Soft computing applied to optimization, computer vision and medicine

Artificial intelligence has permeated almost every area of life in modern society, and its significance continues to grow. As a result, in recent years, Soft Computing has emerged as a powerful set of methodologies that propose innovative and robust solutions to a variety of complex problems. Soft Computing methods, because of their broad range of application, have the potential to significantly improve human living conditions. The motivation for the present research emerged from this background and possibility. This research aims to accomplish two main objectives: On the one hand, it endeavors to bridge the gap between Soft Computing techniques and their application to intricate problems. On the other hand, it explores the hypothetical benefits of Soft Computing methodologies as novel effective tools for such problems. This thesis synthesizes the results of extensive research on Soft Computing methods and their applications to optimization, Computer Vision, and medicine. This work is composed of several individual projects, which employ classical and new optimization algorithms. The manuscript presented here intends to provide an overview of the different aspects of Soft Computing methods in order to enable the reader to reach a global understanding of the field. Therefore, this document is assembled as a monograph that summarizes the outcomes of these projects across 12 chapters. The chapters are structured so that they can be read independently. The key focus of this work is the application and design of Soft Computing approaches for solving problems in the following: Block Matching, Pattern Detection, Thresholding, Corner Detection, Template Matching, Circle Detection, Color Segmentation, Leukocyte Detection, and Breast Thermogram Analysis. One of the outcomes presented in this thesis involves the development of two evolutionary approaches for global optimization. These were tested over complex benchmark datasets and showed promising results, thus opening the debate for future applications. Moreover, the applications for Computer Vision and medicine presented in this work have highlighted the utility of different Soft Computing methodologies in the solution of problems in such subjects. A milestone in this area is the translation of the Computer Vision and medical issues into optimization problems. Additionally, this work also strives to provide tools for combating public health issues by expanding the concepts to automated detection and diagnosis aid for pathologies such as Leukemia and breast cancer. The application of Soft Computing techniques in this field has attracted great interest worldwide due to the exponential growth of these diseases. Lastly, the use of Fuzzy Logic, Artificial Neural Networks, and Expert Systems in many everyday domestic appliances, such as washing machines, cookers, and refrigerators is now a reality. Many other industrial and commercial applications of Soft Computing have also been integrated into everyday use, and this is expected to increase within the next decade. Therefore, the research conducted here contributes an important piece for expanding these developments. The applications presented in this work are intended to serve as technological tools that can then be used in the development of new devices

Fuzzy Logic

Fuzzy Logic is becoming an essential method of solving problems in all domains. It gives tremendous impact on the design of autonomous intelligent systems. The purpose of this book is to introduce Hybrid Algorithms, Techniques, and Implementations of Fuzzy Logic. The book consists of thirteen chapters highlighting models and principles of fuzzy logic and issues on its techniques and implementations. The intended readers of this book are engineers, researchers, and graduate students interested in fuzzy logic systems

Computer Architecture in Industrial, Biomechanical and Biomedical Engineering

This book aims to provide state-of-the-art information on computer architecture and simulation in industry, engineering, and clinical scenarios. Accepted submissions are high in scientific value and provide a significant contribution to computer architecture. Each submission expands upon novel and innovative research where the methods, analysis, and conclusions are robust and of the highest standard. This book is a valuable resource for researchers, students, non-governmental organizations, and key decision-makers involved in earthquake disaster management systems at the national, regional, and local levels

CAD system for lung nodule analysis.

Lung cancer is the deadliest type of known cancer in the United States, claiming hundreds of thousands of lives each year. However, despite the high mortality rate, the 5-year survival rate after resection of Stage 1A non–small cell lung cancer is currently in the range of 62%– 82% and in recent studies even 90%. Patient survival is highly correlated with early detection. Computed Tomography (CT) technology services the early detection of lung cancer tremendously by offering a minimally invasive medical diagnostic tool. Some early types of lung cancer begin with a small mass of tissue within the lung, less than 3 cm in diameter, called a nodule. Most nodules found in a lung are benign, but a small population of them becomes malignant over time. Expert analysis of CT scans is the first step in determining whether a nodule presents a possibility for malignancy but, due to such low spatial support, many potentially harmful nodules go undetected until other symptoms motivate a more thorough search. Computer Vision and Pattern Recognition techniques can play a significant role in aiding the process of detecting and diagnosing lung nodules. This thesis outlines the development of a CAD system which, given an input CT scan, provides a functional and fast, second-opinion diagnosis to physicians. The entire process of lung nodule screening has been cast as a system, which can be enhanced by modern computing technology, with the hopes of providing a feasible diagnostic tool for clinical use. It should be noted that the proposed CAD system is presented as a tool for experts—not a replacement for them. The primary motivation of this thesis is the design of a system that could act as a catalyst for reducing the mortality rate associated with lung cancer

