41,068 research outputs found

    Comparison of physical fitness between healthy and mild‚Äźto‚Äźmoderate asthmatic children with exercise symptoms: A cross‚Äźsectional study

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    .Objective Asthma is a chronic disease that may affect physical fitness, although its primary effects on exercise capacity, muscle strength, functionality and lifestyle, in children and adolescents, are still poorly understood. This study aimed to evaluate the differences in cardiorespiratory fitness, muscle strength, lifestyle, lung function, and functionality between asthmatics with exercise symptoms and healthy children. In addition, we have analyzed the association between clinical history and the presence of asthma. Study Design Cross-sectional study including 71 patients with a diagnosis of asthma and 71 healthy children and adolescents (7‚Äď17 years of age). Anthropometric data, clinical history, disease control, lifestyle (KIDMED and physical activity questionnaires), lung function (spirometry), exercise-induced bronchoconstriction test, aerobic fitness (cardiopulmonary exercise test), muscle strength and functionality (timed up and go; timed up and down stairs) were evaluated. Results Seventy-one patients with asthma (mean age 11.5‚ÄȬĪ‚ÄČ2.7) and 71 healthy subjects (mean age 10.7‚ÄȬĪ‚ÄČ2.5) were included. All asthmatic children had mild to moderate and stable asthma. EIB occurred in 56.3% of asthmatic children. Lung function was significantly (p‚ÄČ<‚ÄČ.05) lower in the asthmatic group when compared to healthy peers, as well as the cardiorespiratory fitness, muscle strength, lifestyle and functionality. Moreover, asthmatic children were more likely to have atopic dermatitis, allergic reactions, food allergies, and a family history of asthma when compared to healthy children. Conclusions Children with mild-to-moderate asthma presenting exercise symptoms show a reduction in cardiorespiratory fitness, muscle strength, lung function, functionality, and lifestyle when compared to healthy peers. The study provides data for pediatricians to support exercise practice aiming to improve prognosis and quality of life in asthmatic children.S

    Naturaleza estratégica de la responsabilidad social empresaria

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    p. 116-125Este art√≠culo eval√ļa la relaci√≥n entre la Estrategia Corporativa y la Responsabilidad Social Empresarial (RSE). M√°s espec√≠ficamente, en qu√© medida la RSE constituye un elemento integrante de la estrategia empresarial, tanto a nivel corporativo como de negocio. El mensaje es que la asunci√≥n de responsabilidad social tiene m√°s que ver con la consecuci√≥n de objetivos estrat√©gicos y al √©xito empresarial en el largo plazo que con el altruismo o cuestiones morales. Conocer la manera en que la RSE influye tanto a la estrategia corporativa como de negocio constituye el primer paso para realizar un dise√Īo adecuado de la estrategia mas conveniente para la empresa. Utilizando datos de la ciudadan√≠a espa√Īola, as√≠ como empresas operando en Espa√Īa demuestra los beneficios a largo plazo de incorporar la RSE en la estrategia corporativa.S

    How does firm ownership concentration and female directors influence tax haven foreign direct investment? Evidence from Asia-Pacific and OECD countries

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    The literature on tax havens utilization by multinational enterprises (MNEs) has largely focused on determinants that are financial or technological in nature. We contribute to this literature by showing important corporate governance determinants for tax haven utilization by Asia-Pacific and OECD country MNEs. Theoretically, we show that ownership concentration and female board membership influence tax haven utilization. Empirically, we show negative associations between ownership concentration and female board membership and the likelihood of owning a subsidiary in a tax haven. Based on our results, we draw a number of implications for theoretical and empirical work, which also opens the door for further investigation in this area

    Community engagement in Cutaneous Leishmaniasis research in Brazil, Ethiopia, and Sri Lanka: A decolonial approach for global health.

