5,174 research outputs found
Autoencoders for strategic decision support
In the majority of executive domains, a notion of normality is involved in
most strategic decisions. However, few data-driven tools that support strategic
decision-making are available. We introduce and extend the use of autoencoders
to provide strategically relevant granular feedback. A first experiment
indicates that experts are inconsistent in their decision making, highlighting
the need for strategic decision support. Furthermore, using two large
industry-provided human resources datasets, the proposed solution is evaluated
in terms of ranking accuracy, synergy with human experts, and dimension-level
feedback. This three-point scheme is validated using (a) synthetic data, (b)
the perspective of data quality, (c) blind expert validation, and (d)
transparent expert evaluation. Our study confirms several principal weaknesses
of human decision-making and stresses the importance of synergy between a model
and humans. Moreover, unsupervised learning and in particular the autoencoder
are shown to be valuable tools for strategic decision-making
Quantification of volumetric morphometry and optical property in the cortex of human cerebellum at micrometer resolution
The surface of the human cerebellar cortex is much more tightly folded than the cerebral cortex. Volumetric analysis of cerebellar morphometry in magnetic resonance imaging studies suffers from insufficient resolution, and therefore has had limited impact on disease assessment. Automatic serial polarization-sensitive optical coherence tomography (as-PSOCT) is an emerging technique that offers the advantages of microscopic resolution and volumetric reconstruction of large-scale samples. In this study, we reconstructed multiple cubic centimeters of ex vivo human cerebellum tissue using as-PSOCT. The morphometric and optical properties of the cerebellar cortex across five subjects were quantified. While the molecular and granular layers exhibited similar mean thickness in the five subjects, the thickness varied greatly in the granular layer within subjects. Layer-specific optical property remained homogenous within individual subjects but showed higher cross-subject variability than layer thickness. High-resolution volumetric morphometry and optical property maps of human cerebellar cortex revealed by as-PSOCT have great potential to advance our understanding of cerebellar function and diseases
Topological Schemas of Memory Spaces
Hippocampal cognitive map---a neuronal representation of the spatial
environment---is broadly discussed in the computational neuroscience literature
for decades. More recent studies point out that hippocampus plays a major role
in producing yet another cognitive framework that incorporates not only
spatial, but also nonspatial memories---the memory space. However, unlike
cognitive maps, memory spaces have been barely studied from a theoretical
perspective. Here we propose an approach for modeling hippocampal memory spaces
as an epiphenomenon of neuronal spiking activity. First, we suggest that the
memory space may be viewed as a finite topological space---a hypothesis that
allows treating both spatial and nonspatial aspects of hippocampal function on
equal footing. We then model the topological properties of the memory space to
demonstrate that this concept naturally incorporates the notion of a cognitive
map. Lastly, we suggest a formal description of the memory consolidation
process and point out a connection between the proposed model of the memory
spaces to the so-called Morris' schemas, which emerge as the most compact
representation of the memory structure.Comment: 24 pages, 8 Figures, 1 Suppl. Figur
What is the functional role of adult neurogenesis in the hippocampus?
The dentate gyrus is part of the hippocampal memory system and special in
that it generates new neurons throughout life. Here we discuss the
question of what the functional role of these new neurons might be. Our
hypothesis is that they help the dentate gyrus to avoid the problem of
catastrophic interference when adapting to new environments. We assume
that old neurons are rather stable and preserve an optimal encoding
learned for known environments while new neurons are plastic to adapt to
those features that are qualitatively new in a new environment. A simple
network simulation demonstrates that adding new plastic neurons is indeed
a successful strategy for adaptation without catastrophic interference
A Theory of Granular Partitions
We have a variety of different ways of dividing up, classifying, mapping, sorting and listing the objects in reality. The theory of granular partitions presented here seeks to provide a general and unified basis for understanding such phenomena in formal terms that is more realistic than existing alternatives. Our theory has two orthogonal parts: the first is a theory of classification; it provides an account of partitions as cells and subcells; the second is a theory of reference or intentionality; it provides an account of how cells and subcells relate to objects in reality. We define a notion of well-formedness for partitions, and we give an account of what it means for a partition to project onto objects in reality. We continue by classifying partitions along three axes: (a) in terms of the degree of correspondence between partition cells and objects in reality; (b) in terms of the degree to which a partition represents the mereological structure of the domain it is projected onto; and (c) in terms of the degree of completeness with which a partition represents this domain
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