3 research outputs found
Management Matters
New indications of managerial innovations are created and then used to show that changes in organizational technologies are an important source of economic growth. Specifically, the analysis demonstrates that, first, in response to a positive managerial technology shock, output, productivity and hours significantly increase in the short run, second, these types of innovations are as important as non-managerial ones in explaining movements in these variables at business cycle frequencies, and, third, product and process innovations promote the development of new managerial techniques.Business Cycles; Productivity; Management techniques; Technical Change
Multiple Primary Cancers in Patients with Breast and Skin Cancer
The extent of the problem
The number of cancer survivors has been increasing dramatically and is expected to keep
growing in the near future. In the Netherlands, a 38% increase of cancer survivors is
estimated from 2005 to 2015, representing an increase from 500,000 to 692,000 (ex-)
patients in this period.1 It is well known that individuals who suffered from cancer exhibit a
20% higher risk of subsequent primary malignancies.2 Thus, as the number of cancer
survivors increases, the number of patients with multiple primary cancers will increase as
well. Because cancer is more frequent among the elderly, the ageing of the Dutch population
will cause a further increase in the number of cases with multiple cancers: Only 5%-12% of
cancer patients aged 50-64 were previously diagnosed with cancer, versus 12%-26% of
those aged over 803. Other forces, including increased awareness of (second) malignancies,
the higher use and sensitivity of diagnostic/detection methods, and the recent improvements
in cancer treatment and survival will further lead to higher prevalence of multiple cancers.
Cancer survivors who develop a second malignancy have a higher risk of dying4 and
experience a worsening in their quality of life. Thus, increased interest in second cancer from
the epidemiological and clinical perspective is highly relevant