribution. Using a three-dimensional GCE model, we investigated the evolution of four SLRs: 53Mn, 60Fe, 182Hf, and 244Pu with the aim of explaining detections of recent (within the last ≈1–20 Myr) deposition of live 53Mn, 60Fe, and 244Pu of extrasolar origin into deep-sea reservoirs. We find that core-collapse supernovae are the dominant propagation mechanism of SLRs in the Galaxy. This results in the simultaneous arrival of these four SLRs on Earth, although they could have been produced in different astrophysical sites, which can explain why live extrasolar 53Mn, 60Fe, and 244Pu are found within the same, or similar, layers of deep-sea sediments. We predict that 182Hf should also be found in such sediments at similar depths.Peer reviewe

    Tackling a Reorganization as an Interim Administrator

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    Chapter from the book Interim Leadership in Libraries: Building Relationships, Making Decisions, and Moving On, edited by Jennifer E. Knievel and Leslie J. Reynolds. ACRL, 202

    Recent Hong Kong cinema and the generic role of film noir in relation to the politics of identity and difference

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    This thesis identifies a connection in Hong Kong cinema with classical Hollywood film noir and examines what it will call a 'reinvestment' in film noir in recent films. It will show that this reinvestment is a discursive strategy that both engages the spectator-subject in the cinematic practice and disengages him or her from the hegemony of the discourse by decentring the narrative. The thesis argues that a cinematic practice has occurred in the recent reinvestment of film noir in Hong Kong, which restages the intertextual relay of the historical genre that gives rise to an expectation of ideas about social instability. The noir vision that is seen as related to the fixed categories of film narratives, characterizations and visual styles is reassessed in the course of the thesis using Derridian theory. The focus of analysis is the way in which the constitution of meanings is dependent on generic characteristics that are different. Key to the phenomenon is a film strategy that destabilizes, differs and defers the interpretation of crises-personal, social, political and/or cultural-by soliciting self-conscious re-reading of suffering, evil, fate, chance and fortune. It will be argued that such a strategy evokes the genre expectation as the film invokes a network of ideas regarding a world perceived by the audience in association with the noirish moods of claustrophobia, paranoia, despair and nihilism. The noir vision is thus mutated and transformed when the film device differs and defers the conception of the crises as tragic in nature by exposing the workings of the genre amalgamation and the ideological function of the cinematic discourse. Thus, noirishness becomes both an affect and an agent that contrives a self-reflexive re-reading of the tragic vision and of the conventional comprehension of reality within the discursive practice. The film strategy, as an agent that problematizes the film form and narrative, gives rise to what I call a politics of difference, which may also be understood as the Lyotardian 'language game' or a practice of 'pastiche' in Jameson's terminology. Under the influence of the film strategy, the spectator is enabled to negotiate his or her understanding of recent Hong Kong cinema diegetically and extra-diegetically by traversing different positions of cinematic identification. When the practice of genre amalgamation adopts the visual impact of the noirish film form, the film turns itself into a playing field of 'fatal' misrecognition or a site of question. Through cinematic identification and alienation from the identification, the spectator-subject is enabled to experience the misrecognition as the film slowly foregrounds the way in which the viewer's presence is implicated in the narrative. This thesis demonstrates that certain contemporary Hong Kong films introduce this selfconscious mode of explication and interpretation, which solicits the spectator to negotiate his or her subject-position in the course of viewing. The notions of identity and subjectivity under scrutiny will thus be reread. With reference to The Private Eye Blue, Swordsman II, City a/Glass and Happy Together, the thesis shall explore the ways in which the Hong Kong films enable and facilitate a negotiation of cultural identity

    Fresh start policies and small business activity: evidence from a natural experiment

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    No hay consenso en la literatura académica sobre si las leyes concursales para personas físicas deberían ser proacreedor o prodeudor para promover el emprendimiento y la actividad de las pequeñas empresas. Este documento contribuye a dicha literatura mediante el análisis del efecto de la introducción en España del mecanismo de segunda oportunidad (fresh start) en 2015 en el rendimiento de las microempresas españolas como un experimento natural, usando las empresas españolas de mayor dimensión y las empresas portuguesas como grupos de control. El estudio encuentra que dicha reforma aumentó sustancialmente la probabilidad tanto de que las microempresas españolas con problemas financieros soliciten concurso de acreedores (posiblemente para obtener la exoneración de una parte de las deudas del dueño de la empresa) como de que estas empresas salgan del mercado porque el mecanismo de segunda oportunidad requiere la liquidación del patrimonio inembargable del deudor. Además, la reforma fomentó la inversión en capital y la facturación de las microempresas, pero no tuvo un efecto claro en su empleo. Finalmente, promovió también la creación de nuevas microempresas, especialmente las dedicadas a la innovación y las pertenecientes a sectores con alta productividad.There is no consensus in the academic literature on whether personal bankruptcy laws should be creditor-friendly or debtor-friendly in order to promote entrepreneurship and small business activity. This paper contributes to that literature by analyzing the effect of the introduction of a fresh start policy in Spain in 2015 on the performance of micro-firms as a natural experiment, using Spanish non-micro firms and Portuguese firms as control groups. We find that the reform substantially increased both the probability of filing for bankruptcy by Spanish micro-firms in financial distress (arguably to seek discharge of part of the firm owner’s debt) and the probability of these firms exiting the market, as the fresh start policy requires the liquidation of the debtor’s non-exempt assets. In addition, the reform increased investment and turnover in micro-firms but had no effect on their employment. Finally, the reform also promoted the creation of new micro-firms, especially those involved in innovation activities and in sectors with high productivity

    NPS detection in prison: A systematic literature review of use, drug form, and analytical approaches

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    This paper presents a systematic literature review on the detection of new psychoactive substances (NPS) in prison settings. It includes the most frequently reported NPS classes, the routes and forms used for smuggling, and the methods employed to analyse biological and non-biological samples. The search was carried out using MEDLINE (EBSCO), Scopus (ELSEVIER), PubMed (NCBI), and Web of Science (Clarivate) databases, along with reports from the grey literature in line with the PRISMA-S guidelines. A total of 2708 records were identified, of which 50 met the inclusion criteria. Findings showed the most prevalent NPS class reported in prison was synthetic cannabinoids (SCs). The most frequently reported SCs in non-biological samples were 4F-MDMB-BINACA, MDMB-4en-PINACA, and 5F-ADB. These were smuggled mainly through the postal services deposited on paper or herbal matrices. Concentrations of SCs detected on seized paper ranged between 0.05 and 1.17 mg/cm2. The SCs most frequently reported in biological specimens (i.e., urine, blood, saliva, and wastewater) were 5F-MDMB-PICA, 4F-MDMB-BINACA, and MDMB-4en-PINACA. Concentrations of SCs reported in femoral blood and serum were 0.12–0.48 ng/ml and 34–17 ng/ml, respectively. Hyphenated techniques were predominantly employed and generally successful for the detection of NPS in biological (i.e., LC-HRMS/MS) and non-biological samples (i.e., LC-HRMS/MS and GC–MS). The onsite technique IMS showed promise for detecting SCs in various forms; however, immunoassays were not recommended. Future work should focus on accurate in-field detection of SCs deposited on paper and in urine and saliva to improve real-time decision-making, as well as wastewater and air monitoring for overall drug use trends
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