Efficient mining of discriminative molecular fragments

Frequent pattern discovery in structured data is receiving an increasing attention in many application areas of sciences. However, the computational complexity and the large amount of data to be explored often make the sequential algorithms unsuitable. In this context high performance distributed computing becomes a very interesting and promising approach. In this paper we present a parallel formulation of the frequent subgraph mining problem to discover interesting patterns in molecular compounds. The application is characterized by a highly irregular tree-structured computation. No estimation is available for task workloads, which show a power-law distribution in a wide range. The proposed approach allows dynamic resource aggregation and provides fault and latency tolerance. These features make the distributed application suitable for multi-domain heterogeneous environments, such as computational Grids. The distributed application has been evaluated on the well known National Cancer Institute’s HIV-screening dataset

Efficient chain structure for high-utility sequential pattern mining

High-utility sequential pattern mining (HUSPM) is an emerging topic in data mining, which considers both utility and sequence factors to derive the set of high-utility sequential patterns (HUSPs) from the quantitative databases. Several works have been presented to reduce the computational cost by variants of pruning strategies. In this paper, we present an efficient sequence-utility (SU)-chain structure, which can be used to store more relevant information to improve mining performance. Based on the SU-Chain structure, the existing pruning strategies can also be utilized here to early prune the unpromising candidates and obtain the satisfied HUSPs. Experiments are then compared with the state-of-the-art HUSPM algorithms and the results showed that the SU-Chain-based model can efficiently improve the efficiency performance than the existing HUSPM algorithms in terms of runtime and number of the determined candidates