1,412 research outputs found

    Causality, Information and Biological Computation: An algorithmic software approach to life, disease and the immune system

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    Biology has taken strong steps towards becoming a computer science aiming at reprogramming nature after the realisation that nature herself has reprogrammed organisms by harnessing the power of natural selection and the digital prescriptive nature of replicating DNA. Here we further unpack ideas related to computability, algorithmic information theory and software engineering, in the context of the extent to which biology can be (re)programmed, and with how we may go about doing so in a more systematic way with all the tools and concepts offered by theoretical computer science in a translation exercise from computing to molecular biology and back. These concepts provide a means to a hierarchical organization thereby blurring previously clear-cut lines between concepts like matter and life, or between tumour types that are otherwise taken as different and may not have however a different cause. This does not diminish the properties of life or make its components and functions less interesting. On the contrary, this approach makes for a more encompassing and integrated view of nature, one that subsumes observer and observed within the same system, and can generate new perspectives and tools with which to view complex diseases like cancer, approaching them afresh from a software-engineering viewpoint that casts evolution in the role of programmer, cells as computing machines, DNA and genes as instructions and computer programs, viruses as hacking devices, the immune system as a software debugging tool, and diseases as an information-theoretic battlefield where all these forces deploy. We show how information theory and algorithmic programming may explain fundamental mechanisms of life and death.Comment: 30 pages, 8 figures. Invited chapter contribution to Information and Causality: From Matter to Life. Sara I. Walker, Paul C.W. Davies and George Ellis (eds.), Cambridge University Pres

    Human Computation and Convergence

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    Humans are the most effective integrators and producers of information, directly and through the use of information-processing inventions. As these inventions become increasingly sophisticated, the substantive role of humans in processing information will tend toward capabilities that derive from our most complex cognitive processes, e.g., abstraction, creativity, and applied world knowledge. Through the advancement of human computation - methods that leverage the respective strengths of humans and machines in distributed information-processing systems - formerly discrete processes will combine synergistically into increasingly integrated and complex information processing systems. These new, collective systems will exhibit an unprecedented degree of predictive accuracy in modeling physical and techno-social processes, and may ultimately coalesce into a single unified predictive organism, with the capacity to address societies most wicked problems and achieve planetary homeostasis.Comment: Pre-publication draft of chapter. 24 pages, 3 figures; added references to page 1 and 3, and corrected typ

    Robotic ubiquitous cognitive ecology for smart homes

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    Robotic ecologies are networks of heterogeneous robotic devices pervasively embedded in everyday environments, where they cooperate to perform complex tasks. While their potential makes them increasingly popular, one fundamental problem is how to make them both autonomous and adaptive, so as to reduce the amount of preparation, pre-programming and human supervision that they require in real world applications. The project RUBICON develops learning solutions which yield cheaper, adaptive and efficient coordination of robotic ecologies. The approach we pursue builds upon a unique combination of methods from cognitive robotics, machine learning, planning and agent- based control, and wireless sensor networks. This paper illustrates the innovations advanced by RUBICON in each of these fronts before describing how the resulting techniques have been integrated and applied to a smart home scenario. The resulting system is able to provide useful services and pro-actively assist the users in their activities. RUBICON learns through an incremental and progressive approach driven by the feed- back received from its own activities and from the user, while also self-organizing the manner in which it uses available sensors, actuators and other functional components in the process. This paper summarises some of the lessons learned by adopting such an approach and outlines promising directions for future work

    Bio-inspired computation for big data fusion, storage, processing, learning and visualization: state of the art and future directions

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    This overview gravitates on research achievements that have recently emerged from the confluence between Big Data technologies and bio-inspired computation. A manifold of reasons can be identified for the profitable synergy between these two paradigms, all rooted on the adaptability, intelligence and robustness that biologically inspired principles can provide to technologies aimed to manage, retrieve, fuse and process Big Data efficiently. We delve into this research field by first analyzing in depth the existing literature, with a focus on advances reported in the last few years. This prior literature analysis is complemented by an identification of the new trends and open challenges in Big Data that remain unsolved to date, and that can be effectively addressed by bio-inspired algorithms. As a second contribution, this work elaborates on how bio-inspired algorithms need to be adapted for their use in a Big Data context, in which data fusion becomes crucial as a previous step to allow processing and mining several and potentially heterogeneous data sources. This analysis allows exploring and comparing the scope and efficiency of existing approaches across different problems and domains, with the purpose of identifying new potential applications and research niches. Finally, this survey highlights open issues that remain unsolved to date in this research avenue, alongside a prescription of recommendations for future research.This work has received funding support from the Basque Government (Eusko Jaurlaritza) through the Consolidated Research Group MATHMODE (IT1294-19), EMAITEK and ELK ARTEK programs. D. Camacho also acknowledges support from the Spanish Ministry of Science and Education under PID2020-117263GB-100 grant (FightDIS), the Comunidad Autonoma de Madrid under S2018/TCS-4566 grant (CYNAMON), and the CHIST ERA 2017 BDSI PACMEL Project (PCI2019-103623, Spain)
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