Robust semi-automated path extraction for visualising stenosis of the coronary arteries

Computed tomography angiography (CTA) is useful for diagnosing and planning treatment of heart disease. However, contrast agent in surrounding structures (such as the aorta and left ventricle) makes 3-D visualisation of the coronary arteries difficult. This paper presents a composite method employing segmentation and volume rendering to overcome this issue. A key contribution is a novel Fast Marching minimal path cost function for vessel centreline extraction. The resultant centreline is used to compute a measure of vessel lumen, which indicates the degree of stenosis (narrowing of a vessel). Two volume visualisation techniques are presented which utilise the segmented arteries and lumen measure. The system is evaluated and demonstrated using synthetic and clinically obtained datasets

Multiscale Astronomical Image Processing Based on Nonlinear Partial Differential Equations

Astronomical applications of recent advances in the field of nonastronomical image processing are presented. These innovative methods, applied to multiscale astronomical images, increase signal-to-noise ratio, do not smear point sources or extended diffuse structures, and are thus a highly useful preliminary step for detection of different features including point sources, smoothing of clumpy data, and removal of contaminants from background maps. We show how the new methods, combined with other algorithms of image processing, unveil fine diffuse structures while at the same time enhance detection of localized objects, thus facilitating interactive morphology studies and paving the way for the automated recognition and classification of different features. We have also developed a new application framework for astronomical image processing that implements some recent advances made in computer vision and modern image processing, along with original algorithms based on nonlinear partial differential equations. The framework enables the user to easily set up and customize an image-processing pipeline interactively; it has various common and new visualization features and provides access to many astronomy data archives. Altogether, the results presented here demonstrate the first implementation of a novel synergistic approach based on integration of image processing, image visualization, and image quality assessment