Acoustic and videoendoscopic techniques to improve voice assessment via relative fundamental frequency

Quantitative measures of laryngeal muscle tension are needed to improve assessment and track clinical progress. Although relative fundamental frequency (RFF) shows promise as an acoustic estimate of laryngeal muscle tension, it is not yet transferable to the clinic. The purpose of this work was to refine algorithmic estimation of RFF, as well as to enhance the knowledge surrounding the physiological underpinnings of RFF. The first study used a large database of voice samples collected from 227 speakers with voice disorders and 256 typical speakers to evaluate the effects of fundamental frequency estimation techniques and voice sample characteristics on algorithmic RFF estimation. By refining fundamental frequency estimation using the Auditory Sawtooth Waveform Inspired Pitch Estimator—Prime (Auditory-SWIPE′) algorithm and accounting for sample characteristics via the acoustic measure, pitch strength, algorithmic errors related to the accuracy and precision of RFF were reduced by 88.4% and 17.3%, respectively. The second study sought to characterize the physiological factors influencing acoustic outputs of RFF estimation. A group of 53 speakers with voice disorders and 69 typical speakers each produced the utterance, /ifi/, while simultaneous recordings were collected using a microphone and flexible nasendoscope. Acoustic features calculated via the microphone signal were examined in reference to the physiological initiation and termination of vocal fold vibration. The features that corresponded with these transitions were then implemented into the RFF algorithm, leading to significant improvements in the precision of the RFF algorithm to reflect the underlying physiological mechanisms for voicing offsets (p < .001, V = .60) and onsets (p < .001, V = .54) when compared to manual RFF estimation. The third study further elucidated the physiological underpinnings of RFF by examining the contribution of vocal fold abduction to RFF during intervocalic voicing offsets. Vocal fold abductory patterns were compared to RFF values in a subset of speakers from the second study, comprising young adults, older adults, and older adults with Parkinson’s disease. Abductory patterns were not significantly different among the three groups; however, vocal fold abduction was observed to play a significant role in measures of RFF at voicing offset. By improving algorithmic estimation and elucidating aspects of the underlying physiology affecting RFF, this work adds to the utility of RFF for use in conjunction with current clinical techniques to assess laryngeal muscle tension.2021-09-29T00:00:00

Empowering patients in self-management of parkinson's disease through cooperative ICT systems

The objective of this chapter is to demonstrate the technical feasibility and medical effectiveness of personalised services and care programmes for Parkinson's disease, based on the combination of mHealth applications, cooperative ICTs, cloud technologies and wearable integrated devices, which empower patients to manage their health and disease in cooperation with their formal and informal caregivers, and with professional medical staff across different care settings, such as hospital and home. The presented service revolves around the use of two wearable inertial sensors, i.e. SensFoot and SensHand, for measuring foot and hand performance in the MDS-UPDRS III motor exercises. The devices were tested in medical settings with eight patients, eight hyposmic subjects and eight healthy controls, and the results demonstrated that this approach allows quantitative metrics for objective evaluation to be measured, in order to identify pre-motor/pre-clinical diagnosis and to provide a complete service of tele-health with remote control provided by cloud technologies. © 2016, IGI Global. All rights reserved