The effect of exposure to radiofrequency fields on cancer risk in the general and working population: a protocol for a systematic review of human observational studies

BACKGROUND: The World Health Organization (WHO) has an ongoing project to assess potential health effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in the general and working population. Here we present the protocol for a systematic review of the scientific literature on cancer hazards from exposure to RF-EMF in humans, commissioned by the WHO as part of that project. OBJECTIVE: To assess the quality and strength of the evidence provided by human observational studies for a causal association between exposure to RF-EMF and risk of neoplastic diseases. ELIGIBILITY CRITERIA: We will include cohort and case-control studies investigating neoplasia risks in relation to three types of exposure to RF-EMF: near-field, head-localized, exposure from wireless phone use (SR-A); far-field, whole body, environmental exposure from fixed-site transmitters (SR-B); near/far-field occupational exposures from use of handheld transceivers or RF-emitting equipment in the workplace (SR-C). While no restriction on tumour type will be applied, we will focus on selected neoplasms of the central nervous system (brain, meninges, pituitary gland, acoustic nerve) and salivary gland tumours (SR-A); brain tumours and leukaemias (SR-B, SR-C). INFORMATION SOURCES: Eligible studies will be identified through Medline, Embase, and EMF-Portal. RISK-OF-BIAS ASSESSMENT: We will use a tailored version of the OHAT's tool to evaluate the study's internal validity. DATA SYNTHESIS: We will consider separately studies on different tumours, neoplasm-specific risks from different exposure sources, and a given exposure-outcome pair in adults and children. When a quantitative synthesis of findings can be envisaged, the main aims of the meta-analysis will be to assess the strength of association and the shape of the exposure-response relationship; to quantify the degree of heterogeneity across studies; and explore the sources of inconsistency (if any). When a meta-analysis is judged inappropriate, we will perform a narrative synthesis, complemented by a structured tabulation of results and appropriate visual displays. EVIDENCE ASSESSMENT: Confidence in evidence will be assessed in line with the GRADE approach. FUNDING: This project is supported by the World Health Organization. Co-financing was provided by the New Zealand Ministry of Health; the Istituto Superiore di Sanita in its capacity as a WHO Collaborating Centre for Radiation and Health; ARPANSA as a WHO Collaborating Centre for Radiation Protection. REGISTRATION: PROSPERO CRD42021236798

Personal exposure to radiofrequency electromagnetic fields among palestinian adults

This work deals with the assessment of personal exposure to radiofrequency electromagnetic fields and the study of temporal and spatial daily variations in a group of 24 adults from the West Bank, Palestine. Exposure was measured using a personal exposure meter EME SPY 140. Mean values of exposure levels from different radiofrequency sources were calculated using both naive and robust regression on order statistics approaches. The total daily exposure from all radiofrequency electromagnetic field sources varied widelyamong participants depending on their location, the mobile network they use, their activities, and their mode of transportation, ranging from about 0.2 V m−1 to 0.9 V m−1. The average total daily exposure of all participants was about 0.48 V m−1. The main contribution to the mean exposure was from WiFi 2G (45%), GSM900 uplink (19%), GSM900 downlink, and FM radiobroadcasting (each by 11%). Other sources including GSM1800, UMTS2100, WiFi 5G, DECT, TETRA, WiMAX, and TV bands all together contributed 14%. During different activities, participants were exposed to the highest exposure level while traveling and to the lowest exposure while they were sleeping. During the day, participants received the highest exposure during the time period from 1600 to 2400 h. Based on thermal effect of radiofrequency electromagnetic fields, all evaluated personal exposures comply with guidelines recommended for the general public by the International Commission on Non-Ionizing Radiation Protection. Health Phys. 117(4):396–402; 201

