904 research outputs found
A direct comparison of high-speed methods for the numerical Abel transform
The Abel transform is a mathematical operation that transforms a
cylindrically symmetric three-dimensional (3D) object into its two-dimensional
(2D) projection. The inverse Abel transform reconstructs the 3D object from the
2D projection. Abel transforms have wide application across numerous fields of
science, especially chemical physics, astronomy, and the study of laser-plasma
plumes. Consequently, many numerical methods for the Abel transform have been
developed, which makes it challenging to select the ideal method for a specific
application. In this work eight transform methods have been incorporated into a
single, open-source Python software package (PyAbel) to provide a direct
comparison of the capabilities, advantages, and relative computational
efficiency of each transform method. Most of the tested methods provide
similar, high-quality results. However, the computational efficiency varies
across several orders of magnitude. By optimizing the algorithms, we find that
some transform methods are sufficiently fast to transform 1-megapixel images at
more than 100 frames per second on a desktop personal computer. In addition, we
demonstrate the transform of gigapixel images.Comment: 9 pages, 5 figure
Scale Stain: Multi-Resolution Feature Enhancement in Pathology Visualization
Digital whole-slide images of pathological tissue samples have recently
become feasible for use within routine diagnostic practice. These gigapixel
sized images enable pathologists to perform reviews using computer workstations
instead of microscopes. Existing workstations visualize scanned images by
providing a zoomable image space that reproduces the capabilities of the
microscope. This paper presents a novel visualization approach that enables
filtering of the scale-space according to color preference. The visualization
method reveals diagnostically important patterns that are otherwise not
visible. The paper demonstrates how this approach has been implemented into a
fully functional prototype that lets the user navigate the visualization
parameter space in real time. The prototype was evaluated for two common
clinical tasks with eight pathologists in a within-subjects study. The data
reveal that task efficiency increased by 15% using the prototype, with
maintained accuracy. By analyzing behavioral strategies, it was possible to
conclude that efficiency gain was caused by a reduction of the panning needed
to perform systematic search of the images. The prototype system was well
received by the pathologists who did not detect any risks that would hinder use
in clinical routine
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