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    Cutaneous leishmaniasis (CL) is a parasitic skin disease endemic in at least 88 countries where it presents an urgent, albeit often "neglected" public health problem. In this paper, we discuss our model of decolonial community engagement in the ECLIPSE global health research program, which aims to improve physical and mental health outcomes for people with CL. The ECLIPSE program has four interlinked phases and underpinning each of these phases is sustained and robust community engagement and involvement that guides and informs all activities in ECLIPSE. Our decolonial approach implies that the model for community engagement will be different in Brazil, Ethiopia and Sri Lanka. Indeed, we adopt a critical anthropological approach to engaging with community members and it is precisely this approach we evaluate in this paper. The data and material we draw on were collected through qualitative research methods during community engagement activities. We established 13 Community Advisory Groups (CAGs): in Brazil ( = 4), Ethiopia ( = 6), and Sri Lanka ( = 3). We identified four overarching themes during a thematic analysis of the data set: (1) Establishing community advisory groups, (2) CAG membership and community representation, (3) Culturally appropriate and context-bespoke engagement, and (4) Relationships between researchers and community members. During our first period of ECLIPSE community engagement, we have debunked myths (for instance about communities being "disempowered"), critiqued our own practices (changing approaches in bringing together CAG members) and celebrated successes (notably fruitful online engagement during a challenging COVID-19 pandemic context). Our evaluation revealed a gap between the exemplary community engagement frameworks available in the literature and the messy, everyday reality of working in communities. In the ECLIPSE program, we have translated ideal(istic) principles espoused by such community engagement guidance into the practical realities of "doing engagement" in low-resourced communities. Our community engagement was underpinned by such ideal principles, but adapted to local sociocultural contexts, working within certain funding and regulatory constraints imposed on researchers. We conclude with a set of lessons learned and recommendations for the conduct of decolonial community engagement in global health research. [Abstract copyright: Copyright © 2022 Polidano, Parton, Agampodi, Agampodi, Haileselassie, Lalani, Mota, Price, Rodrigues, Tafere, Trad, Zerihun and Dikomitis.

    A life ‚Äėin and with nature?‚Äô Developing nature engaging and nature enhancing pedagogies for babies and toddlers

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    The holistic relationship between children and nature is at the heart of Froebel‚Äôs philosophy and practice: he took for granted that young children would grow up ‚Äėin‚Äô and ‚Äėwith‚Äô nature. This paper explores the contemporary relevance of this thinking to babies and toddlers in early childhood education and care (ECEC) settings. It is based on a research project funded by the Froebel Trust which explores outdoor provision in English settings. Our findings suggest that whilst the pedagogic potential of the outdoors for babies and toddlers appears to be generally recognised, there is little emphasis on supporting them to engage with the natural characteristics of the outdoor environment. Concerns about safety and an emphasis on physical activity mean that natural elements may be discouraged in favour of manufactured alternatives such as artificial grass or commercially produced resources. We argue that Froebelian philosophy offers a much-needed theoretical lens that can illuminate the limitations of such practices for both the human and non-human world. Importantly, we highlight the interconnectedness of human and environmental health and suggest the need to develop nature engaging and nature enhancing pedagogies from birth

    Study on the concordance between different SNP‚Äźgenotyping platforms in sheep

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    .Different SNP genotyping technologies are commonly used in multiple studies to perform QTL detection, genotype imputation, and genomic predictions. Therefore, genotyping errors cannot be ignored, as they can reduce the accuracy of different procedures applied in genomic selection, such as genomic imputation, genomic predictions, and false-positive results in genome-wide association studies. Currently, whole-genome resequencing (WGR) also offers the potential for variant calling analysis and high-throughput genotyping. WGR might overshadow array-based genotyping technologies due to the larger amount and precision of the genomic information provided; however, its comparatively higher price per individual still limits its use in larger populations. Thus, the objective of this work was to evaluate the accuracy of the two most popular SNP-chip technologies, namely, Affymetrix and Illumina, for high-throughput genotyping in sheep considering high-coverage WGR datasets as references. Analyses were performed using two reference sheep genome assemblies, the popular Oar_v3.1 reference genome and the latest available version Oar_rambouillet_v1.0. Our results demonstrate that the genotypes from both platforms are suggested to have high concordance rates with the genotypes determined from reference WGR datasets (96.59% and 99.51% for Affymetrix and Illumina technologies, respectively). The concordance results provided in the current study can pinpoint low reproducible markers across multiple platforms used for sheep genotyping data. Comparing results using two reference genome assemblies also informs how genome assembly quality can influence genotype concordance rates among different genotyping platforms. Moreover, we describe an efficient pipeline to test the reliability of markers included in sheep SNP-chip panels against WGR datasets available on public databases. This pipeline may be helpful for discarding low-reliability markers before exploiting genomic information for gene mapping analyses or genomic predictionS

