Towards markerless orthopaedic navigation with intuitive Optical See-through Head-mounted displays

The potential of image-guided orthopaedic navigation to improve surgical outcomes has been well-recognised during the last two decades. According to the tracked pose of target bone, the anatomical information and preoperative plans are updated and displayed to surgeons, so that they can follow the guidance to reach the goal with higher accuracy, efficiency and reproducibility. Despite their success, current orthopaedic navigation systems have two main limitations: for target tracking, artificial markers have to be drilled into the bone and calibrated manually to the bone, which introduces the risk of additional harm to patients and increases operating complexity; for guidance visualisation, surgeons have to shift their attention from the patient to an external 2D monitor, which is disruptive and can be mentally stressful. Motivated by these limitations, this thesis explores the development of an intuitive, compact and reliable navigation system for orthopaedic surgery. To this end, conventional marker-based tracking is replaced by a novel markerless tracking algorithm, and the 2D display is replaced by a 3D holographic Optical see-through (OST) Head-mounted display (HMD) precisely calibrated to a user's perspective. Our markerless tracking, facilitated by a commercial RGBD camera, is achieved through deep learning-based bone segmentation followed by real-time pose registration. For robust segmentation, a new network is designed and efficiently augmented by a synthetic dataset. Our segmentation network outperforms the state-of-the-art regarding occlusion-robustness, device-agnostic behaviour, and target generalisability. For reliable pose registration, a novel Bounded Iterative Closest Point (BICP) workflow is proposed. The improved markerless tracking can achieve a clinically acceptable error of 0.95 deg and 2.17 mm according to a phantom test. OST displays allow ubiquitous enrichment of perceived real world with contextually blended virtual aids through semi-transparent glasses. They have been recognised as a suitable visual tool for surgical assistance, since they do not hinder the surgeon's natural eyesight and require no attention shift or perspective conversion. The OST calibration is crucial to ensure locational-coherent surgical guidance. Current calibration methods are either human error-prone or hardly applicable to commercial devices. To this end, we propose an offline camera-based calibration method that is highly accurate yet easy to implement in commercial products, and an online alignment-based refinement that is user-centric and robust against user error. The proposed methods are proven to be superior to other similar State-of- the-art (SOTA)s regarding calibration convenience and display accuracy. Motivated by the ambition to develop the world's first markerless OST navigation system, we integrated the developed markerless tracking and calibration scheme into a complete navigation workflow designed for femur drilling tasks during knee replacement surgery. We verify the usability of our designed OST system with an experienced orthopaedic surgeon by a cadaver study. Our test validates the potential of the proposed markerless navigation system for surgical assistance, although further improvement is required for clinical acceptance.Open Acces

Markerless Human Motion Analysis

Measuring and understanding human motion is crucial in several domains, ranging from neuroscience, to rehabilitation and sports biomechanics. Quantitative information about human motion is fundamental to study how our Central Nervous System controls and organizes movements to functionally evaluate motor performance and deficits. In the last decades, the research in this field has made considerable progress. State-of-the-art technologies that provide useful and accurate quantitative measures rely on marker-based systems. Unfortunately, markers are intrusive and their number and location must be determined a priori. Also, marker-based systems require expensive laboratory settings with several infrared cameras. This could modify the naturalness of a subject\u2019s movements and induce discomfort. Last, but not less important, they are computationally expensive in time and space. Recent advances on markerless pose estimation based on computer vision and deep neural networks are opening the possibility of adopting efficient video-based methods for extracting movement information from RGB video data. In this contest, this thesis presents original contributions to the following objectives: (i) the implementation of a video-based markerless pipeline to quantitatively characterize human motion; (ii) the assessment of its accuracy if compared with a gold standard marker-based system; (iii) the application of the pipeline to different domains in order to verify its versatility, with a special focus on the characterization of the motion of preterm infants and on gait analysis. With the proposed approach we highlight that, starting only from RGB videos and leveraging computer vision and machine learning techniques, it is possible to extract reliable information characterizing human motion comparable to that obtained with gold standard marker-based systems

Progress in industrial photogrammetry by means of markerless solutions

174 p.La siguiente tesis está enfocada al desarrollo y uso avanzado de metodologías fotogramétrica sin dianas en aplicaciones industriales. La fotogrametría es una técnica de medición óptica 3D que engloba múltiples configuraciones y aproximaciones. En este estudio se han desarrollado procedimientos de medición, modelos y estrategias de procesamiento de imagen que van más allá que la fotogrametría convencional y buscan el emplear soluciones de otros campos de la visión artificial en aplicaciones industriales. Mientras que la fotogrametría industrial requiere emplear dianas artificiales para definir los puntos o elementos de interés, esta tesis contempla la reducción e incluso la eliminación de las dianas tanto pasivas como activas como alternativas prácticas. La mayoría de los sistemas de medida utilizan las dianas tanto para definir los puntos de control, relacionar las distintas perspectivas, obtener precisión, así como para automatizar las medidas. Aunque en muchas situaciones el empleo de dianas no sea restrictivo existen aplicaciones industriales donde su empleo condiciona y restringe considerablemente los procedimientos de medida empleados en la inspección. Un claro ejemplo es la verificación y control de calidad de piezas seriadas, o la medición y seguimiento de elementos prismáticos relacionados con un sistema de referencia determinado. Es en este punto donde la fotogrametría sin dianas puede combinarse o complementarse con soluciones tradicionales para tratar de mejorar las prestaciones actuales

AFFECT-PRESERVING VISUAL PRIVACY PROTECTION

The prevalence of wireless networks and the convenience of mobile cameras enable many new video applications other than security and entertainment. From behavioral diagnosis to wellness monitoring, cameras are increasing used for observations in various educational and medical settings. Videos collected for such applications are considered protected health information under privacy laws in many countries. Visual privacy protection techniques, such as blurring or object removal, can be used to mitigate privacy concern, but they also obliterate important visual cues of affect and social behaviors that are crucial for the target applications. In this dissertation, we propose to balance the privacy protection and the utility of the data by preserving the privacy-insensitive information, such as pose and expression, which is useful in many applications involving visual understanding. The Intellectual Merits of the dissertation include a novel framework for visual privacy protection by manipulating facial image and body shape of individuals, which: (1) is able to conceal the identity of individuals; (2) provide a way to preserve the utility of the data, such as expression and pose information; (3) balance the utility of the data and capacity of the privacy protection. The Broader Impacts of the dissertation focus on the significance of privacy protection on visual data, and the inadequacy of current privacy enhancing technologies in preserving affect and behavioral attributes of the visual content, which are highly useful for behavior observation in educational and medical settings. This work in this dissertation represents one of the first attempts in achieving both goals simultaneously

Fast and Robust Hand Tracking Using Detection-Guided Optimization

Markerless tracking of hands and fingers is a promising enabler for human-computer interaction. However, adoption has been limited because of tracking inaccuracies, incomplete coverage of motions, low framerate, complex camera setups, and high computational requirements. In this paper, we present a fast method for accurately tracking rapid and complex articulations of the hand using a single depth camera. Our algorithm uses a novel detection-guided optimization strategy that increases the robustness and speed of pose estimation. In the detection step, a randomized decision forest classifies pixels into parts of the hand. In the optimization step, a novel objective function combines the detected part labels and a Gaussian mixture representation of the depth to estimate a pose that best fits the depth. Our approach needs comparably less computational resources which makes it extremely fast (50 fps without GPU support). The approach also supports varying static, or moving, camera-to-scene arrangements. We show the benefits of our method by evaluating on public datasets and comparing against previous work