Computational Modeling Approaches For Task Analysis In Robotic-Assisted Surgery

Surgery is continuously subject to technological innovations including the introduction of robotic surgical devices. The ultimate goal is to program the surgical robot to perform certain difficult or complex surgical tasks in an autonomous manner. The feasibility of current robotic surgery systems to record quantitative motion and video data motivates developing descriptive mathematical models to recognize, classify and analyze surgical tasks. Recent advances in machine learning research for uncovering concealed patterns in huge data sets, like kinematic and video data, offer a possibility to better understand surgical procedures from a system point of view. This dissertation focuses on bridging the gap between these two lines of the research by developing computational models for task analysis in robotic-assisted surgery. The key step for advance study in robotic-assisted surgery and autonomous skill assessment is to develop techniques that are capable of recognizing fundamental surgical tasks intelligently. Surgical tasks and at a more granular level, surgical gestures, need to be quantified to make them amenable for further study. To answer to this query, we introduce a new framework, namely DTW-kNN, to recognize and classify three important surgical tasks including suturing, needle passing and knot tying based on kinematic data captured using da Vinci robotic surgery system. Our proposed method needs minimum preprocessing that results in simple, straightforward and accurate framework which can be applied for any autonomous control system. We also propose an unsupervised gesture segmentation and recognition (UGSR) method which has the ability to automatically segment and recognize temporal sequence of gestures in RMIS task. We also extent our model by applying soft boundary segmentation (Soft-UGSR) to address some of the challenges that exist in the surgical motion segmentation. The proposed algorithm can effectively model gradual transitions between surgical activities. Additionally, surgical training is undergoing a paradigm shift with more emphasis on the development of technical skills earlier in training. Thus metrics for the skills, especially objective metrics, become crucial. One field of surgery where such techniques can be developed is robotic surgery, as here all movements are already digitalized and therefore easily susceptible to analysis. Robotic surgery requires surgeons to perform a much longer and difficult training process which create numerous new challenges for surgical training. Hence, a new method of surgical skill assessment is required to ensure that surgeons have adequate skill level to be allowed to operate freely on patients. Among many possible approaches, those that provide noninvasive monitoring of expert surgeon and have the ability to automatically evaluate surgeon\u27s skill are of increased interest. Therefore, in this dissertation we develop a predictive framework for surgical skill assessment to automatically evaluate performance of surgeon in RMIS. Our classification framework is based on the Global Movement Features (GMFs) which extracted from kinematic movement data. The proposed method addresses some of the limitations in previous work and gives more insight about underlying patterns of surgical skill levels

