1,497 research outputs found
Hierarchical Multi-resolution Mesh Networks for Brain Decoding
We propose a new framework, called Hierarchical Multi-resolution Mesh
Networks (HMMNs), which establishes a set of brain networks at multiple time
resolutions of fMRI signal to represent the underlying cognitive process. The
suggested framework, first, decomposes the fMRI signal into various frequency
subbands using wavelet transforms. Then, a brain network, called mesh network,
is formed at each subband by ensembling a set of local meshes. The locality
around each anatomic region is defined with respect to a neighborhood system
based on functional connectivity. The arc weights of a mesh are estimated by
ridge regression formed among the average region time series. In the final
step, the adjacency matrices of mesh networks obtained at different subbands
are ensembled for brain decoding under a hierarchical learning architecture,
called, fuzzy stacked generalization (FSG). Our results on Human Connectome
Project task-fMRI dataset reflect that the suggested HMMN model can
successfully discriminate tasks by extracting complementary information
obtained from mesh arc weights of multiple subbands. We study the topological
properties of the mesh networks at different resolutions using the network
measures, namely, node degree, node strength, betweenness centrality and global
efficiency; and investigate the connectivity of anatomic regions, during a
cognitive task. We observe significant variations among the network topologies
obtained for different subbands. We, also, analyze the diversity properties of
classifier ensemble, trained by the mesh networks in multiple subbands and
observe that the classifiers in the ensemble collaborate with each other to
fuse the complementary information freed at each subband. We conclude that the
fMRI data, recorded during a cognitive task, embed diverse information across
the anatomic regions at each resolution.Comment: 18 page
Abusive Language Detection in Online Conversations by Combining Content-and Graph-based Features
In recent years, online social networks have allowed worldwide users to meet
and discuss. As guarantors of these communities, the administrators of these
platforms must prevent users from adopting inappropriate behaviors. This
verification task, mainly done by humans, is more and more difficult due to the
ever growing amount of messages to check. Methods have been proposed to
automatize this moderation process, mainly by providing approaches based on the
textual content of the exchanged messages. Recent work has also shown that
characteristics derived from the structure of conversations, in the form of
conversational graphs, can help detecting these abusive messages. In this
paper, we propose to take advantage of both sources of information by proposing
fusion methods integrating content-and graph-based features. Our experiments on
raw chat logs show that the content of the messages, but also of their dynamics
within a conversation contain partially complementary information, allowing
performance improvements on an abusive message classification task with a final
F-measure of 93.26%
SALSA: A Novel Dataset for Multimodal Group Behavior Analysis
Studying free-standing conversational groups (FCGs) in unstructured social
settings (e.g., cocktail party ) is gratifying due to the wealth of information
available at the group (mining social networks) and individual (recognizing
native behavioral and personality traits) levels. However, analyzing social
scenes involving FCGs is also highly challenging due to the difficulty in
extracting behavioral cues such as target locations, their speaking activity
and head/body pose due to crowdedness and presence of extreme occlusions. To
this end, we propose SALSA, a novel dataset facilitating multimodal and
Synergetic sociAL Scene Analysis, and make two main contributions to research
on automated social interaction analysis: (1) SALSA records social interactions
among 18 participants in a natural, indoor environment for over 60 minutes,
under the poster presentation and cocktail party contexts presenting
difficulties in the form of low-resolution images, lighting variations,
numerous occlusions, reverberations and interfering sound sources; (2) To
alleviate these problems we facilitate multimodal analysis by recording the
social interplay using four static surveillance cameras and sociometric badges
worn by each participant, comprising the microphone, accelerometer, bluetooth
and infrared sensors. In addition to raw data, we also provide annotations
concerning individuals' personality as well as their position, head, body
orientation and F-formation information over the entire event duration. Through
extensive experiments with state-of-the-art approaches, we show (a) the
limitations of current methods and (b) how the recorded multiple cues
synergetically aid automatic analysis of social interactions. SALSA is
available at http://tev.fbk.eu/salsa.Comment: 14 pages, 11 figure
Evaluating 35 Methods to Generate Structural Connectomes Using Pairwise Classification
There is no consensus on how to construct structural brain networks from
diffusion MRI. How variations in pre-processing steps affect network
reliability and its ability to distinguish subjects remains opaque. In this
work, we address this issue by comparing 35 structural connectome-building
pipelines. We vary diffusion reconstruction models, tractography algorithms and
