1,817 research outputs found
Adaptive fuzzy clustering in constructing parametric images for low SNR functional imaging
Author name used in this publication: Michael FulhamAuthor name used in this publication: Dagan FengRefereed conference paper2008-2009 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe
Event-Based Motion Segmentation by Motion Compensation
In contrast to traditional cameras, whose pixels have a common exposure time,
event-based cameras are novel bio-inspired sensors whose pixels work
independently and asynchronously output intensity changes (called "events"),
with microsecond resolution. Since events are caused by the apparent motion of
objects, event-based cameras sample visual information based on the scene
dynamics and are, therefore, a more natural fit than traditional cameras to
acquire motion, especially at high speeds, where traditional cameras suffer
from motion blur. However, distinguishing between events caused by different
moving objects and by the camera's ego-motion is a challenging task. We present
the first per-event segmentation method for splitting a scene into
independently moving objects. Our method jointly estimates the event-object
associations (i.e., segmentation) and the motion parameters of the objects (or
the background) by maximization of an objective function, which builds upon
recent results on event-based motion-compensation. We provide a thorough
evaluation of our method on a public dataset, outperforming the
state-of-the-art by as much as 10%. We also show the first quantitative
evaluation of a segmentation algorithm for event cameras, yielding around 90%
accuracy at 4 pixels relative displacement.Comment: When viewed in Acrobat Reader, several of the figures animate. Video:
https://youtu.be/0q6ap_OSBA
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State of the Art of Level Set Methods in Segmentation and Registration of Medical Imaging Modalities
Segmentation of medical images is an important step in various applications such as visualization, quantitative analysis and image-guided surgery. Numerous segmentation methods have been developed in the past two decades for extraction of organ contours on medical images. Low-level segmentation methods, such as pixel-based clustering, region growing, and filter-based edge detection, require additional pre-processing and post-processing as well as considerable amounts of expert intervention or information of the objects of interest. Furthermore the subsequent analysis of segmented objects is hampered by the primitive, pixel or voxel level representations from those region-based segmentation. Deformable models, on the other hand, provide an explicit representation of the boundary and the shape of the object. They combine several desirable features such as inherent connectivity and smoothness, which counteract noise and boundary irregularities, as well as the ability to incorporate knowledge about the object of interest. However, parametric deformable models have two main limitations. First, in situations where the initial model and desired object boundary differ greatly in size and shape, the model must be re-parameterized dynamically to faithfully recover the object boundary. The second limitation is that it has difficulty dealing with topological adaptation such as splitting or merging model parts, a useful property for recovering either multiple objects or objects with unknown topology. This difficulty is caused by the fact that a new parameterization must be constructed whenever topology change occurs, which requires sophisticated schemes. Level set deformable models, also referred to as geometric deformable models, provide an elegant solution to address the primary limitations of parametric deformable models. These methods have drawn a great deal of attention since their introduction in 1988. Advantages of the contour implicit formulation of the deformable model over parametric formulation include: (1) no parameterization of the contour, (2) topological flexibility, (3) good numerical stability, (4) straightforward extension of the 2D formulation to n-D. Recent reviews on the subject include papers from Suri. In this chapter we give a general overview of the level set segmentation methods with emphasize on new frameworks recently introduced in the context of medical imaging problems. We then introduce novel approaches that aim at combining segmentation and registration in a level set formulation. Finally we review a selective set of clinical works with detailed validation of the level set methods for several clinical applications
PET-guided delineation of radiation therapy treatment volumes: a survey of image segmentation techniques
Historically, anatomical CT and MR images were used to delineate the gross tumour volumes (GTVs) for radiotherapy treatment planning. The capabilities offered by modern radiation therapy units and the widespread availability of combined PET/CT scanners stimulated the development of biological PET imaging-guided radiation therapy treatment planning with the aim to produce highly conformal radiation dose distribution to the tumour. One of the most difficult issues facing PET-based treatment planning is the accurate delineation of target regions from typical blurred and noisy functional images. The major problems encountered are image segmentation and imperfect system response function. Image segmentation is defined as the process of classifying the voxels of an image into a set of distinct classes. The difficulty in PET image segmentation is compounded by the low spatial resolution and high noise characteristics of PET images. Despite the difficulties and known limitations, several image segmentation approaches have been proposed and used in the clinical setting including thresholding, edge detection, region growing, clustering, stochastic models, deformable models, classifiers and several other approaches. A detailed description of the various approaches proposed in the literature is reviewed. Moreover, we also briefly discuss some important considerations and limitations of the widely used techniques to guide practitioners in the field of radiation oncology. The strategies followed for validation and comparative assessment of various PET segmentation approaches are described. Future opportunities and the current challenges facing the adoption of PET-guided delineation of target volumes and its role in basic and clinical research are also addresse
Fully automated 3D segmentation of dopamine transporter SPECT images using an estimation-based approach
Quantitative measures of uptake in caudate, putamen, and globus pallidus in
dopamine transporter (DaT) brain SPECT have potential as biomarkers for the
severity of Parkinson disease. Reliable quantification of uptake requires
accurate segmentation of these regions. However, segmentation is challenging in
DaT SPECT due to partial-volume effects, system noise, physiological
variability, and the small size of these regions. To address these challenges,
we propose an estimation-based approach to segmentation. This approach
estimates the posterior mean of the fractional volume occupied by caudate,
putamen, and globus pallidus within each voxel of a 3D SPECT image. The
estimate is obtained by minimizing a cost function based on the binary
cross-entropy loss between the true and estimated fractional volumes over a
population of SPECT images, where the distribution of the true fractional
volumes is obtained from magnetic resonance images from clinical populations.
The proposed method accounts for both the sources of partial-volume effects in
SPECT, namely the limited system resolution and tissue-fraction effects. The
method was implemented using an encoder-decoder network and evaluated using
realistic clinically guided SPECT simulation studies, where the ground-truth
fractional volumes were known. The method significantly outperformed all other
considered segmentation methods and yielded accurate segmentation with dice
similarity coefficients of ~ 0.80 for all regions. The method was relatively
insensitive to changes in voxel size. Further, the method was relatively robust
up to +/- 10 degrees of patient head tilt along transaxial, sagittal, and
coronal planes. Overall, the results demonstrate the efficacy of the proposed
method to yield accurate fully automated segmentation of caudate, putamen, and
globus pallidus in 3D DaT-SPECT images
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