Intelligent Systems for Sustainable Person-Centered Healthcare

This open access book establishes a dialog among the medical and intelligent system domains for igniting transition toward a sustainable and cost-effective healthcare. The Person-Centered Care (PCC) positions a person in the center of a healthcare system, instead of defining a patient as a set of diagnoses and treatment episodes. The PCC-based conceptual background triggers enhanced application of Artificial Intelligence, as it dissolves the limits of processing traditional medical data records, clinical tests and surveys. Enhanced knowledge for diagnosing, treatment and rehabilitation is captured and utilized by inclusion of data sources characterizing personal lifestyle, and health literacy, and it involves insights derived from smart ambience and wearables data, community networks, and the caregivers’ feedback. The book discusses intelligent systems and their applications for healthcare data analysis, decision making and process design tasks. The measurement systems and efficiency evaluation models analyze ability of intelligent healthcare system to monitor person health and improving quality of life

An investigation of analytics and business intelligence applications in improving healthcare organization performance: a mixed methods research

The healthcare ecosystem in the US is currently undergoing series of refinement and reformation due to the need to (i) improve quality of care and (ii) reduce cost. To achieve their key objective, healthcare organizations (HCOs) currently face a fundamental challenge: how to best use or optimize limited resources while providing better care and services to patients? The answer to this question might lie within HCO’s massive data and the ability to identify and apply appropriate analytics and business intelligence (A&BI) techniques and technologies to discern and extract relevant information and knowledge from that data. However, despite the increasing interest in the implementation and utilization of A&BI techniques and technologies by various organizations to improve operational efficiencies and financial performance, HCOs still lag behind other sectors in the adoption and use of A&BI capabilities. Motivated by the “data rich but information poor” syndrome currently facing HCOs, this dissertation applies a mixed method research–case study (interpretivist) and survey (positivist) – to investigate how healthcare organizations can leverage A&BI techniques and technologies to improve their overall performance. In achieving this objective, I illustrate an exemplar of how A&BI techniques and technologies can effectively be applied by specifically answering this high-level research question (RQ): How can A&BI techniques, methods, and technologies be developed and leveraged to improve performance in healthcare organizations? This high-level RQ has been broken down into four sub-questions that will be answered in two different studies in this dissertation. In the first study, I investigate what combination of A&BI techniques and technologies HCOs are currently applying to create value. This study was conducted by using content/literature analysis and case study methods in a large healthcare organization. The second study builds on the first study to investigate, using both interview and survey data, how A&BI capabilities can be developed, cultivated and nurtured as a core competency or capability that significantly helps improve healthcare organizations’ overall performance (such as cost reduction, quick access to providers and treatment, effective diagnostics, etc.). I found very novel and interesting results in both studies that not only address the research questions, but also provide significant theoretical and practical contributions. Major contributions of study 1 include: revising and remodeling of an outdated healthcare value chain (HCVC) framework that is more realistic and applicable to current care delivery practices in the healthcare industry and mapping of A&BI capabilities to the different domains of the revised HCVC framework. Study 2 provides theoretical contribution to the existing literature by conceptualizing and empirically validating A&BI capability as a third-order multi-dimension construct and its significant influence on performance

Intelligent Systems for Sustainable Person-Centered Healthcare

This open access book establishes a dialog among the medical and intelligent system domains for igniting transition toward a sustainable and cost-effective healthcare. The Person-Centered Care (PCC) positions a person in the center of a healthcare system, instead of defining a patient as a set of diagnoses and treatment episodes. The PCC-based conceptual background triggers enhanced application of Artificial Intelligence, as it dissolves the limits of processing traditional medical data records, clinical tests and surveys. Enhanced knowledge for diagnosing, treatment and rehabilitation is captured and utilized by inclusion of data sources characterizing personal lifestyle, and health literacy, and it involves insights derived from smart ambience and wearables data, community networks, and the caregivers’ feedback. The book discusses intelligent systems and their applications for healthcare data analysis, decision making and process design tasks. The measurement systems and efficiency evaluation models analyze ability of intelligent healthcare system to monitor person health and improving quality of life

New Fundamental Technologies in Data Mining

The progress of data mining technology and large public popularity establish a need for a comprehensive text on the subject. The series of books entitled by "Data Mining" address the need by presenting in-depth description of novel mining algorithms and many useful applications. In addition to understanding each section deeply, the two books present useful hints and strategies to solving problems in the following chapters. The contributing authors have highlighted many future research directions that will foster multi-disciplinary collaborations and hence will lead to significant development in the field of data mining

