Computer memories: the history of computer form

This paper looks at the computer as a truly global form. The similar beige boxes found in offices across the world are analysed from the perspective of design history rather than that of the history of science and technology. Through the exploration of an archive of computer manufacturer's catalogues and concurrent design texts, this paper examines the changes that have occurred in the production and consumption of the computer in the context of the workplace, from its inception as a room-sized mainframe operated through a console of flashing lights, to the personal computer as a 'universal' form, reproduced by many manufacturers. It shows how the computer in the past has been as diverse as any other product, and asks how and why it now appears as a standardised, sanitised object. In doing so our relationship with the office computer, past and present is explored, revealing a complex history of vicissitude.</p

From Structure to Function in Open Ionic Channels

We consider a simple working hypothesis that all permeation properties of open ionic channels can be predicted by understanding electrodiffusion in fixed structures, without invoking conformation changes, or changes in chemical bonds. We know, of course, that ions can bind to specific protein structures, and that this binding is not easily described by the traditional electrostatic equations of physics textbooks, that describe average electric fields, the so-called `mean field'. The question is which specific properties can be explained just by mean field electrostatics and which cannot. I believe the best way to uncover the specific chemical properties of channels is to invoke them as little as possible, seeking to explain with mean field electrostatics first. Then, when phenomena appear that cannot be described that way, by the mean field alone, we turn to chemically specific explanations, seeking the appropriate tools (of electrochemistry, Langevin, or molecular dynamics, for example) to understand them. In this spirit, we turn now to the structure of open ionic channels, apply the laws of electrodiffusion to them, and see how many of their properties we can predict just that way.Comment: Nearly final version of publicatio

Early Development of Total Hip Replacement

Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2007. ©The Trustee of the Wellcome Trust, London, 2007. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Annotated and edited transcript of a Witness Seminar held on 14 March 2006. Introduction by Dr Francis Neary and Professor John Pickstone,Total hip replacement effectively began in the UK in 1938 and has led to widely used, commercially successful, mass-produced devices that relieve pain for an ever increasing period. The Witness Seminar, chaired by Mr Alan Lettin, discussed the remarkable postwar collaboration of British surgeons, engineers and manufacturing firms in the development of efficient alloys, surgical procedures, instruments and the implementation of clean, bacteria-reduced air in enclosed operating theatres, as illustrated by successful prostheses and techniques developed in Norwich (Kenneth McKee), Wrightington (Sir John Charnley), Stanmore (John Scales), Redhill (Peter Ring), and Exeter (Robin Ling and Clive Lee). Early failures - such as loosening from infection, osteolysis, and wear debris - stimulated the search for improved materials and fixation methods, as well as the addition of antibiotics to bone cement to reduce infection. National hip registers that record the survival of different implants were adopted in Europe in the 1970s (2003 in the UK), and they pinpoint the successful devices, as measured by survival and low rates of revision. An introduction to the volume by Dr Francis Neary and Professor John Pickstone, and appendices on materials by Professor Alan Swanson; on international standards by Mr Victor Wheble; and of details of selected prosthesis supplement the transcript. Contributors include: Lady Charnley, the late Mr Harry Craven, Mr Graham Deane, Professor Duncan Dowson, Mr Reg Elson, Dr Alex Faulkner, Professor Michael Freeman, Mrs Phyllis Hampson, Mr Kevin Hardinge, Mr Mike Heywood-Waddington, Mr John Kirkup, Mr Krishna (Ravi) Kunzru, Miss Betty Lee, Mr Alan Lettin (chair), Mr John Older, Mr John Read, Mr Peter Ring, Mr Ian Stephen, Mr Malcolm Swann, Professor Alan Swanson, Sir Rodney Sweetnam, Mr Keith Tucker, Mr Victor Wheble and Professor Michael Wroblewski. Reynolds L A, Tansey E M. (eds) (2007) Early development of total hip replacement, Wellcome Witnesses to Twentieth Century Medicine, vol. 29. London: The Wellcome Trust Centre for the History of Medicine at UCL.The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183

The Animal Ethics of Temple Grandin: A Protectionist Analysis

This article brings animal protection theory to bear on Temple Grandin’s work, in her capacity both as a designer of slaughter facilities and as an advocate for omnivorism. Animal protection is a better term for what is often termed animal rights, given that many of the theories grouped under the animal rights label do not extend the concept of rights to animals. I outline the nature of Grandin’s system of humane slaughter as it pertains to cattle. I then outline four arguments Grandin has made defending meat-eating. On a protection-based approach, I argue, Grandin’s system of slaughter is superior to its traditional counterpart. Grandin’s success as a designer of humane slaughterhouses however is not matched by any corresponding success in offering a moral defence of meat-eating. Despite, or perhaps because of, the popularity of her work, Grandin’s arguments for continuing to eat animals are noteworthy only in how disappointing and rudimentary they are. If we can thank Grandin for making a difference in the lives of millions of farm animals, her work can also be criticized for not engaging the moral status of animals with the depth and rigor that it deserves

A Graphic design primer resources for educators

This thesis examines current methods and trends in graphic design education. It focuses on the improvement of graphic design education by helping educators better understand the graphic design discipline, describing important factors in a design education, and the needs of the graphic design student. The focus is on the first year of graphic design study, and includes a sample textbook designed by the thesis author for first-year graphic arts students