Reflectance Transformation Imaging (RTI) System for Ancient Documentary Artefacts

This tutorial summarises our uses of reflectance transformation imaging in archaeological contexts. It introduces the UK AHRC funded project reflectance Transformation Imaging for Anciant Documentary Artefacts and demonstrates imaging methodologies

Focusing on out-of-focus : assessing defocus estimation algorithms for the benefit of automated image masking

Acquiring photographs as input for an image-based modelling pipeline is less trivial than often assumed. Photographs should be correctly exposed, cover the subject sufficiently from all possible angles, have the required spatial resolution, be devoid of any motion blur, exhibit accurate focus and feature an adequate depth of field. The last four characteristics all determine the " sharpness " of an image and the photogrammetric, computer vision and hybrid photogrammetric computer vision communities all assume that the object to be modelled is depicted " acceptably " sharp throughout the whole image collection. Although none of these three fields has ever properly quantified " acceptably sharp " , it is more or less standard practice to mask those image portions that appear to be unsharp due to the limited depth of field around the plane of focus (whether this means blurry object parts or completely out-of-focus backgrounds). This paper will assess how well-or ill-suited defocus estimating algorithms are for automatically masking a series of photographs, since this could speed up modelling pipelines with many hundreds or thousands of photographs. To that end, the paper uses five different real-world datasets and compares the output of three state-of-the-art edge-based defocus estimators. Afterwards, critical comments and plans for the future finalise this paper

Prospects for Theranostics in Neurosurgical Imaging: Empowering Confocal Laser Endomicroscopy Diagnostics via Deep Learning

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence imaging technology that has the potential to increase intraoperative precision, extend resection, and tailor surgery for malignant invasive brain tumors because of its subcellular dimension resolution. Despite its promising diagnostic potential, interpreting the gray tone fluorescence images can be difficult for untrained users. In this review, we provide a detailed description of bioinformatical analysis methodology of CLE images that begins to assist the neurosurgeon and pathologist to rapidly connect on-the-fly intraoperative imaging, pathology, and surgical observation into a conclusionary system within the concept of theranostics. We present an overview and discuss deep learning models for automatic detection of the diagnostic CLE images and discuss various training regimes and ensemble modeling effect on the power of deep learning predictive models. Two major approaches reviewed in this paper include the models that can automatically classify CLE images into diagnostic/nondiagnostic, glioma/nonglioma, tumor/injury/normal categories and models that can localize histological features on the CLE images using weakly supervised methods. We also briefly review advances in the deep learning approaches used for CLE image analysis in other organs. Significant advances in speed and precision of automated diagnostic frame selection would augment the diagnostic potential of CLE, improve operative workflow and integration into brain tumor surgery. Such technology and bioinformatics analytics lend themselves to improved precision, personalization, and theranostics in brain tumor treatment.Comment: See the final version published in Frontiers in Oncology here: https://www.frontiersin.org/articles/10.3389/fonc.2018.00240/ful

Rethinking the Pipeline of Demosaicing, Denoising and Super-Resolution

Incomplete color sampling, noise degradation, and limited resolution are the three key problems that are unavoidable in modern camera systems. Demosaicing (DM), denoising (DN), and super-resolution (SR) are core components in a digital image processing pipeline to overcome the three problems above, respectively. Although each of these problems has been studied actively, the mixture problem of DM, DN, and SR, which is a higher practical value, lacks enough attention. Such a mixture problem is usually solved by a sequential solution (applying each method independently in a fixed order: DM $\to$ DN $\to$ SR), or is simply tackled by an end-to-end network without enough analysis into interactions among tasks, resulting in an undesired performance drop in the final image quality. In this paper, we rethink the mixture problem from a holistic perspective and propose a new image processing pipeline: DN $\to$ SR $\to$ DM. Extensive experiments show that simply modifying the usual sequential solution by leveraging our proposed pipeline could enhance the image quality by a large margin. We further adopt the proposed pipeline into an end-to-end network, and present Trinity Enhancement Network (TENet). Quantitative and qualitative experiments demonstrate the superiority of our TENet to the state-of-the-art. Besides, we notice the literature lacks a full color sampled dataset. To this end, we contribute a new high-quality full color sampled real-world dataset, namely PixelShift200. Our experiments show the benefit of the proposed PixelShift200 dataset for raw image processing.Comment: Code is available at: https://github.com/guochengqian/TENe