86 research outputs found
Bipolar Disorder Predictive Model: A Study to Analyze and Predict Emotional Change Using Physiological Signals
University of Minnesota M.S. thesis. July 2019. Major: Computer Science. Advisor: Arshia Khan. 1 computer file (PDF); viii, 95 pages.Bipolar disorder, a chronic mental illness, most common among people of ages 18 years and older, affects over 2.6 percent of the United States population alone. Although this illness cannot be cured, it can be managed by continuous tracking and monitoring. Hence, if a manic or depressive episode can be identified or predicted in its early stages, severe damage can be minimized, if not prevented. This thesis proposes the design of an objective sensor based system that is based on physiological predictors for the continuous and autonomous monitoring of bipolar patients. This system consists of a pulse rate sensor to record heart rate, and an electrodermal activity sensor to trace the emotional and cognitive state changes and does not rely completely on self-assessment or reporting. Furthermore, it investigates how psychological changes affect physiological responses, such as Heart rate variability (HRV) and Electrodermal activity (EDA). We conducted a study with 50 healthy participants, where each participant was subjected to a certain degree of image and audio induced emotion. Baseline and the emotional stimuli data was collected. Time- domain and non-linear analysis of HRV was then performed on the collected HRV data. In addition, EDA data analysis was performed by decomposing it into tonic and phasic components. We investigated the ability of HRV and EDA to identify the activity of the au- tonomic nervous system in response to emotional stimuli. Moreover, the extracted features from the data were then used to build machine learning models to predict the given psychological change in response to the emotional stimuli. Our results showed that these combination of HRV and EDA features from the study we conducted yielded an average accuracy of up to 73% with Support vector machine, and 68.3% with Discriminant analysis for predicting emotional change in healthy individuals
Recommended from our members
Wearable, Environmental, and Smartphone-Based Passive Sensing for Mental Health Monitoring
Collecting and analyzing data from sensors embedded in the context of daily life has been widely employed for the monitoring of mental health. Variations in parameters such as movement, sleep duration, heart rate, electrocardiogram, skin temperature, etc., are often associated with psychiatric disorders. Namely, accelerometer data, microphone, and call logs can be utilized to identify voice features and social activities indicative of depressive symptoms, and physiological factors such as heart rate and skin conductance can be used to detect stress and anxiety disorders. Therefore, a wide range of devices comprising a variety of sensors have been developed to capture these physiological and behavioral data and translate them into phenotypes and states related to mental health. Such systems aim to identify behaviors that are the consequence of an underlying physiological alteration, and hence, the raw sensor data are captured and converted into features that are used to define behavioral markers, often through machine learning. However, due to the complexity of passive data, these relationships are not simple and need to be well-established. Furthermore, parameters such as intrapersonal and interpersonal differences need to be considered when interpreting the data. Altogether, combining practical mobile and wearable systems with the right data analysis algorithms can provide a useful tool for the monitoring and management of mental disorders. The current review aims to comprehensively present and critically discuss all available smartphone-based, wearable, and environmental sensors for detecting such parameters in relation to the treatment and/or management of the most common mental health conditions
Learning Biosignals with Deep Learning
The healthcare system, which is ubiquitously recognized as one of the most influential
system in society, is facing new challenges since the start of the decade.The myriad of
physiological data generated by individuals, namely in the healthcare system, is generating
a burden on physicians, losing effectiveness on the collection of patient data. Information
systems and, in particular, novel deep learning (DL) algorithms have been prompting a
way to take this problem.
This thesis has the aim to have an impact in biosignal research and industry by
presenting DL solutions that could empower this field. For this purpose an extensive study
of how to incorporate and implement Convolutional Neural Networks (CNN), Recursive
Neural Networks (RNN) and Fully Connected Networks in biosignal studies is discussed.
Different architecture configurations were explored for signal processing and decision
making and were implemented in three different scenarios: (1) Biosignal learning and
synthesis; (2) Electrocardiogram (ECG) biometric systems, and; (3) Electrocardiogram
(ECG) anomaly detection systems. In (1) a RNN-based architecture was able to replicate
autonomously three types of biosignals with a high degree of confidence. As for (2) three
CNN-based architectures, and a RNN-based architecture (same used in (1)) were used
for both biometric identification, reaching values above 90% for electrode-base datasets
(Fantasia, ECG-ID and MIT-BIH) and 75% for off-person dataset (CYBHi), and biometric
authentication, achieving Equal Error Rates (EER) of near 0% for Fantasia and MIT-BIH
and bellow 4% for CYBHi. As for (3) the abstraction of healthy clean the ECG signal
and detection of its deviation was made and tested in two different scenarios: presence of
noise using autoencoder and fully-connected network (reaching 99% accuracy for binary
classification and 71% for multi-class), and; arrhythmia events by including a RNN to the
previous architecture (57% accuracy and 61% sensitivity).
