13,409 research outputs found

    Quantum Mechanics Lecture Notes. Selected Chapters

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    These are extended lecture notes of the quantum mechanics course which I am teaching in the Weizmann Institute of Science graduate physics program. They cover the topics listed below. The first four chapter are posted here. Their content is detailed on the next page. The other chapters are planned to be added in the coming months. 1. Motion in External Electromagnetic Field. Gauge Fields in Quantum Mechanics. 2. Quantum Mechanics of Electromagnetic Field 3. Photon-Matter Interactions 4. Quantization of the Schr\"odinger Field (The Second Quantization) 5. Open Systems. Density Matrix 6. Adiabatic Theory. The Berry Phase. The Born-Oppenheimer Approximation 7. Mean Field Approaches for Many Body Systems -- Fermions and Boson

    Towards Reuse and Recycling of Lithium-ion Batteries: Tele-robotics for Disassembly of Electric Vehicle Batteries

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    Disassembly of electric vehicle batteries is a critical stage in recovery, recycling and re-use of high-value battery materials, but is complicated by limited standardisation, design complexity, compounded by uncertainty and safety issues from varying end-of-life condition. Telerobotics presents an avenue for semi-autonomous robotic disassembly that addresses these challenges. However, it is suggested that quality and realism of the user's haptic interactions with the environment is important for precise, contact-rich and safety-critical tasks. To investigate this proposition, we demonstrate the disassembly of a Nissan Leaf 2011 module stack as a basis for a comparative study between a traditional asymmetric haptic-'cobot' master-slave framework and identical master and slave cobots based on task completion time and success rate metrics. We demonstrate across a range of disassembly tasks a time reduction of 22%-57% is achieved using identical cobots, yet this improvement arises chiefly from an expanded workspace and 1:1 positional mapping, and suffers a 10-30% reduction in first attempt success rate. For unbolting and grasping, the realism of force feedback was comparatively less important than directional information encoded in the interaction, however, 1:1 force mapping strengthened environmental tactile cues for vacuum pick-and-place and contact cutting tasks.Comment: 21 pages, 12 figures, Submitted to Frontiers in Robotics and AI; Human-Robot Interactio

    Strategies for Early Learners

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    Welcome to learning about how to effectively plan curriculum for young children. This textbook will address: • Developing curriculum through the planning cycle • Theories that inform what we know about how children learn and the best ways for teachers to support learning • The three components of developmentally appropriate practice • Importance and value of play and intentional teaching • Different models of curriculum • Process of lesson planning (documenting planned experiences for children) • Physical, temporal, and social environments that set the stage for children’s learning • Appropriate guidance techniques to support children’s behaviors as the self-regulation abilities mature. • Planning for preschool-aged children in specific domains including o Physical development o Language and literacy o Math o Science o Creative (the visual and performing arts) o Diversity (social science and history) o Health and safety • Making children’s learning visible through documentation and assessmenthttps://scholar.utc.edu/open-textbooks/1001/thumbnail.jp

    The determinants of value addition: a crtitical analysis of global software engineering industry in Sri Lanka

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    It was evident through the literature that the perceived value delivery of the global software engineering industry is low due to various facts. Therefore, this research concerns global software product companies in Sri Lanka to explore the software engineering methods and practices in increasing the value addition. The overall aim of the study is to identify the key determinants for value addition in the global software engineering industry and critically evaluate the impact of them for the software product companies to help maximise the value addition to ultimately assure the sustainability of the industry. An exploratory research approach was used initially since findings would emerge while the study unfolds. Mixed method was employed as the literature itself was inadequate to investigate the problem effectively to formulate the research framework. Twenty-three face-to-face online interviews were conducted with the subject matter experts covering all the disciplines from the targeted organisations which was combined with the literature findings as well as the outcomes of the market research outcomes conducted by both government and nongovernment institutes. Data from the interviews were analysed using NVivo 12. The findings of the existing literature were verified through the exploratory study and the outcomes were used to formulate the questionnaire for the public survey. 371 responses were considered after cleansing the total responses received for the data analysis through SPSS 21 with alpha level 0.05. Internal consistency test was done before the descriptive analysis. After assuring the reliability of the dataset, the correlation test, multiple regression test and analysis of variance (ANOVA) test were carried out to fulfil the requirements of meeting the research objectives. Five determinants for value addition were identified along with the key themes for each area. They are staffing, delivery process, use of tools, governance, and technology infrastructure. The cross-functional and self-organised teams built around the value streams, employing a properly interconnected software delivery process with the right governance in the delivery pipelines, selection of tools and providing the right infrastructure increases the value delivery. Moreover, the constraints for value addition are poor interconnection in the internal processes, rigid functional hierarchies, inaccurate selections and uses of tools, inflexible team arrangements and inadequate focus for the technology infrastructure. The findings add to the existing body of knowledge on increasing the value addition by employing effective processes, practices and tools and the impacts of inaccurate applications the same in the global software engineering industry

    Exploring the Structure of Scattering Amplitudes in Quantum Field Theory: Scattering Equations, On-Shell Diagrams and Ambitwistor String Models in Gauge Theory and Gravity

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    In this thesis I analyse the structure of scattering amplitudes in super-symmetric gauge and gravitational theories in four dimensional spacetime, starting with a detailed review of background material accessible to a non-expert. I then analyse the 4D scattering equations, developing the theory of how they can be used to express scattering amplitudes at tree level. I go on to explain how the equations can be solved numerically using a Monte Carlo algorithm, and introduce my Mathematica package treeamps4dJAF which performs these calculations. Next I analyse the relation between the 4D scattering equations and on-shell diagrams in N = 4 super Yang-Mills, which provides a new perspective on the tree level amplitudes of the theory. I apply a similar analysis to N = 8 supergravity, developing the theory of on-shell diagrams to derive new Grassmannian integral formulae for the amplitudes of the theory. In both theories I derive a new worldsheet expression for the 4 point one loop amplitude supported on 4D scattering equations. Finally I use 4D ambitwistor string theory to analyse scattering amplitudes in N = 4 conformal supergravity, deriving new worldsheet formulae for both plane wave and non-plane wave amplitudes supported on 4D scattering equations. I introduce a new prescription to calculate the derivatives of on-shell variables with respect to momenta, and I use this to show that certain non-plane wave amplitudes can be calculated as momentum derivatives of amplitudes with plane wave states

