Distributed-memory parallelization of an explicit time-domain volume integral equation solver on Blue Gene/P

Two distributed-memory schemes for efficiently parallelizing the explicit marching-on in-time based solution of the time domain volume integral equation on the IBM Blue Gene/P platform are presented. In the first scheme, each processor stores the time history of all source fields and only the computationally dominant step of the tested field computations is distributed among processors. This scheme requires all-to-all global communications to update the time history of the source fields from the tested fields. In the second scheme, the source fields as well as all steps of the tested field computations are distributed among processors. This scheme requires sequential global communications to update the time history of the distributed source fields from the tested fields. Numerical results demonstrate that both schemes scale well on the IBM Blue Gene/P platform and the memory efficient second scheme allows for the characterization of transient wave interactions on composite structures discretized using three million spatial elements without an acceleration algorithm

Depression in patients with Type 2 Diabetes in Maltese primary care

Background: Type 2 diabetes and depression are two common chronic conditions affecting the Maltese population with significant and costly effects on health. Multiple studies have demonstrated a higher prevalence of depression in diabetic patients and a link with uncontrolled diabetes; however, despite this, depression is still not considered as important to chronic conditions in terms of the effects it has on health. -- Objectives: This study was conducted to estimate the prevalence of depression in type 2 diabetic patients in primary care and to study their associated risk factors. -- Method: A quantitative, cross-sectional, retrospective, descriptive study was performed among 400 participants with type 2 diabetes attending diabetes clinics within the public health centres in Malta. Patients completed a self-administered questionnaire to quantify depressive symptoms and to study patient and disease characteristics. Convenience sampling was used to collect the data. -- Results: Data analysis showed that the prevalence of depression is around 29.7% among type 2 diabetic patients. Younger diabetics, women, lower educational levels, unemployment, obesity, a family history of depression and uncontrolled diabetes were found to be associated with a higher risk of developing depressive symptoms. -- Conclusions: Screening for depression in type 2 diabetic patients is important due to the high prevalence and significant impact on health. Appropriate management can significantly improve the outcome of both conditions and consequently improve both health and quality of life.peer-reviewe

Developmental and gender trends in emotional literacy and interpersonal competence among Japanese children

This study explored cross-sectional gender and grade level trends in emotional literacy and interpersonal competence among 913 elementary and middle school students in Japan. Students were presented with two hypothetical scenarios involving mixed emotions and potential interpersonal dilemmas. Results indicated that older children possess greater emotional literacy when compared to younger children. Additionally, girls identified a greater number of emotions, were better able to identify mixed emotions, and were more likely to identify empathic interpersonal behaviours. These gender and grade level considerations may be incorporated into social-emotional learning curricula to enhance the utility and effectiveness of programs for diverse populations.peer-reviewe

Personal and family correlates to happiness amongst Italian children and pre-adolescents

This study examines how family functioning, the parent-child relationship and personal factors are related to happiness in 1549 children aged 7 to 14 years old (53% females) in Italy. Children and pre-adolescents completed a set of questionnaires on self-rated happiness, self-concept and loneliness. At least one of their parents filled in questionnaires on family functioning, attachment and their child’s happiness level. No gender differences were found in the direct measure of happiness, but younger participants were happier than older participants, according to both the children’s and parents’ evaluations. Happiness is influenced by positive self-concept, self-esteem and low levels of satisfaction but family functioning does not seem to play a major role. The clinical and social implications of the study are discussed.peer-reviewe

Special Libraries, December 1966

Volume 57, Issue 10https://scholarworks.sjsu.edu/sla_sl_1966/1009/thumbnail.jp

The Drosophila Inhibitor of Apoptosis (IAP) DIAP2 Is Dispensable for Cell Survival, Required for the Innate Immune Response to Gram-negative Bacterial Infection, and Can Be Negatively Regulated by the Reaper/Hid/Grim Family of IAP-binding Apoptosis Inducers

Many inhibitor of apoptosis (IAP) family proteins inhibit apoptosis. IAPs contain N-terminal baculovirus IAP repeat domains and a C-terminal RING ubiquitin ligase domain. Drosophila IAP DIAP1 is essential for the survival of many cells, protecting them from apoptosis by inhibiting active caspases. Apoptosis initiates when proteins such as Reaper, Hid, and Grim bind a surface groove in DIAP1 baculovirus IAP repeat domains via an N-terminal IAP-binding motif. This evolutionarily conserved interaction disrupts DIAP1-caspase interactions, unleashing apoptosis-inducing caspase activity. A second Drosophila IAP, DIAP2, also binds Rpr and Hid and inhibits apoptosis in multiple contexts when overexpressed. However, due to a lack of mutants, little is known about the normal functions of DIAP2. We report the generation of diap2 null mutants. These flies are viable and show no defects in developmental or stress-induced apoptosis. Instead, DIAP2 is required for the innate immune response to Gram-negative bacterial infection. DIAP2 promotes cytoplasmic cleavage and nuclear translocation of the NF-{kappa}B homolog Relish, and this requires the DIAP2 RING domain. Increasing the genetic dose of diap2 results in an increased immune response, whereas expression of Rpr or Hid results in down-regulation of DIAP2 protein levels. Together these observations suggest that DIAP2 can regulate immune signaling in a dose-dependent manner, and this can be regulated by IBM-containing proteins. Therefore, diap2 may identify a point of convergence between apoptosis and immune signaling pathways

The Effects of Childhood Social Support and Family Resiliency on Mental Health in Adulthood

The effect of social support on the overall health and quality of life in adulthood has been well documented particularly in chronic disease populations. Very few studies examined the relationships between childhood social support, family resiliency and mental health in adulthood in the community and among disadvantaged minority populations. We examined the role of social support and family resilience during childhood on subsequent mental health-related quality of life (HRQoL) in adulthood among racial/ethnic minorities. A needs assessment survey which was designed to explore health determinants and quality of life indicators using a community-based participatory research (CBPR) approach in a low-income community in Tampa was analyzed. Participants were predominantly low-income non-Hispanic black and Hispanic population (n=187). The outcome mental HRQoL was measured using the validated Centers for Disease Control and Prevention’s (CDC) “Healthy Days Measure” instrument. We utilized sequential multivariable logistic regression models to examine the independent effects of childhood social support and family resiliency on mental HRQoL in adulthood. Approximately 12.3% of study participants reported poor mental HRQoL (i.e. ≥14 unhealthy days due to mental health). Childhood social support and family resiliency were significant predictors of mental HRQoL in adulthood, after controlling for sociodemographic characteristics. Sleep and composite health issues in adulthood were also associated with mental HRQoL. Our analyses highlight an opportunity to promote mental health through support of interventions that improve positive family relationships and reduce the burden of chronic health issues among non-Hispanic black and Hispanic children

Special Libraries, February 1962

Volume 53, Issue 2https://scholarworks.sjsu.edu/sla_sl_1962/1001/thumbnail.jp