Inferring Complex Activities for Context-aware Systems within Smart Environments

The rising ageing population worldwide and the prevalence of age-related conditions such as physical fragility, mental impairments and chronic diseases have significantly impacted the quality of life and caused a shortage of health and care services. Over-stretched healthcare providers are leading to a paradigm shift in public healthcare provisioning. Thus, Ambient Assisted Living (AAL) using Smart Homes (SH) technologies has been rigorously investigated to help address the aforementioned problems. Human Activity Recognition (HAR) is a critical component in AAL systems which enables applications such as just-in-time assistance, behaviour analysis, anomalies detection and emergency notifications. This thesis is aimed at investigating challenges faced in accurately recognising Activities of Daily Living (ADLs) performed by single or multiple inhabitants within smart environments. Specifically, this thesis explores five complementary research challenges in HAR. The first study contributes to knowledge by developing a semantic-enabled data segmentation approach with user-preferences. The second study takes the segmented set of sensor data to investigate and recognise human ADLs at multi-granular action level; coarse- and fine-grained action level. At the coarse-grained actions level, semantic relationships between the sensor, object and ADLs are deduced, whereas, at fine-grained action level, object usage at the satisfactory threshold with the evidence fused from multimodal sensor data is leveraged to verify the intended actions. Moreover, due to imprecise/vague interpretations of multimodal sensors and data fusion challenges, fuzzy set theory and fuzzy web ontology language (fuzzy-OWL) are leveraged. The third study focuses on incorporating uncertainties caused in HAR due to factors such as technological failure, object malfunction, and human errors. Hence, existing studies uncertainty theories and approaches are analysed and based on the findings, probabilistic ontology (PR-OWL) based HAR approach is proposed. The fourth study extends the first three studies to distinguish activities conducted by more than one inhabitant in a shared smart environment with the use of discriminative sensor-based techniques and time-series pattern analysis. The final study investigates in a suitable system architecture with a real-time smart environment tailored to AAL system and proposes microservices architecture with sensor-based off-the-shelf and bespoke sensing methods. The initial semantic-enabled data segmentation study was evaluated with 100% and 97.8% accuracy to segment sensor events under single and mixed activities scenarios. However, the average classification time taken to segment each sensor events have suffered from 3971ms and 62183ms for single and mixed activities scenarios, respectively. The second study to detect fine-grained-level user actions was evaluated with 30 and 153 fuzzy rules to detect two fine-grained movements with a pre-collected dataset from the real-time smart environment. The result of the second study indicate good average accuracy of 83.33% and 100% but with the high average duration of 24648ms and 105318ms, and posing further challenges for the scalability of fusion rule creations. The third study was evaluated by incorporating PR-OWL ontology with ADL ontologies and Semantic-Sensor-Network (SSN) ontology to define four types of uncertainties presented in the kitchen-based activity. The fourth study illustrated a case study to extended single-user AR to multi-user AR by combining RFID tags and fingerprint sensors discriminative sensors to identify and associate user actions with the aid of time-series analysis. The last study responds to the computations and performance requirements for the four studies by analysing and proposing microservices-based system architecture for AAL system. A future research investigation towards adopting fog/edge computing paradigms from cloud computing is discussed for higher availability, reduced network traffic/energy, cost, and creating a decentralised system. As a result of the five studies, this thesis develops a knowledge-driven framework to estimate and recognise multi-user activities at fine-grained level user actions. This framework integrates three complementary ontologies to conceptualise factual, fuzzy and uncertainties in the environment/ADLs, time-series analysis and discriminative sensing environment. Moreover, a distributed software architecture, multimodal sensor-based hardware prototypes, and other supportive utility tools such as simulator and synthetic ADL data generator for the experimentation were developed to support the evaluation of the proposed approaches. The distributed system is platform-independent and currently supported by an Android mobile application and web-browser based client interfaces for retrieving information such as live sensor events and HAR results

New Fundamental Technologies in Data Mining

The progress of data mining technology and large public popularity establish a need for a comprehensive text on the subject. The series of books entitled by "Data Mining" address the need by presenting in-depth description of novel mining algorithms and many useful applications. In addition to understanding each section deeply, the two books present useful hints and strategies to solving problems in the following chapters. The contributing authors have highlighted many future research directions that will foster multi-disciplinary collaborations and hence will lead to significant development in the field of data mining

Unsupervised Heterogeneous Domain Adaptation via Shared Fuzzy Equivalence Relations

© 1993-2012 IEEE. Unsupervised domain adaptation (UDA) aims to recognize newly emerged patterns in target domains, which may be unlabeled, by leveraging knowledge from patterns learnt from source domains. However, existing UDA models and algorithms still suffer from heterogeneous domains, known as the heterogeneous unsupervised domain adaptation (HeUDA) issue. To address this issue, this paper presents a novel HeUDA model via n-dimensional fuzzy geometry and fuzzy equivalence relations, called F-HeUDA. The n-dimensional fuzzy geometry is used to propose a metric to measure the similarity between features on one domain. Then, based on this metric, shared fuzzy equivalence relations (SFER) are proposed. The SFER can allow two domains to use the same α to get the same number of clustering categories. Through these clustering categories, knowledge from the heterogeneous source domain can be transferred to the unlabeled target domain. Different to existing HeUDA models, the proposed F-HeUDA model does not need that two domains must have the same number of instances. As a result, the proposed model has a better ability to handle the issue of small datasets. Experiments distributed across four real datasets were conducted to validate the proposed model. This testing regime demonstrates that the proposed model outperforms the state-of-The-Art models, especially when the target domain has very few instances

Bioinformatics

This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis. Each book section introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here