parcellations. Next, we classify structural connectome pairs as either
belonging to the same individual or not. Connectome weights and eight
topological derivative measures form our feature set. For experiments, we use
three test-retest datasets from the Consortium for Reliability and
Reproducibility (CoRR) comprised of a total of 105 individuals. We also compare
pairwise classification results to a commonly used parametric test-retest
measure, Intraclass Correlation Coefficient (ICC).Comment: Accepted for MICCAI 2017, 8 pages, 3 figure
Characterizing disease states from topological properties of transcriptional regulatory networks
BACKGROUND: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. Here we present new paradigms of data Separation based on construction of transcriptional regulatory networks for normal and abnormal cells using sequence predictions, literature based data and gene expression studies. We analyzed expression datasets from a number of diseased and normal cells, including different types of acute leukemia, and breast cancer with variable clinical outcome. RESULTS: We constructed sample-specific regulatory networks to identify links between transcription factors (TFs) and regulated genes that differentiate between healthy and diseased states. This approach carries the advantage of identifying key transcription factor-gene pairs with differential activity between healthy and diseased states rather than merely using gene expression profiles, thus alluding to processes that may be involved in gene deregulation. We then generalized this approach by studying simultaneous changes in functionality of multiple regulatory links pointing to a regulated gene or emanating from one TF (or changes in gene centrality defined by its in-degree or out-degree measures, respectively). We found that samples can often be separated based on these measures of gene centrality more robustly than using individual links. We examined distributions of distances (the number of links needed to traverse the path between each pair of genes) in the transcriptional networks for gene subsets whose collective expression profiles could best separate each dataset into predefined groups. We found that genes that optimally classify samples are concentrated in neighborhoods in the gene regulatory networks. This suggests that genes that are deregulated in diseased states exhibit a remarkable degree of connectivity. CONCLUSION: Transcription factor-regulated gene links and centrality of genes on transcriptional networks can be used to differentiate between cell types. Transcriptional network blueprints can be used as a basis for further research into gene deregulation in diseased states
Laplacian Mixture Modeling for Network Analysis and Unsupervised Learning on Graphs
Laplacian mixture models identify overlapping regions of influence in
unlabeled graph and network data in a scalable and computationally efficient
way, yielding useful low-dimensional representations. By combining Laplacian
eigenspace and finite mixture modeling methods, they provide probabilistic or
fuzzy dimensionality reductions or domain decompositions for a variety of input
data types, including mixture distributions, feature vectors, and graphs or
networks. Provable optimal recovery using the algorithm is analytically shown
for a nontrivial class of cluster graphs. Heuristic approximations for scalable
high-performance implementations are described and empirically tested.
Connections to PageRank and community detection in network analysis demonstrate
the wide applicability of this approach. The origins of fuzzy spectral methods,
beginning with generalized heat or diffusion equations in physics, are reviewed
and summarized. Comparisons to other dimensionality reduction and clustering
methods for challenging unsupervised machine learning problems are also
discussed.Comment: 13 figures, 35 reference
Learning to Rank Academic Experts in the DBLP Dataset
Expert finding is an information retrieval task that is concerned with the
search for the most knowledgeable people with respect to a specific topic, and
the search is based on documents that describe people's activities. The task
involves taking a user query as input and returning a list of people who are
sorted by their level of expertise with respect to the user query. Despite
recent interest in the area, the current state-of-the-art techniques lack in
principled approaches for optimally combining different sources of evidence.
This article proposes two frameworks for combining multiple estimators of
expertise. These estimators are derived from textual contents, from
graph-structure of the citation patterns for the community of experts, and from
profile information about the experts. More specifically, this article explores
the use of supervised learning to rank methods, as well as rank aggregation
approaches, for combing all of the estimators of expertise. Several supervised
learning algorithms, which are representative of the pointwise, pairwise and
listwise approaches, were tested, and various state-of-the-art data fusion
techniques were also explored for the rank aggregation framework. Experiments
that were performed on a dataset of academic publications from the Computer
Science domain attest the adequacy of the proposed approaches.Comment: Expert Systems, 2013. arXiv admin note: text overlap with
arXiv:1302.041
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