In sum, these systems are shown to be capable of producing novel results. The incorporation
of several AI systems into one could provide to be the next generation of
preventive medicine, as the machines have access to different physiological and anatomical
states, it could produce more informed solutions for the issues that one may face in the
future increasing the performance of autonomous preventing systems that could be used
in every-day life in remote places where the access to medicine is limited. These systems will also help the study of the signal behaviour and how they are made in real life context
as explainable AI could trigger this perception and link the inner states of a network with
the biological traits.O sistema de saúde, que é ubiquamente reconhecido como um dos sistemas mais influentes
da sociedade, enfrenta novos desafios desde o ínicio da década. A miríade de dados fisiológicos
gerados por indíviduos, nomeadamente no sistema de saúde, está a gerar um fardo
para os médicos, perdendo a eficiência no conjunto dos dados do paciente. Os sistemas de
informação e, mais espcificamente, da inovação de algoritmos de aprendizagem profunda
(DL) têm sido usados na procura de uma solução para este problema.
Esta tese tem o objetivo de ter um impacto na pesquisa e na indústria de biosinais,
apresentando soluções de DL que poderiam melhorar esta área de investigação. Para
esse fim, é discutido um extenso estudo de como incorporar e implementar redes neurais
convolucionais (CNN), redes neurais recursivas (RNN) e redes totalmente conectadas para
o estudo de biosinais.
Diferentes arquiteturas foram exploradas para processamento e tomada de decisão de
sinais e foram implementadas em três cenários diferentes: (1) Aprendizagem e síntese de
biosinais; (2) sistemas biométricos com o uso de eletrocardiograma (ECG), e; (3) Sistema
de detecção de anomalias no ECG. Em (1) uma arquitetura baseada na RNN foi capaz
de replicar autonomamente três tipos de sinais biológicos com um alto grau de confiança.
Quanto a (2) três arquiteturas baseadas em CNN e uma arquitetura baseada em RNN
(a mesma usada em (1)) foram usadas para ambas as identificações, atingindo valores
acima de 90 % para conjuntos de dados à base de eletrodos (Fantasia, ECG-ID e MIT
-BIH) e 75 % para o conjunto de dados fora da pessoa (CYBHi) e autenticação, atingindo
taxas de erro iguais (EER) de quase 0 % para Fantasia e MIT-BIH e abaixo de 4 % para
CYBHi. Quanto a (3) a abstração de sinais limpos e assimptomáticos de ECG e a detecção
do seu desvio foram feitas e testadas em dois cenários diferentes: na presença de ruído
usando um autocodificador e uma rede totalmente conectada (atingindo 99 % de precisão
na classificação binária e 71 % na multi-classe), e; eventos de arritmia incluindo um RNN
na arquitetura anterior (57 % de precisão e 61 % de sensibilidade).
Em suma, esses sistemas são mais uma vez demonstrados como capazes de produzir
resultados inovadores. A incorporação de vários sistemas de inteligência artificial em
um unico sistema pederá desencadear a próxima geração de medicina preventiva. Os
algoritmos ao terem acesso a diferentes estados fisiológicos e anatómicos, podem produzir
soluções mais informadas para os problemas que se possam enfrentar no futuro, aumentando o desempenho de sistemas autónomos de prevenção que poderiam ser usados na vida
quotidiana, nomeadamente em locais remotos onde o acesso à medicinas é limitado. Estes
sistemas também ajudarão o estudo do comportamento do sinal e como eles são feitos no
contexto da vida real, pois a IA explicável pode desencadear essa percepção e vincular os
estados internos de uma rede às características biológicas
Earables: Wearable Computing on the Ears
Kopfhörer haben sich bei Verbrauchern durchgesetzt, da sie private Audiokanäle anbieten, zum Beispiel zum Hören von Musik, zum Anschauen der neuesten Filme während dem Pendeln oder zum freihändigen Telefonieren. Dank diesem eindeutigen primären Einsatzzweck haben sich Kopfhörer im Vergleich zu anderen Wearables, wie zum Beispiel Smartglasses, bereits stärker durchgesetzt. In den letzten Jahren hat sich eine neue Klasse von Wearables herausgebildet, die als "Earables" bezeichnet werden. Diese Geräte sind so konzipiert, dass sie in oder um die Ohren getragen werden können. Sie enthalten verschiedene Sensoren, um die Funktionalität von Kopfhörern zu erweitern. Die räumliche Nähe von Earables zu wichtigen anatomischen Strukturen des menschlichen Körpers bietet eine ausgezeichnete Plattform für die Erfassung einer Vielzahl von Eigenschaften, Prozessen und Aktivitäten.
