Cancer growth and metastasis as a metaphor of Go gaming: An Ising model approach

© 2018 Barradas-Bautista et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestric ted use, distribution, and reproduction in any medium, provided the original author and source are credited. This work aims for modeling and simulating the metastasis of cancer, via the analogy between the cancer process and the board game Go. In the game of Go, black stones that play first could correspond to a metaphor of the birth, growth, and metastasis of cancer. Moreover, playing white stones on the second turn could correspond the inhibition of cancer invasion. Mathematical modeling and algorithmic simulation of Go may therefore benefit the efforts to deploy therapies to surpass cancer illness by providing insight into the cellular growth and expansion over a tissue area. We use the Ising Hamiltonian, that models the energy exchange in interacting particles, for modeling the cancer dynamics. Parameters in the energy function refer the biochemical elements that induce cancer birth, growth, and metastasis; as well as the biochemical immune system process of defense

Musical identities, learning and education: Some cross-cultural issues

In sum, the aims of this paper are to consider some of the ways in which individual musical identities are formed through formal and informal music-learning across a range of contexts afforded by the contemporary dialectical relations between local and global musical cultures; to suggest some ways in which both similarities and differences occur in the processes of musical identity-formation and the content of musical identities; and to consider some of the effects of globalisation and localisation in relation to the provision and content of formal music education. (DIPF/Orig.

Modeling two-language competition dynamics

During the last decade, much attention has been paid to language competition in the complex systems community, that is, how the fractions of speakers of several competing languages evolve in time. In this paper we review recent advances in this direction and focus on three aspects. First we consider the shift from two-state models to three state models that include the possibility of bilingual individuals. The understanding of the role played by bilingualism is essential in sociolinguistics. In particular, the question addressed is whether bilingualism facilitates the coexistence of languages. Second, we will analyze the effect of social interaction networks and physical barriers. Finally, we will show how to analyze the issue of bilingualism from a game theoretical perspective.Comment: 15 pages, 5 figures; published in the Special Issue of Advances in Complex Systems "Language Dynamics

Norm violation versus punishment risk in a social model of corruption

We analyze the onset of social-norm-violating behaviors when social punishment is present. To this aim, a compartmental model is introduced to illustrate the flows among the three possible states: Honest, corrupt, and ostracism. With this simple model we attempt to capture some essential ingredients such as the contagion of corrupt behaviors to honest agents, the delation of corrupt individuals by honest ones, and the warning to wrongdoers (fear like that triggers the conversion of corrupt people into honesty). In nonequilibrium statistical physics terms, the former dynamics can be viewed as a non-Hamiltonian kinetic spin-1 Ising model. After developing in full detail its mean-field theory and comparing its predictions with simulations made on regular networks, we derive the conditions for the emergence of corrupt behaviors and, more importantly, illustrate the key role of the warning-to-wrongdoers mechanism in the latter

2D growth processes: SLE and Loewner chains

This review provides an introduction to two dimensional growth processes. Although it covers a variety processes such as diffusion limited aggregation, it is mostly devoted to a detailed presentation of stochastic Schramm-Loewner evolutions (SLE) which are Markov processes describing interfaces in 2D critical systems. It starts with an informal discussion, using numerical simulations, of various examples of 2D growth processes and their connections with statistical mechanics. SLE is then introduced and Schramm's argument mapping conformally invariant interfaces to SLE is explained. A substantial part of the review is devoted to reveal the deep connections between statistical mechanics and processes, and more specifically to the present context, between 2D critical systems and SLE. Some of the SLE remarkable properties are explained, as well as the tools for computing with SLE. This review has been written with the aim of filling the gap between the mathematical and the physical literatures on the subject.Comment: A review on Stochastic Loewner evolutions for Physics Reports, 172 pages, low quality figures, better quality figures upon request to the authors, comments welcom