Bootstrap Markov chain Monte Carlo and optimal solutions for the Law of Categorical Judgment (Corrected)

A novel procedure is described for accelerating the convergence of Markov chain Monte Carlo computations. The algorithm uses an adaptive bootstrap technique to generate candidate steps in the Markov Chain. It is efficient for symmetric, convex probability distributions, similar to multivariate Gaussians, and it can be used for Bayesian estimation or for obtaining maximum likelihood solutions with confidence limits. As a test case, the Law of Categorical Judgment (Corrected) was fitted with the algorithm to data sets from simulated rating scale experiments. The correct parameters were recovered from practical-sized data sets simulated for Full Signal Detection Theory and its special cases of standard Signal Detection Theory and Complementary Signal Detection Theory

Algorithmic Analysis Techniques for Molecular Imaging

This study addresses image processing techniques for two medical imaging modalities: Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI), which can be used in studies of human body functions and anatomy in a non-invasive manner. In PET, the so-called Partial Volume Effect (PVE) is caused by low spatial resolution of the modality. The efficiency of a set of PVE-correction methods is evaluated in the present study. These methods use information about tissue borders which have been acquired with the MRI technique. As another technique, a novel method is proposed for MRI brain image segmen- tation. A standard way of brain MRI is to use spatial prior information in image segmentation. While this works for adults and healthy neonates, the large variations in premature infants preclude its direct application. The proposed technique can be applied to both healthy and non-healthy premature infant brain MR images. Diffusion Weighted Imaging (DWI) is a MRI-based technique that can be used to create images for measuring physiological properties of cells on the structural level. We optimise the scanning parameters of DWI so that the required acquisition time can be reduced while still maintaining good image quality. In the present work, PVE correction methods, and physiological DWI models are evaluated in terms of repeatabilityof the results. This gives in- formation on the reliability of the measures given by the methods. The evaluations are done using physical phantom objects, correlation measure- ments against expert segmentations, computer simulations with realistic noise modelling, and with repeated measurements conducted on real pa- tients. In PET, the applicability and selection of a suitable partial volume correction method was found to depend on the target application. For MRI, the data-driven segmentation offers an alternative when using spatial prior is not feasible. For DWI, the distribution of b-values turns out to be a central factor affecting the time-quality ratio of the DWI acquisition. An optimal b-value distribution was determined. This helps to shorten the imaging time without hampering the diagnostic accuracy.Siirretty Doriast

Aberrant Effective Connectivity in Schizophrenia Patients during Appetitive Conditioning

It has recently been suggested that schizophrenia involves dysfunction in brain connectivity at a neural level, and a dysfunction in reward processing at a behavioral level. The purpose of the present study was to link these two levels of analyses by examining effective connectivity patterns between brain regions mediating reward learning in patients with schizophrenia and healthy, age-matched controls. To this aim, we used functional magnetic resonance imaging and galvanic skin recordings (GSR) while patients and controls performed an appetitive conditioning experiment with visual cues as the conditioned (CS) stimuli, and monetary reward as the appetitive unconditioned stimulus (US). Based on explicit stimulus contingency ratings, conditioning occurred in both groups; however, based on implicit, physiological GSR measures, patients failed to show differences between CS+ and CS− conditions. Healthy controls exhibited increased blood-oxygen-level dependent (BOLD) activity across striatal, hippocampal, and prefrontal regions and increased effective connectivity from the ventral striatum to the orbitofrontal cortex (OFC BA 11) in the CS+ compared to the CS− condition. Compared to controls, patients showed increased BOLD activity across a similar network of brain regions, and increased effective connectivity from the striatum to hippocampus and prefrontal regions in the CS− compared to the CS+ condition. The findings of increased BOLD activity and effective connectivity in response to the CS− in patients with schizophrenia offer insight into the aberrant assignment of motivational salience to non-reinforced stimuli during conditioning that is thought to accompany schizophrenia

A historical view on the maximum entropy

How to find unknown distributions is questioned in many pieces of research. There are several ways to figure them out, but the main question is which acts more reasonably than others. In this paper, we focus on the maximum entropy principle as a suitable method of discovering the unknown distribution, which recommends some prior information based on the available data set. We explain its features by reviewing some papers. Furthermore, we recommend some articles to study around the generalized maximum entropy issue, which is more suitable when autocorrelation data exists. Then, we list the beneficial features of the maximum entropy as a result. Finally, some disadvantages of entropy are expressed to have a complete look at the maximum entropy principle, and we list its drawbacks as the final step

Augmenting the Student-Teacher Feature Pyramid Matching Method for Better Unsupervised Anomaly Localization