Auch wenn im Bereich der Earables-Forschung bereits einige Fortschritte erzielt wurden, wird deren Potenzial aktuell nicht vollständig abgeschöpft. Ziel dieser Dissertation ist es daher, neue Einblicke in die Möglichkeiten von Earables zu geben, indem fortschrittliche Sensorikansätze erforscht werden, welche die Erkennung von bisher unzugänglichen Phänomenen ermöglichen. Durch die Einführung von neuartiger Hardware und Algorithmik zielt diese Dissertation darauf ab, die Grenzen des Erreichbaren im Bereich Earables zu verschieben und diese letztlich als vielseitige Sensorplattform zur Erweiterung menschlicher Fähigkeiten zu etablieren.
Um eine fundierte Grundlage für die Dissertation zu schaffen, synthetisiert die vorliegende Arbeit den Stand der Technik im Bereich der ohr-basierten Sensorik und stellt eine einzigartig umfassende Taxonomie auf der Basis von 271 relevanten Publikationen vor. Durch die Verbindung von Low-Level-Sensor-Prinzipien mit Higher-Level-Phänomenen werden in der Dissertation anschließ-end Arbeiten aus verschiedenen Bereichen zusammengefasst, darunter (i) physiologische Überwachung und Gesundheit, (ii) Bewegung und Aktivität, (iii) Interaktion und (iv) Authentifizierung und Identifizierung.
Diese Dissertation baut auf der bestehenden Forschung im Bereich der physiologischen Überwachung und Gesundheit mit Hilfe von Earables auf und stellt fortschrittliche Algorithmen, statistische Auswertungen und empirische Studien vor, um die Machbarkeit der Messung der Atemfrequenz und der Erkennung von Episoden erhöhter Hustenfrequenz durch den Einsatz von In-Ear-Beschleunigungsmessern und Gyroskopen zu demonstrieren. Diese neuartigen Sensorfunktionen unterstreichen das Potenzial von Earables, einen gesünderen Lebensstil zu fördern und eine proaktive Gesundheitsversorgung zu ermöglichen.
Darüber hinaus wird in dieser Dissertation ein innovativer Eye-Tracking-Ansatz namens "earEOG" vorgestellt, welcher Aktivitätserkennung erleichtern soll. Durch die systematische Auswertung von Elektrodenpotentialen, die um die Ohren herum mittels eines modifizierten Kopfhörers gemessen werden, eröffnet diese Dissertation einen neuen Weg zur Messung der Blickrichtung. Dabei ist das Verfahren weniger aufdringlich und komfortabler als bisherige Ansätze. Darüber hinaus wird ein Regressionsmodell eingeführt, um absolute Änderungen des Blickwinkels auf der Grundlage von earEOG vorherzusagen. Diese Entwicklung eröffnet neue Möglichkeiten für Forschung, welche sich nahtlos in das tägliche Leben integrieren lässt und tiefere Einblicke in das menschliche Verhalten ermöglicht. Weiterhin zeigt diese Arbeit, wie sich die einzigarte Bauform von Earables mit Sensorik kombinieren lässt, um neuartige Phänomene zu erkennen.
Um die Interaktionsmöglichkeiten von Earables zu verbessern, wird in dieser Dissertation eine diskrete Eingabetechnik namens "EarRumble" vorgestellt, die auf der freiwilligen Kontrolle des Tensor Tympani Muskels im Mittelohr beruht. Die Dissertation bietet Einblicke in die Verbreitung, die Benutzerfreundlichkeit und den Komfort von EarRumble, zusammen mit praktischen Anwendungen in zwei realen Szenarien. Der EarRumble-Ansatz erweitert das Ohr von einem rein rezeptiven Organ zu einem Organ, das nicht nur Signale empfangen, sondern auch Ausgangssignale erzeugen kann. Im Wesentlichen wird das Ohr als zusätzliches interaktives Medium eingesetzt, welches eine freihändige und augenfreie Kommunikation zwischen Mensch und Maschine ermöglicht. EarRumble stellt eine Interaktionstechnik vor, die von den Nutzern als "magisch und fast telepathisch" beschrieben wird, und zeigt ein erhebliches ungenutztes Potenzial im Bereich der Earables auf.
