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Towards a Wearer-Centred Framework for Animal Biotelemetry
The emerging discipline of Animal-Computer Interaction (ACI) aims to understand the relation between animals and technology in naturalistic settings, to design technology that can support animals in different contexts and to develop user-centred research methods and frameworks that enable animals to take part in the design process as legitimate contributors [11]. Given existing interspecies differences and communication barriers, measuring the behaviour of animals involved in ACI research can be instrumental to achieving any or all of these aims, as a way of gauging the animalsā patterns, needs and preferences. Indeed, measuring behaviour is a common practice among ACI researchers, who take various approaches to this task [5,15,17,24]. In this respect, the use of biotelemetry devices such as VHF tags and GPS trackers, or bio-logging and environmental sensors has a significant potential [22].
At the same time, biotelemetry has been used for many years in many areas of biological research. Biotelemetry is used to improve the quality of physiological and behavioural data collected from animals and in an attempt to reduce researchersā intrusion in the animalsā habitat [2]. However, there is evidence that carrying biotelemetry tags may influence the bearerās physiology and behaviour [20]. Such impacts interfere with the validity of recorded data [14] and the welfare of individual animal wearers [1,3,13]. Neither of these effects are compatible with the animal-centred perspective advocated by ACI, on both scientific and ethical grounds. Our analysis of current body-attached device design and biotelemetry-enabled studies points to a general lack of wearer-centred perspective. To address these issues, we have developed a framework to inform the design of wearer-centred biotelemetry interventions, in order to support the implementation of animal-centred research methodologies and design solutions in ACI and other disciplines
Survey and Systematization of Secure Device Pairing
Secure Device Pairing (SDP) schemes have been developed to facilitate secure
communications among smart devices, both personal mobile devices and Internet
of Things (IoT) devices. Comparison and assessment of SDP schemes is
troublesome, because each scheme makes different assumptions about out-of-band
channels and adversary models, and are driven by their particular use-cases. A
conceptual model that facilitates meaningful comparison among SDP schemes is
missing. We provide such a model. In this article, we survey and analyze a wide
range of SDP schemes that are described in the literature, including a number
that have been adopted as standards. A system model and consistent terminology
for SDP schemes are built on the foundation of this survey, which are then used
to classify existing SDP schemes into a taxonomy that, for the first time,
enables their meaningful comparison and analysis.The existing SDP schemes are
analyzed using this model, revealing common systemic security weaknesses among
the surveyed SDP schemes that should become priority areas for future SDP
research, such as improving the integration of privacy requirements into the
design of SDP schemes. Our results allow SDP scheme designers to create schemes
that are more easily comparable with one another, and to assist the prevention
of persisting the weaknesses common to the current generation of SDP schemes.Comment: 34 pages, 5 figures, 3 tables, accepted at IEEE Communications
Surveys & Tutorials 2017 (Volume: PP, Issue: 99
Stigmergy in Web 2.0: a model for site dynamics
Building Web 2.0 sites does not necessarily ensure the success of the site. We aim to better understand what improves the success of a site by drawing insight from biologically inspired design patterns. Web 2.0 sites provide a mechanism for human interaction enabling powerful intercommunication between massive volumes of users. Early Web 2.0 site providers that were previously dominant are being succeeded by newer sites providing innovative social interaction mechanisms. Understanding what site traits contribute to this success drives research into Web sites mechanics using models to describe the associated social networking behaviour. Some of these models attempt to show how the volume of users provides a self-organising and self-contextualisation of content. One model describing coordinated environments is called stigmergy, a term originally describing coordinated insect behavior. This paper explores how exploiting stigmergy can provide a valuable mechanism for identifying and analysing online user behavior specifically when considering that user freedom of choice is restricted by the provided web site functionality. This will aid our building better collaborative Web sites improving the collaborative processes
Estimating snow cover from publicly available images
In this paper we study the problem of estimating snow cover in mountainous
regions, that is, the spatial extent of the earth surface covered by snow. We
argue that publicly available visual content, in the form of user generated
photographs and image feeds from outdoor webcams, can both be leveraged as
additional measurement sources, complementing existing ground, satellite and
airborne sensor data. To this end, we describe two content acquisition and
processing pipelines that are tailored to such sources, addressing the specific
challenges posed by each of them, e.g., identifying the mountain peaks,
filtering out images taken in bad weather conditions, handling varying
illumination conditions. The final outcome is summarized in a snow cover index,
which indicates for a specific mountain and day of the year, the fraction of
visible area covered by snow, possibly at different elevations. We created a
manually labelled dataset to assess the accuracy of the image snow covered area
estimation, achieving 90.0% precision at 91.1% recall. In addition, we show
that seasonal trends related to air temperature are captured by the snow cover
index.Comment: submitted to IEEE Transactions on Multimedi
Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex
VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vĪC16) induced less weight loss, fewer signs of illness and increased infiltration of leukocytes to the lungs compared with wild-type virus.
To understand C16ās mechanism of action, tandem affinity purification and mass spectrometry were used to identify C16 binding partners. This revealed that Ku70, Ku80 and PHD2 interact with C16 in cells.
Ku70 and Ku80 constitute the Ku heterodimer, a well characterised DNA repair complex. MEFs lacking Ku, or the other component of the DNA-dependent protein kinase (DNA-PK) complex, the catalytic subunit of DNA-PK (DNA-PKcs), were shown to be deficient in the upregulation of IRF-3-dependent genes such as Cxcl10, Il6 and Ifnb in response to transfection of DNA, but not poly (I:C). Furthermore, following infection of MEFs with VACV strain MVA the activation of Cxcl10 or Il6 transcription was dependent on DNA-PK. Therefore, DNA-PK is a DNA sensor capable of detecting poxvirus DNA and activating IRF-3-dependent innate immunity.
C16 inhibited the binding of Ku to DNA, and therefore inhibited DNA-mediated induction of Cxcl10 and Il-6 in MEFs. The role of C16 in vivo was also examined: infection with vĪC16 led to increased production of Cxcl10 and Il-6 following intranasal infection of mice compared with wild-type virus. C16 is therefore an inhibitor of DNA-PK-mediated DNA sensing and innate immune activation.
C16 was also shown to bind to PHD2, an enzyme involved in regulation of hypoxic signalling. VACV was found to activate the transcription of hypoxia-related genes, and C16 expression in cells was also capable of doing this. The role of hypoxic signalling in VACV infection remains poorly understood
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