4,487 research outputs found
Intima-Media Thickness: Setting a Standard for a Completely Automated Method of Ultrasound Measurement
The intima - media thickness (IMT) of the common carotid artery is a widely used clinical marker of severe cardiovascular diseases. IMT is usually manually measured on longitudinal B-Mode ultrasound images. Many computer-based techniques for IMT measurement have been proposed to overcome the limits of manual segmentation. Most of these, however, require a certain degree of user interaction. In this paper we describe a new completely automated layers extraction (CALEXia) technique for the segmentation and IMT measurement of carotid wall in ultrasound images. CALEXia is based on an integrated approach consisting of feature extraction, line fitting, and classification that enables the automated tracing of the carotid adventitial walls. IMT is then measured by relying on a fuzzy K-means classifier. We tested CALEXia on a database of 200 images. We compared CALEXia performances to those of a previously developed methodology that was based on signal analysis (CULEXsa). Three trained operators manually segmented the images and the average profiles were considered as the ground truth. The average error from CALEXia for lumen - intima (LI) and media - adventitia (MA) interface tracings were 1.46 ± 1.51 pixel (0.091 ± 0.093 mm) and 0.40 ± 0.87 pixel (0.025 ± 0.055 mm), respectively. The corresponding errors for CULEXsa were 0.55 ± 0.51 pixels (0.035 ± 0.032 mm) and 0.59 ± 0.46 pixels (0.037 ± 0.029 mm). The IMT measurement error was equal to 0.87 ± 0.56 pixel (0.054 ± 0.035 mm) for CALEXia and 0.12 ± 0.14 pixel (0.01 ± 0.01 mm) for CULEXsa. Thus, CALEXia showed limited performance in segmenting the LI interface, but outperformed CULEXsa in the MA interface and in the number of images correctly processed (10 for CALEXia and 16 for CULEXsa). Based on two complementary strategies, we anticipate fusing them for further IMT improvement
Self-Configuring and Evolving Fuzzy Image Thresholding
Every segmentation algorithm has parameters that need to be adjusted in order
to achieve good results. Evolving fuzzy systems for adjustment of segmentation
parameters have been proposed recently (Evolving fuzzy image segmentation --
EFIS [1]. However, similar to any other algorithm, EFIS too suffers from a few
limitations when used in practice. As a major drawback, EFIS depends on
detection of the object of interest for feature calculation, a task that is
highly application-dependent. In this paper, a new version of EFIS is proposed
to overcome these limitations. The new EFIS, called self-configuring EFIS
(SC-EFIS), uses available training data to auto-configure the parameters that
are fixed in EFIS. As well, the proposed SC-EFIS relies on a feature selection
process that does not require the detection of a region of interest (ROI).Comment: To appear in proceedings of The 14th International Conference on
Machine Learning and Applications (IEEE ICMLA 2015), Miami, Florida, USA,
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Segmentation of ultrasound images of thyroid nodule for assisting fine needle aspiration cytology
The incidence of thyroid nodule is very high and generally increases with the
age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid
nodule can be completely cured if detected early. Fine needle aspiration
cytology is a recognized early diagnosis method of thyroid nodule. There are
still some limitations in the fine needle aspiration cytology, and the
ultrasound diagnosis of thyroid nodule has become the first choice for
auxiliary examination of thyroid nodular disease. If we could combine medical
imaging technology and fine needle aspiration cytology, the diagnostic rate of
thyroid nodule would be improved significantly. The properties of ultrasound
will degrade the image quality, which makes it difficult to recognize the edges
for physicians. Image segmentation technique based on graph theory has become a
research hotspot at present. Normalized cut (Ncut) is a representative one,
which is suitable for segmentation of feature parts of medical image. However,
how to solve the normalized cut has become a problem, which needs large memory
capacity and heavy calculation of weight matrix. It always generates over
segmentation or less segmentation which leads to inaccurate in the
segmentation. The speckle noise in B ultrasound image of thyroid tumor makes
the quality of the image deteriorate. In the light of this characteristic, we
combine the anisotropic diffusion model with the normalized cut in this paper.
After the enhancement of anisotropic diffusion model, it removes the noise in
the B ultrasound image while preserves the important edges and local details.
This reduces the amount of computation in constructing the weight matrix of the
improved normalized cut and improves the accuracy of the final segmentation
results. The feasibility of the method is proved by the experimental results.Comment: 15pages,13figure
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