A multi-layer parametric approach to maximize the access probability of mobile networks

Next-generation mobile networks (5G) are defined to provide access in the framework of heterogeneous systems where it is crucial to have “always on” and “everywhere connectivity” capabilities. This is of fundamental importance even in 4G mobile systems, down to 3G and also Wi-Fi and WiMAX. In order to guarantee access to users with handheld devices equipped with multiple radio interfaces, an automated and reconfigurable tool for selecting the best network to be connected with is needed. This should be achieved by avoiding service outages. Current vertical handovers, i.e., switching from a network to another, are essentially based on power received levels and often do not avoid temporary service outages. We propose in this paper a procedure to access mobile networks by sensing multiple performance parameters related to networks available in the considered area. We target at maximizing the probability of accessing the wireless medium despite the technology used. We develop an algorithm, based on dynamic programming, able to select the most suitable network. We present the performance of the proposed algorithm both on the basis of computer simulations and on tests performed in an Arduino-based hardware platform

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

Depression is a complex, heterogeneous disorder and a leading contributor to the global burden of disease. Most previous research has focused on individual brain regions and genes contributing to depression. However, emerging evidence in humans and animal models suggests that dysregulated circuit function and gene expression across multiple brain regions drive depressive phenotypes. Here we performed RNA-sequencing on 4 brain regions from control animals and those susceptible or resilient to chronic social defeat stress at multiple time points. We employed an integrative network biology approach to identify transcriptional networks and key driver genes that regulate susceptibility to depressive-like symptoms. Further, we validated in vivo several key drivers and their associated transcriptional networks that regulate depression susceptibility and confirmed their functional significance at the levels of gene transcription, synaptic regulation and behavior. Our study reveals novel transcriptional networks that control stress susceptibility and offers fundamentally new leads for antidepressant drug discovery

XmoNet:a Fully Convolutional Network for Cross-Modality MR Image Inference

Magnetic resonance imaging (MRI) can generate multimodal scans with complementary contrast information, capturing various anatomical or functional properties of organs of interest. But whilst the acquisition of multiple modalities is favourable in clinical and research settings, it is hindered by a range of practical factors that include cost and imaging artefacts. We propose XmoNet, a deep-learning architecture based on fully convolutional networks (FCNs) that enables cross-modality MR image inference. This multiple branch architecture operates on various levels of image spatial resolutions, encoding rich feature hierarchies suited for this image generation task. We illustrate the utility of XmoNet in learning the mapping between heterogeneous T1- and T2-weighted MRI scans for accurate and realistic image synthesis in a preliminary analysis. Our findings support scaling the work to include larger samples and additional modalities

Heterogeneous V2V Communications in Multi-Link and Multi-RAT Vehicular Networks

Connected and automated vehicles will enable advanced traffic safety and efficiency applications thanks to the dynamic exchange of information between vehicles, and between vehicles and infrastructure nodes. Connected vehicles can utilize IEEE 802.11p for vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications. However, a widespread deployment of connected vehicles and the introduction of connected automated driving applications will notably increase the bandwidth and scalability requirements of vehicular networks. This paper proposes to address these challenges through the adoption of heterogeneous V2V communications in multi-link and multi-RAT vehicular networks. In particular, the paper proposes the first distributed (and decentralized) context-aware heterogeneous V2V communications algorithm that is technology and application agnostic, and that allows each vehicle to autonomously and dynamically select its communications technology taking into account its application requirements and the communication context conditions. This study demonstrates the potential of heterogeneous V2V communications, and the capability of the proposed algorithm to satisfy the vehicles' application requirements while approaching the estimated upper bound network capacity

Names, addresses and identities in ambient networks

Ambient Networks interconnect independent realms that may use different local network technologies and may belong to different administrative or legal entities. At the core of these advanced internetworking concepts is a flexible naming architecture based on dynamic indirections between names, addresses and identities. This paper gives an overview of the connectivity abstractions of Ambient Networks and then describes its naming architecture in detail, comparing and contrasting them to other related next-generation network architectures