480 research outputs found

    Aerospace medicine and biology. A continuing bibliography with indexes, supplement 195

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    This bibliography lists 148 reports, articles, and other documents introduced into the NASA scientific and technical information system in June 1979

    Computer modeling and signal analysis of cardiovascular physiology

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    This dissertation aims to study cardiovascular physiology from the cellular level to the whole heart level to the body level using numerical approaches. A mathematical model was developed to describe electromechanical interaction in the heart. The model integrates cardio-electrophysiology and cardiac mechanics through excitation-induced contraction and deformation-induced currents. A finite element based parallel simulation scheme was developed to investigate coupled electrical and mechanical functions. The developed model and numerical scheme were utilized to study cardiovascular dynamics at cellular, tissue and organ levels. The influence of ion channel blockade on cardiac alternans was investigated. It was found that the channel blocker may significantly change the critical pacing period corresponding to the onset of alternans as well as the alternans’ amplitude. The influence of electro-mechanical coupling on cardiac alternans was also investigated. The study supported the earlier assumptions that discordant alternans is induced by the interaction of conduction velocity and action potential duration restitution at high pacing rates. However, mechanical contraction may influence the spatial pattern and onset of discordant alternans. Computer algorithms were developed for analysis of human physiology. The 12-lead electrocardiography (ECG) is the gold standard for diagnosis of various cardiac abnormalities. However, disturbances and mistakes may modify physiological waves in ECG and lead to wrong diagnoses. This dissertation developed advanced signal analysis techniques and computer software to detect and suppress artifacts and errors in ECG. These algorithms can help to improve the quality of health care when integrated into medical devices or services. Moreover, computer algorithms were developed to predict patient mortality in intensive care units using various physiological measures. Models and analysis techniques developed here may help to improve the quality of health care

    Topics in Adaptive Optics

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    Advances in adaptive optics technology and applications move forward at a rapid pace. The basic idea of wavefront compensation in real-time has been around since the mid 1970s. The first widely used application of adaptive optics was for compensating atmospheric turbulence effects in astronomical imaging and laser beam propagation. While some topics have been researched and reported for years, even decades, new applications and advances in the supporting technologies occur almost daily. This book brings together 11 original chapters related to adaptive optics, written by an international group of invited authors. Topics include atmospheric turbulence characterization, astronomy with large telescopes, image post-processing, high power laser distortion compensation, adaptive optics and the human eye, wavefront sensors, and deformable mirrors

    Treatise on Hearing: The Temporal Auditory Imaging Theory Inspired by Optics and Communication

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    A new theory of mammalian hearing is presented, which accounts for the auditory image in the midbrain (inferior colliculus) of objects in the acoustical environment of the listener. It is shown that the ear is a temporal imaging system that comprises three transformations of the envelope functions: cochlear group-delay dispersion, cochlear time lensing, and neural group-delay dispersion. These elements are analogous to the optical transformations in vision of diffraction between the object and the eye, spatial lensing by the lens, and second diffraction between the lens and the retina. Unlike the eye, it is established that the human auditory system is naturally defocused, so that coherent stimuli do not react to the defocus, whereas completely incoherent stimuli are impacted by it and may be blurred by design. It is argued that the auditory system can use this differential focusing to enhance or degrade the images of real-world acoustical objects that are partially coherent. The theory is founded on coherence and temporal imaging theories that were adopted from optics. In addition to the imaging transformations, the corresponding inverse-domain modulation transfer functions are derived and interpreted with consideration to the nonuniform neural sampling operation of the auditory nerve. These ideas are used to rigorously initiate the concepts of sharpness and blur in auditory imaging, auditory aberrations, and auditory depth of field. In parallel, ideas from communication theory are used to show that the organ of Corti functions as a multichannel phase-locked loop (PLL) that constitutes the point of entry for auditory phase locking and hence conserves the signal coherence. It provides an anchor for a dual coherent and noncoherent auditory detection in the auditory brain that culminates in auditory accommodation. Implications on hearing impairments are discussed as well.Comment: 603 pages, 131 figures, 13 tables, 1570 reference

    The Characterization Of The Infrasonic Noise Field And Its Effects On Least Squares Estimation

