259 research outputs found

    Relative Identity and Ideal Art: The Pirandello Conflict and Its Political Analogy

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    Daily newspaper from Sapulpa, Oklahoma that includes local, state, and national news along with advertising

    Review of "Ludica" by Riccardo Pelizzo and Mark Nowacki

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    The philosophy of Pío Baroja with special reference to the influence of Nietzsche

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    Thesis (M.A.)--University of Kansas, Spanish and Portuguese, 1932

    Review of "Ludica" by Riccardo Pelizzo and Mark Nowacki

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    From December 1999 until July 2001, a phase I dose escalation study was performed with (186)Re-labeled bivatuzumab, a humanized monoclonal antibody against CD44v6, on patients with inoperable recurrent or metastatic head and neck cancer. The aim of the trial was to assess the safety and tolerability of intravenously administered (186)Re-bivatuzumab and to determine the maximum tolerated dose (MTD) of (186)Re-bivatuzumab. The data were also used for dosimetric analysis of the treated patients. Dosimetry is used to estimate the absorbed doses by nontarget organs, as well as by tumors. It can also help to explain toxicity that is observed and to predict organs at risk because of the therapy given. METHODS: Whole-body scintigraphy was used to draw regions around sites or organs of interest. Residence times in these organs and sites were calculated and entered into the MIRDOSE3 program, to obtain absorbed doses in all target organs except for red marrow. The red marrow dose was calculated using a blood-derived method. Twenty-one studies on 18 patients, 5 female and 16 male, were used for dosimetry. RESULTS: The mean red marrow doses were 0.49 +/- 0.03 mGy/MBq for men and 0.64 +/- 0.03 mGy/MBq for women. The normal organ with the highest absorbed dose appeared to be the kidney (mean dose, 1.61 +/- 0.75 mGy/MBq in men and 2.15 +/- 0.95 mGy/MBq in women; maximum kidney dose in all patients, 11 Gy), but the doses absorbed are not expected to lead to renal toxicity. Other organs with doses exceeding 0.5 mGy/MBq were the lungs, the spleen, the heart, the liver, the bones, and the testes. The doses delivered to the tumor, recalculated to the MTD level of 1.85 GBq/m(2), ranged from 3.8 to 76.4 Gy, with a median of 12.4 Gy. A good correlation was found between platelet and white blood cell counts and the administered amount of activity per kilogram of body weight (r = -0.79). CONCLUSION: Dosimetric analysis of the data revealed that the range of doses to normal organs seems to be well within acceptable and safe limits. Tumor doses ranged from 4 to 76 Gy. Given the acceptable tumor doses, (186)Re-labeled bivatuzumab could be a good candidate for future adjuvant radioimmunotherapy in patients with minimal residual disease

    Personality Temperament, Character and Behavior

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    Existing classifications of temperament characters personality types and ways of behaviour are the disputable issues of the present-day scientific world The origins of the classifications rise from the ancient philosophy and medicine in China and India VIII BCE Greece V BCE Rome II century AD England and Germany I century USA and Russia century Tremendous amount of the classifications were worked out all over the world and not all of them withstood the test of time The references to Hippocrates and Claudius Galenus classifications occur chiefly which are tangential with regard to mentality and psychic setup and based on humoralism humorism Great empirical and experimental materials have been accumulated in scientific history without harmonious systematization in view of the absence of the integrated international system of classification that is the factor restraining the further development of typology There were curious incidents during typology march Fourier described three hundred characters for instance Unfortunately any ordinary person could not be able to remember all these descriptions Since then researches finding and admission of the optimum types became the task of paramount importance for the scientist

    Charms, Prayers, Concoctions, and Pilgrimages: The Effectiveness of Learned Medicine versus Common Medicine During the Medieval Ages

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    Medical history has recently been growing as a field of study because of the strong advancements occurring in medicine. Many have studied the progression of modern medicine from Ancient History through to the Renaissance, but little attention has been given to the true effectiveness of medicine right before it was transformed within the 16th and 17th centuries. In analyzing the success of European medieval medicine on the patient, we can start to understand the evolution of healing since the first recitings of the Hippocratic Oath. Through the use of popular texts like Stere Htt Well, The Mirror of Jaume Roig, and The Medieval Women\u27s Guide to Health, this research will try to decipher whether the learned physicians or the common healers in the medieval ages had the most effective practices towards healing. The thoughts of other historians are split between whether or not the practices (religion, astrology, humorism, and midwifery) were actually helpful for the ill. It is through the documented opinions of the patient for us to find the truth. Although it is difficult to know whether or not the judgments from patients have been altered by bias, there are still efforts being made to find the true opinions hidden in the contracts that still survive. Sadly, many of these voices cannot be recaptured. With the Bolognese contracts used in this argument along with the texts mentioned above, I propose that both the learned and the common healers had effective practices for healing the sick
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