15,874 research outputs found
Perspective: network-guided pattern formation of neural dynamics
The understanding of neural activity patterns is fundamentally linked to an
understanding of how the brain's network architecture shapes dynamical
processes. Established approaches rely mostly on deviations of a given network
from certain classes of random graphs. Hypotheses about the supposed role of
prominent topological features (for instance, the roles of modularity, network
motifs, or hierarchical network organization) are derived from these
deviations. An alternative strategy could be to study deviations of network
architectures from regular graphs (rings, lattices) and consider the
implications of such deviations for self-organized dynamic patterns on the
network. Following this strategy, we draw on the theory of spatiotemporal
pattern formation and propose a novel perspective for analyzing dynamics on
networks, by evaluating how the self-organized dynamics are confined by network
architecture to a small set of permissible collective states. In particular, we
discuss the role of prominent topological features of brain connectivity, such
as hubs, modules and hierarchy, in shaping activity patterns. We illustrate the
notion of network-guided pattern formation with numerical simulations and
outline how it can facilitate the understanding of neural dynamics
Neuro-memristive Circuits for Edge Computing: A review
The volume, veracity, variability, and velocity of data produced from the
ever-increasing network of sensors connected to Internet pose challenges for
power management, scalability, and sustainability of cloud computing
infrastructure. Increasing the data processing capability of edge computing
devices at lower power requirements can reduce several overheads for cloud
computing solutions. This paper provides the review of neuromorphic
CMOS-memristive architectures that can be integrated into edge computing
devices. We discuss why the neuromorphic architectures are useful for edge
devices and show the advantages, drawbacks and open problems in the field of
neuro-memristive circuits for edge computing
Fractals in the Nervous System: conceptual Implications for Theoretical Neuroscience
This essay is presented with two principal objectives in mind: first, to
document the prevalence of fractals at all levels of the nervous system, giving
credence to the notion of their functional relevance; and second, to draw
attention to the as yet still unresolved issues of the detailed relationships
among power law scaling, self-similarity, and self-organized criticality. As
regards criticality, I will document that it has become a pivotal reference
point in Neurodynamics. Furthermore, I will emphasize the not yet fully
appreciated significance of allometric control processes. For dynamic fractals,
I will assemble reasons for attributing to them the capacity to adapt task
execution to contextual changes across a range of scales. The final Section
consists of general reflections on the implications of the reviewed data, and
identifies what appear to be issues of fundamental importance for future
research in the rapidly evolving topic of this review
Complex networks: new trends for the analysis of brain connectivity
Today, the human brain can be studied as a whole. Electroencephalography,
magnetoencephalography, or functional magnetic resonance imaging techniques
provide functional connectivity patterns between different brain areas, and
during different pathological and cognitive neuro-dynamical states. In this
Tutorial we review novel complex networks approaches to unveil how brain
networks can efficiently manage local processing and global integration for the
transfer of information, while being at the same time capable of adapting to
satisfy changing neural demands.Comment: Tutorial paper to appear in the Int. J. Bif. Chao
Griffiths phases and localization in hierarchical modular networks
We study variants of hierarchical modular network models suggested by Kaiser
and Hilgetag [Frontiers in Neuroinformatics, 4 (2010) 8] to model functional
brain connectivity, using extensive simulations and quenched mean-field theory
(QMF), focusing on structures with a connection probability that decays
exponentially with the level index. Such networks can be embedded in
two-dimensional Euclidean space. We explore the dynamic behavior of the contact
process (CP) and threshold models on networks of this kind, including
hierarchical trees. While in the small-world networks originally proposed to
model brain connectivity, the topological heterogeneities are not strong enough
to induce deviations from mean-field behavior, we show that a Griffiths phase
can emerge under reduced connection probabilities, approaching the percolation
threshold. In this case the topological dimension of the networks is finite,
and extended regions of bursty, power-law dynamics are observed. Localization
in the steady state is also shown via QMF. We investigate the effects of link
asymmetry and coupling disorder, and show that localization can occur even in
small-world networks with high connectivity in case of link disorder.Comment: 18 pages, 20 figures, accepted version in Scientific Report
Retrieving Infinite Numbers of Patterns in a Spin-Glass Model of Immune Networks
The similarity between neural and immune networks has been known for decades,
but so far we did not understand the mechanism that allows the immune system,
unlike associative neural networks, to recall and execute a large number of
memorized defense strategies {\em in parallel}. The explanation turns out to
lie in the network topology. Neurons interact typically with a large number of
other neurons, whereas interactions among lymphocytes in immune networks are
very specific, and described by graphs with finite connectivity. In this paper
we use replica techniques to solve a statistical mechanical immune network
model with `coordinator branches' (T-cells) and `effector branches' (B-cells),
and show how the finite connectivity enables the system to manage an extensive
number of immune clones simultaneously, even above the percolation threshold.
The system exhibits only weak ergodicity breaking, so that both multiple
antigen defense and homeostasis can be accomplished.Comment: Editor's Choice 201
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