    Networks: A study in Analysis and Design

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    In this dissertation, we will look at two fundamental aspects of Networks: Network Analysis and Network Design. In part A, we look at Network Analysis area of the dissertation which involves finding the densest subgraph in each graph. The densest subgraph extraction problem is fundamentally a non-linear optimization problem. Nevertheless, it can be solved in polynomial time by an exact algorithm based on the iterative solution of a series of max-flow sub-problems. To approach graphs with millions of vertices and edges, one must resort to heuristic algorithms. We provide an efficient implementation of a greedy heuristic from the literature that is extremely fast and has some nice theoretical properties. An extensive computational analysis shows that the proposed heuristic algorithm proved very effective on many test instances, often providing either the optimal solution or near-optimal solution within short computing times. In part-B, we discuss Network design, which is a cornerstone of mathematical optimization, is about defining the main characteristics of a network satisfying requirements on connectivity, capacity, and level-of-service. In multi-commodity network design, one is required to design a network minimizing the installation cost of its arcs and the operational cost to serve a set of point-to-point connections. This prototypical problem was recently enriched by additional constraints imposing that each origin-destination of a connection is served by a single path satisfying one or more level-of-service requirements, thus defining the Network Design with Service Requirements. These constraints are crucial, e.g., in telecommunications and computer networks, in order to ensure reliable and low-latency communication. We provide a new formulation for the problem, where variables are associated with paths satisfying the end-to-end service requirements. A fast algorithm for enumerating all the exponentially-many feasible paths and, when this is not viable, a column generation scheme that is embedded into a branch-and-cut-and-price algorithm is provided

    Development of in-vitro in-silico technologies for modelling and analysis of haematological malignancies

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    Worldwide, haematological malignancies are responsible for roughly 6% of all the cancer-related deaths. Leukaemias are one of the most severe types of cancer, as only about 40% of the patients have an overall survival of 10 years or more. Myelodysplastic Syndrome (MDS), a pre-leukaemic condition, is a blood disorder characterized by the presence of dysplastic, irregular, immature cells, or blasts, in the peripheral blood (PB) and in the bone marrow (BM), as well as multi-lineage cytopenias. We have created a detailed, lineage-specific, high-fidelity in-silico erythroid model that incorporates known biological stimuli (cytokines and hormones) and a competing diseased haematopoietic population, correctly capturing crucial biological checkpoints (EPO-dependent CFU-E differentiation) and replicating the in-vivo erythroid differentiation dynamics. In parallel, we have also proposed a long-term, cytokine-free 3D cell culture system for primary MDS cells, which was firstly optimized using easily-accessible healthy controls. This system enabled long-term (24-day) maintenance in culture with high (>75%) cell viability, promoting spontaneous expansion of erythroid phenotypes (CD71+/CD235a+) without the addition of any exogenous cytokines. Lastly, we have proposed a novel in-vitro in-silico framework using GC-MS metabolomics for the metabolic profiling of BM and PB plasma, aiming not only to discretize between haematological conditions but also to sub-classify MDS patients, potentially based on candidate biomarkers. Unsupervised multivariate statistical analysis showed clear intra- and inter-disease separation of samples of 5 distinct haematological malignancies, demonstrating the potential of this approach for disease characterization. The work herein presented paves the way for the development of in-vitro in-silico technologies to better, characterize, diagnose, model and target haematological malignancies such as MDS and AML.Open Acces

    Mapping Super-Relaxed States of Myosin Heads in Sarcomeres using Oblique Angle Fluorescent Microscopy

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    We have utilised modern methods of super-resolution fluorescent microscopy to spatially map fluorescently labelled ATP molecules in relaxed rabbit psoas skeletal muscles. For our imaging process, we have labelled ATP molecules with Rhodamine and Z-lines with Alexa488. Data from imaging these fluorophores have been collected using oblique angle fluorescent microscopy and further analysed to map super relaxed states (SRX) of myosin heads on the thick filament. Our experiments have concluded that most SRX of myosin heads were found in the C-zone of the thick filament, while other zones of thick filament had smaller populations of SRX. Further introduction of mavacamten (MAVA) to our imaging system has revealed an increase in SRX in both D and P zones, while the C zone population of SRX had remained constant. Further experiments must be conducted to establish a clear pattern and further proof our findings

    DataProVe: Fully Automated Conformance Verification Between Data Protection Policies and System Architectures

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    Privacy and data protection by design are relevant parts of the General Data Protection Regulation (GDPR), in which businesses and organisations are encouraged to implement measures at an early stage of the system design phase to fulfil data protection requirements. This paper addresses the policy and system architecture design and propose two variants of privacy policy language and architecture description language, respectively, for specifying and verifying data protection and privacy requirements. In addition, we develop a fully automated algorithm based on logic, for verifying three types of conformance relations (privacy, data protection, and functional conformance) between a policy and an architecture specified in our languages’ variants. Compared to related works, this approach supports a more systematic and fine-grained analysis of the privacy, data protection, and functional properties of a system. Our theoretical methods are then implemented as a software tool called DataProVe and its feasibility is demonstrated based on the centralised and decentralised approaches of COVID-19 contact tracing applications
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