Advancements and Breakthroughs in Ultrasound Imaging

Ultrasonic imaging is a powerful diagnostic tool available to medical practitioners, engineers and researchers today. Due to the relative safety, and the non-invasive nature, ultrasonic imaging has become one of the most rapidly advancing technologies. These rapid advances are directly related to the parallel advancements in electronics, computing, and transducer technology together with sophisticated signal processing techniques. This book focuses on state of the art developments in ultrasonic imaging applications and underlying technologies presented by leading practitioners and researchers from many parts of the world

Image synthesis based on a model of human vision

Modern computer graphics systems are able to construct renderings of such high quality that viewers are deceived into regarding the images as coming from a photographic source. Large amounts of computing resources are expended in this rendering process, using complex mathematical models of lighting and shading. However, psychophysical experiments have revealed that viewers only regard certain informative regions within a presented image. Furthermore, it has been shown that these visually important regions contain low-level visual feature differences that attract the attention of the viewer. This thesis will present a new approach to image synthesis that exploits these experimental findings by modulating the spatial quality of image regions by their visual importance. Efficiency gains are therefore reaped, without sacrificing much of the perceived quality of the image. Two tasks must be undertaken to achieve this goal. Firstly, the design of an appropriate region-based model of visual importance, and secondly, the modification of progressive rendering techniques to effect an importance-based rendering approach. A rule-based fuzzy logic model is presented that computes, using spatial feature differences, the relative visual importance of regions in an image. This model improves upon previous work by incorporating threshold effects induced by global feature difference distributions and by using texture concentration measures. A modified approach to progressive ray-tracing is also presented. This new approach uses the visual importance model to guide the progressive refinement of an image. In addition, this concept of visual importance has been incorporated into supersampling, texture mapping and computer animation techniques. Experimental results are presented, illustrating the efficiency gains reaped from using this method of progressive rendering. This visual importance-based rendering approach is expected to have applications in the entertainment industry, where image fidelity may be sacrificed for efficiency purposes, as long as the overall visual impression of the scene is maintained. Different aspects of the approach should find many other applications in image compression, image retrieval, progressive data transmission and active robotic vision

Image similarity in medical images

Recent experiments have indicated a strong influence of the substrate grain orientation on the self-ordering in anodic porous alumina. Anodic porous alumina with straight pore channels grown in a stable, self-ordered manner is formed on (001) oriented Al grain, while disordered porous pattern is formed on (101) oriented Al grain with tilted pore channels growing in an unstable manner. In this work, numerical simulation of the pore growth process is carried out to understand this phenomenon. The rate-determining step of the oxide growth is assumed to be the Cabrera-Mott barrier at the oxide/electrolyte (o/e) interface, while the substrate is assumed to determine the ratio β between the ionization and oxidation reactions at the metal/oxide (m/o) interface. By numerically solving the electric field inside a growing porous alumina during anodization, the migration rates of the ions and hence the evolution of the o/e and m/o interfaces are computed. The simulated results show that pore growth is more stable when β is higher. A higher β corresponds to more Al ionized and migrating away from the m/o interface rather than being oxidized, and hence a higher retained O:Al ratio in the oxide. Experimentally measured oxygen content in the self-ordered porous alumina on (001) Al is indeed found to be about 3% higher than that in the disordered alumina on (101) Al, in agreement with the theoretical prediction. The results, therefore, suggest that ionization on (001) Al substrate is relatively easier than on (101) Al, and this leads to the more stable growth of the pore channels on (001) Al

A robust framework for medical image segmentation through adaptable class-specific representation

Medical image segmentation is an increasingly important component in virtual pathology, diagnostic imaging and computer-assisted surgery. Better hardware for image acquisition and a variety of advanced visualisation methods have paved the way for the development of computer based tools for medical image analysis and interpretation. The routine use of medical imaging scans of multiple modalities has been growing over the last decades and data sets such as the Visible Human Project have introduced a new modality in the form of colour cryo section data. These developments have given rise to an increasing need for better automatic and semiautomatic segmentation methods. The work presented in this thesis concerns the development of a new framework for robust semi-automatic segmentation of medical imaging data of multiple modalities. Following the specification of a set of conceptual and technical requirements, the framework known as ACSR (Adaptable Class-Specific Representation) is developed in the first case for 2D colour cryo section segmentation. This is achieved through the development of a novel algorithm for adaptable class-specific sampling of point neighbourhoods, known as the PGA (Path Growing Algorithm), combined with Learning Vector Quantization. The framework is extended to accommodate 3D volume segmentation of cryo section data and subsequently segmentation of single and multi-channel greyscale MRl data. For the latter the issues of inhomogeneity and noise are specifically addressed. Evaluation is based on comparison with previously published results on standard simulated and real data sets, using visual presentation, ground truth comparison and human observer experiments. ACSR provides the user with a simple and intuitive visual initialisation process followed by a fully automatic segmentation. Results on both cryo section and MRI data compare favourably to existing methods, demonstrating robustness both to common artefacts and multiple user initialisations. Further developments into specific clinical applications are discussed in the future work section