Effects of radiofrequency electromagnetic field exposure on sleep quality

The use of wireless communication devices, which emit radiofrequency electromagnetic fields (RF-EMF), has increased in the past decades. According to the World Health Organization (WHO) mobile phone use is ubiquitous with an estimated 4.6 billion subscriptions globally. The missing knowledge about a biological mechanism and the attribution of non-specific symptoms of ill health to RF-EMF has led to an increased public concern about possible adverse health effects from this radiation. One of the most often reported symptoms due to RF-EMF exposure are sleep disturbances. In several randomised double-blind human laboratory studies, changes in the sleep electroencephalogram (EEG) after exposure to RF-EMF were observed. The impact of these small changes on sleep quality and therefore on general well-being is unclear. Previous epidemiological studies have used a cross-sectional design, which is not appropriate for establishing causal relationships between exposure and outcome. Studies with a cohort design are therefore needed. Additionally, exposure assessment was mostly inadequate or only parts of the real exposure situation were taken into account. Personal measurement devices (exposimeters) have become available a few years age. In large epidemiological studies, it is very time-consuming and costly to use such devices. Other exposure assessment methods are therefore needed. The main aim of this thesis was to investigate the association between personal RF-EMF exposure and sleep quality by using objective as well as subjective data. To predict personal exposure to RF-EMF a comprehensive exposure assessment method was applied. This thesis was part of the QUALIFEX project (a prospective cohort study on radiofrequency electromagnetic field exposure and health related quality of life) which is embedded in the National Research Program 57 (NRP-57) about non-ionising radiation. The health effect of RF-EMF exposure was investigated in a cohort study which consisted of a baseline survey in May 2008 and a follow-up survey one year later. Questionnaires entitled „Environment and Health“ were sent out to 1375 randomly selected study participants in the region of Basel (Switzerland). Information on sleep quality, on exposure relevant factors and on various confounding factors was collected. By means of a pre-study, which was not part of this thesis, a comprehensive exposure assessment method was developed. To predict personal exposure to far-field RF-EMF (e.g mobile phone base stations or radio transmitters), a validated full exposure prediction model was used which was developed based personal exposure measurements of 166 study participants who took part in a pre-study. Exposure to close to body sources was assessed using self-reported data on mobile phone and cordless phone use. Objective data of mobile phone use from network operators for participants who gave informed consent were additionally collected. For a nested sleep study, 120 participants out of the baseline survey took part in a nested sleep study to verify our previous results. Sleep quality and sleep behavior was assessed using actigraphy and exposure to RF-EMF was measured by means of personal exposimeters. For the baseline survey, mean calculated RF-EMF exposure to all relevant sources of all 1375 study participants was 0.12 mW/m2 (0.21 V/m). Exposure at the follow-up survey was 0.13 mW/m2 (0.22 V/m) and therefore comparable with the baseline exposure. No consistent association between RF-EMF exposure and self-reported sleep quality neither in the baseline analysis (cross-sectional analysis) nor in the cohort analysis (longitudinal analysis) was observed. In the nested sleep study, objective data on exposure and sleep quality did not yield any association between exposure and sleep quality. The QUALIFEX project was the first study which applied a cohort design to investigate the association between RF-EMF exposure and sleep quality. Additionally, we were able to verify our results of the cohort study with objective data obtained in a nested sleep study. Overall, we found no consistent association between self-reported as well as objectively measured sleep quality and exposure to relevant RF-EMF sources in everyday life. Our results increase the evidence for a true absence of an effect of RF-EMF exposure on sleep quality. Our study used a very comprehensive exposure assessment method which included far-field sources as well as close to body sources. In general, exposure levels were very small and changes between the baseline and the follow-up survey were marginal. Hence, with our study no conclusions can be drawn regarding potential health effects of higher exposure levels. In future studies, more data on long-term effects have to be collected. Additionally, the exposure situation in everyday life should be monitored because new technologies operating with RF-EMF are continuously arising

Long term variations measurement of electromagnetic field exposures in Alcalá de Henares (Spain)

Electromagnetic radiowave exposure is a major concern in most countries due to possible adverse health effects. Over the last 10 years, many technological changes (digital television, mobile technologies, wireless networks…) have led to variations in the electromagnetic field (EMF) levels. A large number of studies devoted to the analysis of EMF levels with personal dosimeters or computer models of the exposure of mobile stations have been conducted. However, the study of the exposure values, taking into account all the existing sources, and their evolution in a wide area, using measurements, has rarely been performed. In this paper, we provide a comparison of the EMF exposure levels for the city of Alcalá de Henares (Spain) over a ten-year period using a broadband isotropic probe in the range from 100 kHz to 3 GHz. A statistical and spatial analysis of the measurements and their variations are also presented for the study of the global and local variations. The measured values in the period from 2006 to 2015 were ranging from 0.02 to 2.05 V/m. Our global results show a moderate increase from 2006 to 2010 and they are almost invariant from 2010 to 2015. Although the whole dataset does not have relevant statistical difference, we have found marked local differences. In the city areas where the population density has remained unaltered, we have measured lower exposure levels. Conversely, new urban and industrial developments have demanded new resources, which have potentially contributed to the observed increase in the measured electric field levels within these areas

Constructing an EMF radiation Hygeia framework and model to demonstrate a public interest override

