1,032 research outputs found
Semantic Context Forests for Learning-Based Knee Cartilage Segmentation in 3D MR Images
The automatic segmentation of human knee cartilage from 3D MR images is a
useful yet challenging task due to the thin sheet structure of the cartilage
with diffuse boundaries and inhomogeneous intensities. In this paper, we
present an iterative multi-class learning method to segment the femoral, tibial
and patellar cartilage simultaneously, which effectively exploits the spatial
contextual constraints between bone and cartilage, and also between different
cartilages. First, based on the fact that the cartilage grows in only certain
area of the corresponding bone surface, we extract the distance features of not
only to the surface of the bone, but more informatively, to the densely
registered anatomical landmarks on the bone surface. Second, we introduce a set
of iterative discriminative classifiers that at each iteration, probability
comparison features are constructed from the class confidence maps derived by
previously learned classifiers. These features automatically embed the semantic
context information between different cartilages of interest. Validated on a
total of 176 volumes from the Osteoarthritis Initiative (OAI) dataset, the
proposed approach demonstrates high robustness and accuracy of segmentation in
comparison with existing state-of-the-art MR cartilage segmentation methods.Comment: MICCAI 2013: Workshop on Medical Computer Visio
FACTS: Fully Automatic CT Segmentation of a Hip Joint
Extraction of surface models of a hip joint from CT data is a pre-requisite step for computer assisted diagnosis and planning (CADP) of periacetabular osteotomy (PAO). Most of existing CADP systems are based on manual segmentation, which is time-consuming and hard to achieve reproducible results. In this paper, we present a Fully Automatic CT Segmentation (FACTS) approach to simultaneously extract both pelvic and femoral models. Our approach works by combining fast random forest (RF) regression based landmark detection, multi-atlas based segmentation, with articulated statistical shape model (aSSM) based fitting. The two fundamental contributions of our approach are: (1) an improved fast Gaussian transform (IFGT) is used within the RF regression framework for a fast and accurate landmark detection, which then allows for a fully automatic initialization of the multi-atlas based segmentation; and (2) aSSM based fitting is used to preserve hip joint structure and to avoid penetration between the pelvic and femoral models. Taking manual segmentation as the ground truth, we evaluated the present approach on 30 hip CT images (60 hips) with a 6-fold cross validation. When the present approach was compared to manual segmentation, a mean segmentation accuracy of 0.40, 0.36, and 0.36 mm was found for the pelvis, the left proximal femur, and the right proximal femur, respectively. When the models derived from both segmentations were used to compute the PAO diagnosis parameters, a difference of 2.0 ± 1.5°, 2.1 ± 1.6°, and 3.5 ± 2.3% were found for anteversion, inclination, and acetabular coverage, respectively. The achieved accuracy is regarded as clinically accurate enough for our target applications
Fast and Robust Femur Segmentation from Computed Tomography Images for Patient-Specific Hip Fracture Risk Screening
Osteoporosis is a common bone disease that increases the risk of bone
fracture. Hip-fracture risk screening methods based on finite element analysis
depend on segmented computed tomography (CT) images; however, current femur
segmentation methods require manual delineations of large data sets. Here we
propose a deep neural network for fully automated, accurate, and fast
segmentation of the proximal femur from CT. Evaluation on a set of 1147
proximal femurs with ground truth segmentations demonstrates that our method is
apt for hip-fracture risk screening, bringing us one step closer to a
clinically viable option for screening at-risk patients for hip-fracture
susceptibility.Comment: This article has been accepted for publication in Computer Methods in
Biomechanics and Biomedical Engineering: Imaging & Visualization, published
by Taylor & Franci
A fast and robust patient specific Finite Element mesh registration technique: application to 60 clinical cases
Finite Element mesh generation remains an important issue for patient
specific biomechanical modeling. While some techniques make automatic mesh
generation possible, in most cases, manual mesh generation is preferred for
better control over the sub-domain representation, element type, layout and
refinement that it provides. Yet, this option is time consuming and not suited
for intraoperative situations where model generation and computation time is
critical. To overcome this problem we propose a fast and automatic mesh
generation technique based on the elastic registration of a generic mesh to the
specific target organ in conjunction with element regularity and quality
correction. This Mesh-Match-and-Repair (MMRep) approach combines control over
the mesh structure along with fast and robust meshing capabilities, even in
situations where only partial organ geometry is available. The technique was
successfully tested on a database of 5 pre-operatively acquired complete femora
CT scans, 5 femoral heads partially digitized at intraoperative stage, and 50
CT volumes of patients' heads. The MMRep algorithm succeeded in all 60 cases,
yielding for each patient a hex-dominant, Atlas based, Finite Element mesh with
submillimetric surface representation accuracy, directly exploitable within a
commercial FE software
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