    Gamification in E-Learning: game factors to strengthen specific English pronunciation features in undergraduate students at UPTC Sogamoso

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    Appendix A Characterization survey (104), Appendix B. EFL Students‚Äô questionnaire (109), Appendix C. Characterization survey: data treatment question (113), Appendix D. Informed consent letter, English version (114), Appendix E. Carta de consentimiento informado, versi√≥n en espa√Īol (117), Appendix F. Time Schedule (120), Appendix G. Sample Challenges at Moodle (126), Appendix H. Participants‚Äô questionnaire results (128).La gamificaci√≥n es un t√©rmino que suele denotar el uso de componentes del juego en situaciones no relacionadas con el juego en s√≠ para crear experiencias de aprendizaje agradables, divertidas y motivadoras para los estudiantes (Werbach y Hunter, 2012). Por lo tanto, el an√°lisis de los factores b√°sicos de los juegos se convierte en algo esencial a la hora de definir y utilizar la gamificaci√≥n como estrategia de mediaci√≥n del ingl√©s como lengua extranjera para fortalecer rasgos espec√≠ficos de pronunciaci√≥n en los estudiantes de pregrado de la UPTC Sogamoso. El procedimiento de estudio se basa en la investigaci√≥n acci√≥n mediante la implementaci√≥n de la estrategia de gamificaci√≥n para la mediaci√≥n en la pronunciaci√≥n del ingl√©s, orientada a treinta estudiantes de diferentes programas de ingenier√≠a, administraci√≥n y tecnolog√≠a con niveles heterog√©neos de dominio del ingl√©s. Las actividades se centran principalmente en la producci√≥n de sonidos, el ritmo, el acento y la entonaci√≥n, los rasgos de pronunciaci√≥n segmental y suprasegmental. Los resultados arrojaron una evidente mejora en las caracter√≠sticas segm√©ntales y suprasegmentales de la percepci√≥n en la pronunciaci√≥n de los participantes as√≠ como la contribuci√≥n del objetivo de los juegos a la instrucci√≥n fon√©tica y fonol√≥gica, la sensaci√≥n en el juego a la motivaci√≥n para mejorar la pronunciaci√≥n, el reto establecido en los juegos a la actitud positiva de los participantes, y la sociabilidad a la exposici√≥n practica de la pronunciaci√≥n inglesa.Gamification is a relatively new term that often denotes the use of game components in situations unrelated to the game itself to create enjoyable, fun, and motivating learning experiences for students (Werbach and Hunter, 2012). Therefore, analyzing the games' basic factors becomes essential when defining and using gamification as a strategy for English as Foreign Language mediation to strengthen specific pronunciation features in UPTC Sogamoso undergraduate students. The study procedure is based on action research by implementing the gamification strategy for mediation in English pronunciation, oriented to thirty students from different engineering, management, and technology programs at heterogeneous levels of English proficiency. The activities mainly focus on sound production, rhythm, stress, and intonation, segmental and suprasegmental pronunciation features. The results showed an evident improvement in the segmental and suprasegmental features of the participants' pronunciation perception as well as the contribution of game goals to phonetics and phonological instruction, the game sensation to the motivation for pronunciation improvement, the game challenge to the participants' positive attitude, and the sociality to the English pronunciation exposure practice
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