Anomaly detection in images is the machine learning task of classifying inputs as normal or anomalous. Anomaly localization is the related task of segmenting input images into normal and anomalous regions. The output of an anomaly localization model is a 2D array, called an anomaly map, of pixel-level anomaly scores. For example, an anomaly localization model trained on images of non-defective industrial products should output high anomaly scores in image regions corresponding to visible defects. In unsupervised anomaly localization the model is trained solely on normal data, i.e. without labelled training observations that contain anomalies. This is often necessary as anomalous observations may be hard to obtain in sufficient quantities and labelling them is time-consuming and costly. Student-teacher feature pyramid matching (STFPM) is a recent and powerful method for unsupervised anomaly detection and localization that uses a pair of convolutional neural networks of identical architecture. In this thesis we propose two methods of augmenting STFPM to produce better segmentations. Our first method, discrepancy scaling, significantly improves the segmentation performance of STFPM by leveraging pre-calculated statistics containing information about the model’s behaviour on normal data. Our second method, student-teacher model assisted segmentation, uses a frozen STFPM model as a feature detector for a segmentation model which is then trained on data with artificially generated anomalies. Using this second method we are able to produce sharper anomaly maps for which it is easier to set a threshold value that produces good segmentations. Finally, we propose the concept of expected goodness of segmentation, a way of assessing the performance of unsupervised anomaly localization models that, in contrast to current metrics, explicitly takes into account the fact that a segmentation threshold needs to be set. Our primary method, discrepancy scaling, improves segmentation AUROC on the MVTec AD dataset over the base model by 13%, measured in the shrinkage of the residual (1.0 − AUROC). On the image-level anomaly detection task, a variant of the discrepancy scaling method improves performance by 12%

TEMPORAL CODING OF SPEECH IN HUMAN AUDITORY CORTEX

Human listeners can reliably recognize speech in complex listening environments. The underlying neural mechanisms, however, remain unclear and cannot yet be emulated by any artificial system. In this dissertation, we study how speech is represented in the human auditory cortex and how the neural representation contributes to reliable speech recognition. Cortical activity from normal hearing human subjects is noninvasively recorded using magnetoencephalography, during natural speech listening. It is first demonstrated that neural activity from auditory cortex is precisely synchronized to the slow temporal modulations of speech, when the speech signal is presented in a quiet listening environment. How this neural representation is affected by acoustic interference is then investigated. Acoustic interference degrades speech perception via two mechanisms, informational masking and energetic masking, which are addressed respectively by using a competing speech stream and a stationary noise as the interfering sound. When two speech streams are presented simultaneously, cortical activity is predominantly synchronized to the speech stream the listener attends to, even if the unattended, competing speech stream is 8 dB more intense. When speech is presented together with spectrally matched stationary noise, cortical activity remains precisely synchronized to the temporal modulations of speech until the noise is 9 dB more intense. Critically, the accuracy of neural synchronization to speech predicts how well individual listeners can understand speech in noise. Further analysis reveals that two neural sources contribute to speech synchronized cortical activity, one with a shorter response latency of about 50 ms and the other with a longer response latency of about 100 ms. The longer-latency component, but not the shorter-latency component, shows selectivity to the attended speech and invariance to background noise, indicating a transition from encoding the acoustic scene to encoding the behaviorally important auditory object, in auditory cortex. Taken together, we have demonstrated that during natural speech comprehension, neural activity in the human auditory cortex is precisely synchronized to the slow temporal modulations of speech. This neural synchronization is robust to acoustic interference, whether speech or noise, and therefore provides a strong candidate for the neural basis of acoustic background invariant speech recognition

Women in Artificial intelligence (AI)

This Special Issue, entitled "Women in Artificial Intelligence" includes 17 papers from leading women scientists. The papers cover a broad scope of research areas within Artificial Intelligence, including machine learning, perception, reasoning or planning, among others. The papers have applications to relevant fields, such as human health, finance, or education. It is worth noting that the Issue includes three papers that deal with different aspects of gender bias in Artificial Intelligence. All the papers have a woman as the first author. We can proudly say that these women are from countries worldwide, such as France, Czech Republic, United Kingdom, Australia, Bangladesh, Yemen, Romania, India, Cuba, Bangladesh and Spain. In conclusion, apart from its intrinsic scientific value as a Special Issue, combining interesting research works, this Special Issue intends to increase the invisibility of women in AI, showing where they are, what they do, and how they contribute to developments in Artificial Intelligence from their different places, positions, research branches and application fields. We planned to issue this book on the on Ada Lovelace Day (11/10/2022), a date internationally dedicated to the first computer programmer, a woman who had to fight the gender difficulties of her times, in the XIX century. We also thank the publisher for making this possible, thus allowing for this book to become a part of the international activities dedicated to celebrating the value of women in ICT all over the world. With this book, we want to pay homage to all the women that contributed over the years to the field of AI

Structural Disconnections Explain Brain Network Dysfunction after Stroke

Stroke causes focal brain lesions that disrupt functional connectivity (FC), a measure of activity synchronization, throughout distributed brain networks. It is often assumed that FC disruptions reflect damage to specific cortical regions. However, an alternative explanation is that they reflect the structural disconnection (SDC) of white matter pathways. Here, we compare these explanations using data from 114 stroke patients. Across multiple analyses, we find that SDC measures outperform focal damage measures, including damage to putative critical cortical regions, for explaining FC disruptions associated with stroke. We also identify a core mode of structure-function covariation that links the severity of interhemispheric SDCs to widespread FC disruptions across patients and that correlates with deficits in multiple behavioral domains. We conclude that a lesion\u27s impact on the structural connectome is what determines its impact on FC and that interhemispheric SDCs may play a particularly important role in mediating FC disruptions after stroke