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    Thesis (Ph.D.) University of Alaska Fairbanks, 2007Localization of the source of an acoustic wave propagating through the atmosphere is not a new problem. Location methods date back to World War I, when sound location was used to determine enemy artillery positions. Since the drafting of the Comprehensive Nuclear-Test-Ban Treaty in 1996 there has been increased interest in the accurate location of distant sources using infrasound. A standard method of acoustic source location is triangulation of the source from multi-array back azimuth estimates. For waves traveling long distances through the atmosphere, the most appropriate method of estimating the back azimuth is the least squares estimate (LSE). Under the assumption of an acoustic signal corrupted with additive Gaussian, white, uncorrelated noise the LSE is theoretically the minimum variance, unbiased estimate of the slowness vector. The infrasonic noise field present at most arrays is known to violate the assumption of white, uncorrelated noise. The following work characterizes the noise field at two infrasound arrays operated by the University of Alaska Fairbanks, The power distribution and coherence of the noise fields was determined from atmospheric pressure measurements collected from 2003-2006. The estimated power distribution and coherence of the noise field were not the white, uncorrelated noise field assumed in the analytic derivation of the LSE of the slowness vector. The performance of the LSE of azimuth and trace velocity with the empirically derived noise field was numerically compared to its performance under the standard noise assumptions. The effect of violating the correlation assumption was also investigated. The inclusion of clutter in the noise field introduced a dependence to the performance of the LSE on the relative signal amplitude. If the signal-to-clutter ratio was above 10 dB, the parameter estimates made with the correlated noise field were comparable to the estimates made with uncorrelated noise. From the results of these numerical studies, it was determined that the assumption of Gaussian, white, uncorrelated noise had little effect on the performance of the LSE at signal-to-noise ratios greater than 10 dB, but tended to over estimate the performance of the LSE at lower signal-to-noise ratios

    Geodetic Sciences

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    Space geodetic techniques, e.g., global navigation satellite systems (GNSS), Very Long Baseline Interferometry (VLBI), satellite gravimetry and altimetry, and GNSS Reflectometry & Radio Occultation, are capable of measuring small changes of the Earth�s shape, rotation, and gravity field, as well as mass changes in the Earth system with an unprecedented accuracy. This book is devoted to presenting recent results and development in space geodetic techniques and sciences, including GNSS, VLBI, gravimetry, geoid, geodetic atmosphere, geodetic geophysics and geodetic mass transport associated with the ocean, hydrology, cryosphere and solid-Earth. This book provides a good reference for geodetic techniques, engineers, scientists as well as user community

    Objekt-Manipulation und Steuerung der Greifkraft durch Verwendung von Taktilen Sensoren

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    This dissertation describes a new type of tactile sensor and an improved version of the dynamic tactile sensing approach that can provide a regularly updated and accurate estimate of minimum applied forces for use in the control of gripper manipulation. The pre-slip sensing algorithm is proposed and implemented into two-finger robot gripper. An algorithm that can discriminate between types of contact surface and recognize objects at the contact stage is also proposed. A technique for recognizing objects using tactile sensor arrays, and a method based on the quadric surface parameter for classifying grasped objects is described. Tactile arrays can recognize surface types on contact, making it possible for a tactile system to recognize translation, rotation, and scaling of an object independently.Diese Dissertation beschreibt eine neue Art von taktilen Sensoren und einen verbesserten Ansatz zur dynamischen Erfassung von taktilen daten, der in regelmäßigen Zeitabständen eine genaue Bewertung der minimalen Greifkraft liefert, die zur Steuerung des Greifers nötig ist. Ein Berechnungsverfahren zur Voraussage des Schlupfs, das in einen Zwei-Finger-Greifarm eines Roboters eingebaut wurde, wird vorgestellt. Auch ein Algorithmus zur Unterscheidung von verschiedenen Oberflächenarten und zur Erkennung von Objektformen bei der Berührung wird vorgestellt. Ein Verfahren zur Objekterkennung mit Hilfe einer Matrix aus taktilen Sensoren und eine Methode zur Klassifikation ergriffener Objekte, basierend auf den Daten einer rechteckigen Oberfläche, werden beschrieben. Mit Hilfe dieser Matrix können unter schiedliche Arten von Oberflächen bei Berührung erkannt werden, was es für das Tastsystem möglich macht, Verschiebung, Drehung und Größe eines Objektes unabhängig voneinander zu erkennen

    The perceptual flow of phonetic feature processing

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