Scientific views on EMF radiation dosimetry and models increasingly suggest that even a tiny increase in the incidence of diseases resulting from exposure to EMF radiation could have broad¹ implications for public health, social accounting and the economy. In South Africa (SA) there is no national EMF radiation exposure protection standard, statutory monitoring or regulations. Multinational High Court deliberations indicate the need for public interest EMF radiation exposure protection standards in South Africa. Domestic citizens, academics, as well as regulatory and legislative practitioners, are unable to effectively monitor and investigate EMF radiation exposure emissions from infrastructure sources, because industries refuse to provide the required data. Industries have, since 2003, continually obstructed access to the data and the establishment of a national EMF radiation standard, citing that it would be in conflict with their strategic economic interests. The demonstration of a public interest override (PIO) function is legislatively required to gain access to the required data. This study constructed (1) a framework and (2) a model to perform test simulations against the (3) PIO criteria to demonstrate a PIO function and tested one PIO simulation scenario. Testing the PIO scenario firstly required the construction of a public interest framework, drawing input from multiple disciplines. The framework literature review used systematic case law and scientific-technical analysis whilst the framework science sought to understand the connections, feedbacks, and trajectories that occur as a result of natural and human system processes and exchanges. The EMF radiation exposure system functions to support human wellbeing needs and to explore the benefits and losses associated with alternative futures with the goal to uncover the current and future limits thereof. In the second instance a HYGEIA² model was selected as a base investigation and forecast simulation tool. The study had to uncover the key attributes and parameters necessary to construct and to run successful EMF radiation exposure simulations. Thereafter the HYGEIA model was modified to specifically identify and evaluate EMF radiation exposure hazard conditions. Through subsequent simulation runs, the constructed framework was then tested. Requested anthroposphere information was synthesized within a systems model to forecast ecosystem services and human-use dynamics under alternative scenarios. The simulation used the model, the model references and the framework for guidelines, thus allowing multiple simulation / demonstration runs for different contexts or scenarios. The third step was the construction of a PIO checklist which guides criteria testing and provides a means of gaining pertinent information for further studies, based on this dissertation. Framework EMF radiation policy inputs into the model were intersected with identified vulnerable area facilities which were selected based on international criteria. The research output revealed potential EMF radiation violations which served as system feedback inputs in support of a demonstrated PIO function. The research recommends that the identified EMF radiation exposure violations of public health undergo a Promotion of Access to Information Act (PAIA) judicial review process to confirm the research findings. The judicial qualification of a PAIA PIO function of ‘substances released into the environment’ and ‘public safety or environmental risk’ would enable access to EMF radiation emissions data essential to future studies

Minimization of measuring points for the electric field exposure map generation in indoor environments by means of Kriging interpolation and selective sampling

In a world with increasing systems accessing to radio spectrum, the concern for exposure to electromagnetic fields is growing and therefore it is necessary to check limits in those areas where electromagnetic sources are working. Therefore, radio and exposure maps are continuously being generated, mainly in outdoor areas, by using many interpolation techniques. In this work, Surfer software and Kriging interpolation have been used for the first time to generate an indoor exposure map. A regular measuring mesh has been generated. Elimination of Less Significant Points (ELSP) and Geometrical Elimination of Neighbors (GEN) strategies to reduce the measuring points have been presented and evaluated. Both strategies have been compared to the map generated with all the measurements by calculating the root mean square and mean absolute errors. Results indicate that ELSP method can reduce up to 70% of the mesh measuring points while producing similar exposure maps to the one generated with all the measuring points. GEN, however, produces distorted maps and much higher error indicators even for 50% of eliminated measuring points. As a conclusion, a procedure for reducing the measuring points to generate radio and exposure maps is proposed based on the ELSP method and the Kriging interpolation.This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors

Epidemiology of Health Effects of Radiofrequency Exposure

We have undertaken a comprehensive review of epidemiologic studies about the effects of radiofrequency fields (RFs) on human health in order to summarize the current state of knowledge, explain the methodologic issues that are involved, and aid in the planning of future studies. There have been a large number of occupational studies over several decades, particularly on cancer, cardiovascular disease, adverse reproductive outcome, and cataract, in relation to RF exposure. More recently, there have been studies of residential exposure, mainly from radio and television transmitters, and especially focusing on leukemia. There have also been studies of mobile telephone users, particularly on brain tumors and less often on other cancers and on symptoms. Results of these studies to date give no consistent or convincing evidence of a causal relation between RF exposure and any adverse health effect. On the other hand, the studies have too many deficiencies to rule out an association. A key concern across all studies is the quality of assessment of RF exposure. Despite the ubiquity of new technologies using RFs, little is known about population exposure from RF sources and even less about the relative importance of different sources. Other cautions are that mobile phone studies to date have been able to address only relatively short lag periods, that almost no data are available on the consequences of childhood exposure, and that published data largely concentrate on a small number of outcomes, especially brain tumor and leukemia

A Survey of Positioning Systems Using Visible LED Lights

© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.As Global Positioning System (GPS) cannot provide satisfying performance in indoor environments, indoor positioning technology, which utilizes indoor wireless signals instead of GPS signals, has grown rapidly in recent years. Meanwhile, visible light communication (VLC) using light devices such as light emitting diodes (LEDs) has been deemed to be a promising candidate in the heterogeneous wireless networks that may collaborate with radio frequencies (RF) wireless networks. In particular, light-fidelity has a great potential for deployment in future indoor environments because of its high throughput and security advantages. This paper provides a comprehensive study of a novel positioning technology based on visible white LED lights, which has attracted much attention from both academia and industry. The essential characteristics and principles of this system are deeply discussed, and relevant positioning algorithms and designs are classified and elaborated. This paper undertakes a thorough investigation into current LED-based indoor positioning systems and compares their performance through many aspects, such as test environment, accuracy, and cost. It presents indoor hybrid positioning systems among VLC and other systems (e.g., inertial sensors and RF systems). We also review and classify outdoor VLC positioning applications for the first time. Finally, this paper surveys major advances as well as open issues, challenges, and future research directions in VLC positioning systems.Peer reviewe