3D Motion Estimation By Evidence Gathering

In this paper we introduce an algorithm for 3D motion estimation in point clouds that is based on Chasles’ kinematic theorem. The proposed algorithm estimates 3D motion parameters directly from the data by exploiting the geometry of rigid transformation using an evidence gathering technique in a Hough-voting-like approach. The algorithm provides an alternative to the feature description and matching pipelines commonly used by numerous 3D object recognition and registration algorithms, as it does not involve keypoint detection and feature descriptor computation and matching. To the best of our knowledge, this is the first research to use kinematics theorems in an evidence gathering framework for motion estimation and surface matching without the use of any given correspondences. Moreover, we propose a method for voting for 3D motion parameters using a one-dimensional accumulator space, which enables voting for motion parameters more efficiently than other methods that use up to 7-dimensional accumulator spaces

Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates

The study of cerebral anatomy in developing neonates is of great importance for the understanding of brain development during the early period of life. This dissertation therefore focuses on three challenges in the modelling of cerebral anatomy in neonates during brain development. The methods that have been developed all use Magnetic Resonance Images (MRI) as source data. To facilitate study of vascular development in the neonatal period, a set of image analysis algorithms are developed to automatically extract and model cerebral vessel trees. The whole process consists of cerebral vessel tracking from automatically placed seed points, vessel tree generation, and vasculature registration and matching. These algorithms have been tested on clinical Time-of- Flight (TOF) MR angiographic datasets. To facilitate study of the neonatal cortex a complete cerebral cortex segmentation and reconstruction pipeline has been developed. Segmentation of the neonatal cortex is not effectively done by existing algorithms designed for the adult brain because the contrast between grey and white matter is reversed. This causes pixels containing tissue mixtures to be incorrectly labelled by conventional methods. The neonatal cortical segmentation method that has been developed is based on a novel expectation-maximization (EM) method with explicit correction for mislabelled partial volume voxels. Based on the resulting cortical segmentation, an implicit surface evolution technique is adopted for the reconstruction of the cortex in neonates. The performance of the method is investigated by performing a detailed landmark study. To facilitate study of cortical development, a cortical surface registration algorithm for aligning the cortical surface is developed. The method first inflates extracted cortical surfaces and then performs a non-rigid surface registration using free-form deformations (FFDs) to remove residual alignment. Validation experiments using data labelled by an expert observer demonstrate that the method can capture local changes and follow the growth of specific sulcus

Shape localization, quantification and correspondence using Region Matching Algorithm

We propose a method for local, region-based matching of planar shapes, especially as those shapes that change over time. This is a problem fundamental to medical imaging, specifically the comparison over time of mammograms. The method is based on the non-emergence and non-enhancement of maxima, as well as the causality principle of integral invariant scale space. The core idea of our Region Matching Algorithm (RMA) is to divide a shape into a number of “salient” regions and then to compare all such regions for local similarity in order to quantitatively identify new growths or partial/complete occlusions. The algorithm has several advantages over commonly used methods for shape comparison of segmented regions. First, it provides improved key-point alignment for optimal shape correspondence. Second, it identifies localized changes such as new growths as well as complete/partial occlusion in corresponding regions by dividing the segmented region into sub-regions based upon the extrema that persist over a sufficient range of scales. Third, the algorithm does not depend upon the spatial locations of mammographic features and eliminates the need for registration to identify salient changes over time. Finally, the algorithm is fast to compute and requires no human intervention. We apply the method to temporal pairs of mammograms in order to detect potentially important differences between them