Aufbauend auf den vorhergehenden Ergebnissen der verschiedenen Anwendungsbereiche und Forschungserkenntnisse mündet die Dissertation in einer offenen Hard- und Software-Plattform für Earables namens "OpenEarable". OpenEarable umfasst eine Reihe fortschrittlicher Sensorfunktionen, die für verschiedene ohrbasierte Forschungsanwendungen geeignet sind, und ist gleichzeitig einfach herzustellen. Hierdurch werden die Einstiegshürden in die ohrbasierte Sensorforschung gesenkt und OpenEarable trägt somit dazu bei, das gesamte Potenzial von Earables auszuschöpfen. Darüber hinaus trägt die Dissertation grundlegenden Designrichtlinien und Referenzarchitekturen für Earables bei. Durch diese Forschung schließt die Dissertation die Lücke zwischen der Grundlagenforschung zu ohrbasierten Sensoren und deren praktischem Einsatz in realen Szenarien.
Zusammenfassend liefert die Dissertation neue Nutzungsszenarien, Algorithmen, Hardware-Prototypen, statistische Auswertungen, empirische Studien und Designrichtlinien, um das Feld des Earable Computing voranzutreiben. Darüber hinaus erweitert diese Dissertation den traditionellen Anwendungsbereich von Kopfhörern, indem sie die auf Audio fokussierten Geräte zu einer Plattform erweitert, welche eine Vielzahl fortschrittlicher Sensorfähigkeiten bietet, um Eigenschaften, Prozesse und Aktivitäten zu erfassen. Diese Neuausrichtung ermöglicht es Earables sich als bedeutende Wearable Kategorie zu etablieren, und die Vision von Earables als eine vielseitige Sensorenplattform zur Erweiterung der menschlichen Fähigkeiten wird somit zunehmend realer
Modern Views of Machine Learning for Precision Psychiatry
In light of the NIMH's Research Domain Criteria (RDoC), the advent of
functional neuroimaging, novel technologies and methods provide new
opportunities to develop precise and personalized prognosis and diagnosis of
mental disorders. Machine learning (ML) and artificial intelligence (AI)
technologies are playing an increasingly critical role in the new era of
precision psychiatry. Combining ML/AI with neuromodulation technologies can
potentially provide explainable solutions in clinical practice and effective
therapeutic treatment. Advanced wearable and mobile technologies also call for
the new role of ML/AI for digital phenotyping in mobile mental health. In this
review, we provide a comprehensive review of the ML methodologies and
applications by combining neuroimaging, neuromodulation, and advanced mobile
technologies in psychiatry practice. Additionally, we review the role of ML in
molecular phenotyping and cross-species biomarker identification in precision
psychiatry. We further discuss explainable AI (XAI) and causality testing in a
closed-human-in-the-loop manner, and highlight the ML potential in multimedia
information extraction and multimodal data fusion. Finally, we discuss
conceptual and practical challenges in precision psychiatry and highlight ML
opportunities in future research
Computational Approaches to Explainable Artificial Intelligence:Advances in Theory, Applications and Trends
Deep Learning (DL), a groundbreaking branch of Machine Learning (ML), has emerged as a driving force in both theoretical and applied Artificial Intelligence (AI). DL algorithms, rooted in complex and non-linear artificial neural systems, excel at extracting high-level features from data. DL has demonstrated human-level performance in real-world tasks, including clinical diagnostics, and has unlocked solutions to previously intractable problems in virtual agent design, robotics, genomics, neuroimaging, computer vision, and industrial automation. In this paper, the most relevant advances from the last few years in Artificial Intelligence (AI) and several applications to neuroscience, neuroimaging, computer vision, and robotics are presented, reviewed and discussed. In this way, we summarize the state-of-the-art in AI methods, models and applications within a collection of works presented at the 9 International Conference on the Interplay between Natural and Artificial Computation (IWINAC). The works presented in this paper are excellent examples of new scientific discoveries made in laboratories that have successfully transitioned to real-life applications
Low-Cost Sensors and Biological Signals
Many sensors are currently available at prices lower than USD 100 and cover a wide range of biological signals: motion, muscle activity, heart rate, etc. Such low-cost sensors have metrological features allowing them to be used in everyday life and clinical applications, where gold-standard material is both too expensive and time-consuming to be used. The selected papers present current applications of low-cost sensors in domains such as physiotherapy, rehabilitation, and affective technologies. The results cover various aspects of low-cost sensor technology from hardware design to software optimization
- …