39,712 research outputs found

    Critical Point in Self-Organized Tissue Growth

    Full text link
    We present a theory of pattern formation in growing domains inspired by biological examples of tissue development. Gradients of signaling molecules regulate growth, while growth changes these graded chemical patterns by dilution and advection. We identify a critical point of this feedback dynamics, which is characterized by spatially homogeneous growth and proportional scaling of patterns with tissue length. We apply this theory to the biological model system of the developing wing of the fruit fly \textit{Drosophila melanogaster} and quantitatively identify signatures of the critical point.Comment: 5 pages, 3 figure

    Graded, Dynamically Routable Information Processing with Synfire-Gated Synfire Chains

    Full text link
    Coherent neural spiking and local field potentials are believed to be signatures of the binding and transfer of information in the brain. Coherent activity has now been measured experimentally in many regions of mammalian cortex. Synfire chains are one of the main theoretical constructs that have been appealed to to describe coherent spiking phenomena. However, for some time, it has been known that synchronous activity in feedforward networks asymptotically either approaches an attractor with fixed waveform and amplitude, or fails to propagate. This has limited their ability to explain graded neuronal responses. Recently, we have shown that pulse-gated synfire chains are capable of propagating graded information coded in mean population current or firing rate amplitudes. In particular, we showed that it is possible to use one synfire chain to provide gating pulses and a second, pulse-gated synfire chain to propagate graded information. We called these circuits synfire-gated synfire chains (SGSCs). Here, we present SGSCs in which graded information can rapidly cascade through a neural circuit, and show a correspondence between this type of transfer and a mean-field model in which gating pulses overlap in time. We show that SGSCs are robust in the presence of variability in population size, pulse timing and synaptic strength. Finally, we demonstrate the computational capabilities of SGSC-based information coding by implementing a self-contained, spike-based, modular neural circuit that is triggered by, then reads in streaming input, processes the input, then makes a decision based on the processed information and shuts itself down

    Graded Majorana spinors

    Full text link
    In many mathematical and physical contexts spinors are treated as Grassmann odd valued fields. We show that it is possible to extend the classification of reality conditions on such spinors by a new type of Majorana condition. In order to define this graded Majorana condition we make use of pseudo-conjugation, a rather unfamiliar extension of complex conjugation to supernumbers. Like the symplectic Majorana condition, the graded Majorana condition may be imposed, for example, in spacetimes in which the standard Majorana condition is inconsistent. However, in contrast to the symplectic condition, which requires duplicating the number of spinor fields, the graded condition can be imposed on a single Dirac spinor. We illustrate how graded Majorana spinors can be applied to supersymmetry by constructing a globally supersymmetric field theory in three-dimensional Euclidean space, an example of a spacetime where standard Majorana spinors do not exist.Comment: 16 pages, version to appear in J. Phys. A; AFK previously published under the name A. F. Schunc

    Hermitian forms for affine Hecke algebras

    Full text link
    We study star operations for Iwahori-Hecke algebras and invariant hermitian forms for finite dimensional modules over (graded) affine Hecke algebras with a view towards a unitarity algorithm.Comment: 29 pages, preliminary version. v2: the classification of star operations for the graded Hecke algebras and the construction of hermitian forms in the Iwahori case via Bernstein's projectives have been removed from this preprint and they will make the basis of a new pape
    corecore