4 research outputs found

    Micro/Nanofluidic Devices for Single Cell Analysis

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    An overview of multiple DoF magnetic actuated micro-robots.

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    International audienceThis paper reviews the state of the art of untethered, wirelessly actuated and controlled micro-robots. Research for such tools is being increasingly pursued to provide solutions for medical, biological and industrial applications. Indeed, due to their small size they o er both high velocity, and accessibility to tiny and clustered environments. These systems could be used for in vitro tasks on lab-on-chips in order to push and/or sort biological cells, or for in vivo tasks like minimally invasive surgery and could also be used in the micro-assembly of microcomponents. However, there are many constraints to actuating, manufacturing and controlling micro-robots, such as the impracticability of on-board sensors and actuators, common hysteresis phenomena and nonlinear behavior in the environment, and the high susceptibility to slight variations in the atmosphere like tiny dust or humidity. In this work, the major challenges that must be addressed are reviewed and some of the best performing multiple DoF micro-robots sized from tens to hundreds m are presented. The di erent magnetic micro-robot platforms are presented and compared. The actuation method as well as the control strategies are analyzed. The reviewed magnetic micro-robots highlight the ability of wireless actuation and show that high velocities can be reached. However, major issues on actuation and control must be overcome in order to perform complex micro-manipulation tasks

    Microfluidics and Bio-MEMS for Next Generation Healthcare.

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    Ph.D. Thesis. University of Hawaiʻi at Mānoa 2018

    Conception et commande de systèmes microrobotiques magnétiques en milieu ambiant

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    In the past few years, much attention has been given to autonomous systems of micrometric size. The small size of these robots, or particles, makes it impossible to embed their energy sources. Wireless systems for actuating and control, in particular through magnetic effects, have been proposed. They usually operate in a liquid environment. This environment is favored due to the drag force which stabilizes a system and therefore makes it easier to control. However, this medium comes with a major limitation to the moving speed of these particles. In order to fully exploit the potential for high speed actuation inherent to the low inertia of these small-sized particles, this thesis proposes the design and control of a microrobotic system dedicated to high speed actuation.The design choices, such increasing the magnetic force, using ferromagnetic particles and choosing to work in an ambient environment increases the displacement speed. However, the dry environment leads to adhesion issues between the particle and the surface of the working substrate, and lack of knowledge-based model. Various solutions are proposed in this thesis to overcome or reduce adhesion forces in this environment, from the coupled actuation of the magnetic, to the mechanical structuring of the surface of the substrate. A closed-loop control has also been integrated to increase the accuracy of the positioning and orientation of the particles. An approach to the synthesis and implementation of a proportional regulation is proposed for the two control parameters. The chosen experimental approach makes it possible to quantify the issues related to the ambient environment and bring systematic solutions to them.This work is but a first step in the integration of microrobotic systems in ambient environments, but it offers a control methodology, which is adapted to its specificities.Ces dernières années une attention particulière a été portée sur les systèmes autonomes de taille micrométrique. La taille de ces robots, ou particules, rend impossible l’embarquement d’énergie. Des systèmes d’actionnement et de contrôle à distance, notamment par effets magnétiques, ont été proposés. Ils évoluent généralement dans le milieu liquide. Ce milieu est privilégié en raison de la force de trainée qui stabilise les systèmes et simplifie donc leur contrôle. En revanche, ce milieu induit une limitation majeure sur la vitesse de déplacement de ces particules. Pour exploiter pleinement le potentiel d’actionnement rapide lié à la faible inertie de ces particules de petite taille, cette thèse propose la conception et la commande d’un système microrobotique dédié à l’actionnement haute vitesse. Les choix de conception, notamment l’augmentation de la force magnétique, l’utilisation de particules ferromagnétiques et le choix d’un environnement de travail en milieu ambiant permettent d’atteindre de grandes vitesses de déplacements. Cependant, le milieu ambiant pose des problématiques d’adhésion entre la particule et le substrat de travail et d’absence de modèle de connaissance. Des solutions sont proposées pour vaincre ou réduire les forces d’adhésion dans ce milieu, allant de l’actionnement en couple de la particule magnétique à la structuration mécanique du substrat. Une est également implémentée pour augmenter la précision du positionnement et de l’orientation des particules. Une approche permettant de synthétiser et d’implémenter une loi de régulation proportionnelle des deux paramètres de contrôle est proposée. L’approche expérimentale adoptée permet de quantifier les problématiques rencontrées dans le milieu ambiant et de proposer des solutions systématiques. Ce travail n’est qu’un premier pas dans l’intégration des systèmes microrobotiques en milieu ambiant, mais il fournit des méthodologies de contrôle adaptées à ses spécificités
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