Toward a successful clinical neuroproteomics : the 11th HUPO Brain Proteome Project Workshop 3 March, 2009, Kolymbari, Greece

The HUPO Brain Proteome Project (HUPO BPP) held its 11th workshop in Kolymbari on March 3, 2009. The principal aim of this project is to obtain a better understanding of neurodiseases and ageing, with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss sub-project progress in the clinical neuroproteomics of human or mouse models of Alzheimer's and Parkinson's disease, and to define the needs and guidelines required for more advanced proteomics approaches. With the election of new steering committees, the members of the HUPO BPP elaborated an actual plan promoting activities, outcomes, and future directions of the HUPO BPP to acquire new funding and new participants

An interval-valued intuitionistic fuzzy multiattribute group decision making framework with incomplete preference over alternatives

This article proposes a framework to handle multiattribute group decision making problems with incomplete pairwise comparison preference over decision alternatives where qualitative and quantitative attribute values are furnished as linguistic variables and crisp numbers, respectively. Attribute assessments are then converted to interval-valued intuitionistic fuzzy numbers (IVIFNs) to characterize fuzziness and uncertainty in the evaluation process. Group consistency and inconsistency indices are introduced for incomplete pairwise comparison preference relations on alternatives provided by the decision-makers (DMs). By minimizing the group inconsistency index under certain constraints, an auxiliary linear programming model is developed to obtain unified attribute weights and an interval-valued intuitionistic fuzzy positive ideal solution (IVIFPIS). Attribute weights are subsequently employed to calculate distances between alternatives and the IVIFPIS for ranking alternatives. An illustrative example is provided to demonstrate the applicability and effectiveness of this method

Incomplete interval fuzzy preference relations and their applications

This paper investigates incomplete interval fuzzy preference relations. A characterization, which is proposed by Herrera-Viedma et al. (2004), of the additive consistency property of the fuzzy preference relations is extended to a more general case. This property is further generalized to interval fuzzy preference relations (IFPRs) based on additive transitivity. Subsequently, we examine how to characterize IFPR. Using these new characterizations, we propose a method to construct an additive consistent IFPR from a set of n − 1 preference data and an estimation algorithm for acceptable incomplete IFPRs with more known elements. Numerical examples are provided to illustrate the effectiveness and practicality of the solution process

Ordering based decision making: a survey

Decision making is the crucial step in many real applications such as organization management, financial planning, products evaluation and recommendation. Rational decision making is to select an alternative from a set of different ones which has the best utility (i.e., maximally satisfies given criteria, objectives, or preferences). In many cases, decision making is to order alternatives and select one or a few among the top of the ranking. Orderings provide a natural and effective way for representing indeterminate situations which are pervasive in commonsense reasoning. Ordering based decision making is then to find the suitable method for evaluating candidates or ranking alternatives based on provided ordinal information and criteria, and this in many cases is to rank alternatives based on qualitative ordering information. In this paper, we discuss the importance and research aspects of ordering based decision making, and review the existing ordering based decision making theories and methods along with some future research directions

Trust Based Consensus Model for Social Network in an Incomplete Linguistic Information Context

A theoretical framework to consensus building within a networked social group is put forward. This article investigates a trust based estimation and aggregation methods as part of a visual consensus model for multiple criteria group decision making with incomplete linguistic information. A novel trust propagation method is proposed to derive trust relationship from an incomplete connected trust network and the trust score induced order weighted averaging operator is presented to aggregate the orthopairs of trust/distrust values obtained from different trust paths. Then, the concept of relative trust score is defined, whose use is twofold: (1) to estimate the unknown preference values and (2) as a reliable source to determine experts' weights. A visual feedback process is developed to provide experts with graphical representations of their consensus status within the group as well as to identify the alternatives and preference values that should be reconsidered for changing in the subsequent consensus round. The feedback process also includes a recommendation mechanism to provide advice to those experts that are identified as contributing less to consensus on how to change their identified preference values. It is proved that the implementation of the visual feedback mechanism guarantees the convergence of the consensus reaching process

Uninorm trust propagation and aggregation methods for group decision making in social network with four tuples information

The file attached to this record is the authors accepted version. The publisher's final version of record can be found by following the DOI link below.A novel social network based group decision making (SN-GDM) model with experts' weights not provided beforehand and with the following four tuple information: trust; distrust; hesitancy; and inconsistency, is introduced. The concepts of trust score (TS) and knowledge degree (KD) are de ned and combined into a trust order space. Then, a strict trust ranking order relation of trust function values (TFs) is built in which TS and KD play a similar role to the mean and the variance in Statistics. After the operational laws of TFs for uninorm operators are built, the uninorm propagation operator is investigated. It can propagate through a network both trust and distrust information simultaneously and therefore it prevents the loss of trust information in the propagating process. When an indirect trust relationship is built, the uninorm trust weighted average (UTWA) operator and the uninorm trust ordered weighted average (UTOWA) operator are de ned and used to aggregate individual trust relationship and to obtain their associated ranking order relation. Hence, the most trusted expert is distinguished from the group, and the weights of experts are determined in a reasonable way: the higher an expert is trusted the more importance value is assigned to the expert. Therefore, the novelty of the proposed SN-GDM is that it can use indirect trust relationship via trusted third partners (TTPs) as a reliable resource to determine experts' weights. Finally, the individual trust decision making matrices are aggregated into a collective one and the alternative with the highest trust order relation is selected as the best one