A Learning Health System for Radiation Oncology

The proposed research aims to address the challenges faced by clinical data science researchers in radiation oncology accessing, integrating, and analyzing heterogeneous data from various sources. The research presents a scalable intelligent infrastructure, called the Health Information Gateway and Exchange (HINGE), which captures and structures data from multiple sources into a knowledge base with semantically interlinked entities. This infrastructure enables researchers to mine novel associations and gather relevant knowledge for personalized clinical outcomes. The dissertation discusses the design framework and implementation of HINGE, which abstracts structured data from treatment planning systems, treatment management systems, and electronic health records. It utilizes disease-specific smart templates for capturing clinical information in a discrete manner. HINGE performs data extraction, aggregation, and quality and outcome assessment functions automatically, connecting seamlessly with local IT/medical infrastructure. Furthermore, the research presents a knowledge graph-based approach to map radiotherapy data to an ontology-based data repository using FAIR (Findable, Accessible, Interoperable, Reusable) concepts. This approach ensures that the data is easily discoverable and accessible for clinical decision support systems. The dissertation explores the ETL (Extract, Transform, Load) process, data model frameworks, ontologies, and provides a real-world clinical use case for this data mapping. To improve the efficiency of retrieving information from large clinical datasets, a search engine based on ontology-based keyword searching and synonym-based term matching tool was developed. The hierarchical nature of ontologies is leveraged to retrieve patient records based on parent and children classes. Additionally, patient similarity analysis is conducted using vector embedding models (Word2Vec, Doc2Vec, GloVe, and FastText) to identify similar patients based on text corpus creation methods. Results from the analysis using these models are presented. The implementation of a learning health system for predicting radiation pneumonitis following stereotactic body radiotherapy is also discussed. 3D convolutional neural networks (CNNs) are utilized with radiographic and dosimetric datasets to predict the likelihood of radiation pneumonitis. DenseNet-121 and ResNet-50 models are employed for this study, along with integrated gradient techniques to identify salient regions within the input 3D image dataset. The predictive performance of the 3D CNN models is evaluated based on clinical outcomes. Overall, the proposed Learning Health System provides a comprehensive solution for capturing, integrating, and analyzing heterogeneous data in a knowledge base. It offers researchers the ability to extract valuable insights and associations from diverse sources, ultimately leading to improved clinical outcomes. This work can serve as a model for implementing LHS in other medical specialties, advancing personalized and data-driven medicine

New Metropolitan Perspectives

​This open access book presents the outcomes of the symposium “NEW METROPOLITAN PERSPECTIVES,” held at Mediterranea University, Reggio Calabria, Italy on May 26–28, 2020. Addressing the challenge of Knowledge Dynamics and Innovation-driven Policies Towards Urban and Regional Transition, the book presents a multi-disciplinary debate on the new frontiers of strategic and spatial planning, economic programs and decision support tools in connection with urban–rural area networks and metropolitan centers. The respective papers focus on six major tracks: Innovation dynamics, smart cities and ICT; Urban regeneration, community-led practices and PPP; Local development, inland and urban areas in territorial cohesion strategies; Mobility, accessibility and infrastructures; Heritage, landscape and identity;and Risk management,environment and energy. The book also includes a Special Section on Rhegion United Nations 2020-2030. Given its scope, the book will benefit all researchers, practitioners and policymakers interested in issues concerning metropolitan and marginal areas

A geographic knowledge discovery approach to property valuation

This thesis involves an investigation of how knowledge discovery can be applied in the area Geographic Information Science. In particular, its application in the area of property valuation in order to reveal how different spatial entities and their interactions affect the price of the properties is explored. This approach is entirely data driven and does not require previous knowledge of the area applied. To demonstrate this process, a prototype system has been designed and implemented. It employs association rule mining and associative classification algorithms to uncover any existing inter-relationships and perform the valuation. Various algorithms that perform the above tasks have been proposed in the literature. The algorithm developed in this work is based on the Apriori algorithm. It has been however, extended with an implementation of a ‘Best Rule’ classification scheme based on the Classification Based on Associations (CBA) algorithm. For the modelling of geographic relationships a graph-theoretic approach has been employed. Graphs have been widely used as modelling tools within the geography domain, primarily for the investigation of network-type systems. In the current context, the graph reflects topological and metric relationships between the spatial entities depicting general spatial arrangements. An efficient graph search algorithm has been developed, based on the Djikstra shortest path algorithm that enables the investigation of relationships between spatial entities beyond first degree connectivity. A case study with data from three central London boroughs has been performed to validate the methodology and algorithms, and demonstrate its effectiveness for computer aided property valuation. In addition, through the case study, the influence of location in the value of properties in those boroughs has been examined. The results are encouraging as they demonstrate the effectiveness of the proposed methodology and algorithms, provided that the data is appropriately pre processed and is of high quality