3,107 research outputs found
The use of multilayer network analysis in animal behaviour
Network analysis has driven key developments in research on animal behaviour
by providing quantitative methods to study the social structures of animal
groups and populations. A recent formalism, known as \emph{multilayer network
analysis}, has advanced the study of multifaceted networked systems in many
disciplines. It offers novel ways to study and quantify animal behaviour as
connected 'layers' of interactions. In this article, we review common questions
in animal behaviour that can be studied using a multilayer approach, and we
link these questions to specific analyses. We outline the types of behavioural
data and questions that may be suitable to study using multilayer network
analysis. We detail several multilayer methods, which can provide new insights
into questions about animal sociality at individual, group, population, and
evolutionary levels of organisation. We give examples for how to implement
multilayer methods to demonstrate how taking a multilayer approach can alter
inferences about social structure and the positions of individuals within such
a structure. Finally, we discuss caveats to undertaking multilayer network
analysis in the study of animal social networks, and we call attention to
methodological challenges for the application of these approaches. Our aim is
to instigate the study of new questions about animal sociality using the new
toolbox of multilayer network analysis.Comment: Thoroughly revised; title changed slightl
Community Detection and Improved Detectability in Multiplex Networks
We investigate the widely encountered problem of detecting communities in
multiplex networks, such as social networks, with an unknown arbitrary
heterogeneous structure. To improve detectability, we propose a generative
model that leverages the multiplicity of a single community in multiple layers,
with no prior assumption on the relation of communities among different layers.
Our model relies on a novel idea of incorporating a large set of generic
localized community label constraints across the layers, in conjunction with
the celebrated Stochastic Block Model (SBM) in each layer. Accordingly, we
build a probabilistic graphical model over the entire multiplex network by
treating the constraints as Bayesian priors. We mathematically prove that these
constraints/priors promote existence of identical communities across layers
without introducing further correlation between individual communities. The
constraints are further tailored to render a sparse graphical model and the
numerically efficient Belief Propagation algorithm is subsequently employed. We
further demonstrate by numerical experiments that in the presence of consistent
communities between different layers, consistent communities are matched, and
the detectability is improved over a single layer. We compare our model with a
"correlated model" which exploits the prior knowledge of community correlation
between layers. Similar detectability improvement is obtained under such a
correlation, even though our model relies on much milder assumptions than the
correlated model. Our model even shows a better detection performance over a
certain correlation and signal to noise ratio (SNR) range. In the absence of
community correlation, the correlation model naturally fails, while ours
maintains its performance
Multilayer Networks
In most natural and engineered systems, a set of entities interact with each
other in complicated patterns that can encompass multiple types of
relationships, change in time, and include other types of complications. Such
systems include multiple subsystems and layers of connectivity, and it is
important to take such "multilayer" features into account to try to improve our
understanding of complex systems. Consequently, it is necessary to generalize
"traditional" network theory by developing (and validating) a framework and
associated tools to study multilayer systems in a comprehensive fashion. The
origins of such efforts date back several decades and arose in multiple
disciplines, and now the study of multilayer networks has become one of the
most important directions in network science. In this paper, we discuss the
history of multilayer networks (and related concepts) and review the exploding
body of work on such networks. To unify the disparate terminology in the large
body of recent work, we discuss a general framework for multilayer networks,
construct a dictionary of terminology to relate the numerous existing concepts
to each other, and provide a thorough discussion that compares, contrasts, and
translates between related notions such as multilayer networks, multiplex
networks, interdependent networks, networks of networks, and many others. We
also survey and discuss existing data sets that can be represented as
multilayer networks. We review attempts to generalize single-layer-network
diagnostics to multilayer networks. We also discuss the rapidly expanding
research on multilayer-network models and notions like community structure,
connected components, tensor decompositions, and various types of dynamical
processes on multilayer networks. We conclude with a summary and an outlook.Comment: Working paper; 59 pages, 8 figure
The use of multilayer network analysis in animal behaviour
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.We gratefully acknowledge the 806 supporters of MX16: the UC Davis Institute for Social Sciences, the U.S. Army Research Office 807 under Multidisciplinary University Research Initiative Award No. W911NF-13-1-0340, the UC 808 Davis Complexity Sciences Center, the UC Davis Anthropology Department, the UC Davis 809 Graduate Student Association, the UC Davis Department of Engineering, and the UC Davis 810 Office of Research.Network analysis has driven key developments in research on animal behaviour by providing quantitative methods to study the social structures of animal groups and populations. A recent formalism, known as multilayer network analysis, has advanced the study of multifaceted networked systems in many disciplines. It offers novel ways to study and quantify animal behaviour through connected ‘layers’ of interactions. In this article, we review common questions in animal behaviour that can be studied using a multilayer approach, and we link these questions to specific analyses. We outline the types of behavioural data and questions that may be suitable to study using multilayer network analysis. We detail several multilayer methods, which can provide new insights into questions about animal sociality at individual, group, population and evolutionary levels of organization. We give examples for how to implement multilayer methods to demonstrate how taking a multilayer approach can alter inferences about social structure and the positions of individuals within such a structure. Finally, we discuss caveats to undertaking multilayer network analysis in the study of animal social networks, and we call attention to methodological challenges for the application of these approaches. Our aim is to instigate the study of new questions about animal sociality using the new toolbox of multilayer network analysis.Natural Environment Research Council (NERC)National Science Foundation (NSF) Graduate Research FellowshipNFS IOS grantNIH R01NERC standard gran
Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study
<p>Abstract</p> <p>Background</p> <p>Proteins that interact in vivo tend to reside within the same or "adjacent" subcellular compartments. This observation provides opportunities to reveal protein subcellular localization in the context of the protein-protein interaction (PPI) network. However, so far, only a few efforts based on heuristic rules have been made in this regard.</p> <p>Results</p> <p>We systematically and quantitatively validate the hypothesis that proteins physically interacting with each other probably share at least one common subcellular localization. With the result, for the first time, four graph-based semi-supervised learning algorithms, Majority, <it>χ</it><sup>2</sup>-score, GenMultiCut and FunFlow originally proposed for protein function prediction, are introduced to assign "multiplex localization" to proteins. We analyze these approaches by performing a large-scale cross validation on a <it>Saccharomyces cerevisiae </it>proteome compiled from BioGRID and comparing their predictions for 22 protein subcellular localizations. Furthermore, we build an ensemble classifier to associate 529 unlabeled and 137 ambiguously-annotated proteins with subcellular localizations, most of which have been verified in the previous experimental studies.</p> <p>Conclusions</p> <p>Physical interaction of proteins has actually provided an essential clue for their co-localization. Compared to the local approaches, the global algorithms consistently achieve a superior performance.</p
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