155 research outputs found
Continuous Rationale Management
Continuous Software Engineering (CSE) is a software life cycle model open to frequent changes in requirements or technology. During CSE, software developers continuously make decisions on the requirements and design of the software or the development process. They establish essential decision knowledge, which they need to document and share so that it supports the evolution and changes of the software. The management of decision knowledge is called rationale management. Rationale management provides an opportunity to support the change process during CSE.
However, rationale management is not well integrated into CSE. The overall goal of this dissertation is to provide workflows and tool support for continuous rationale management. The dissertation contributes an interview study with practitioners from the industry, which investigates rationale management problems, current practices, and features to support continuous rationale management beneficial for practitioners. Problems of rationale management in practice are threefold:
First, documenting decision knowledge is intrusive in the development process and an additional effort.
Second, the high amount of distributed decision knowledge documentation is difficult to access and use.
Third, the documented knowledge can be of low quality, e.g., outdated, which impedes its use.
The dissertation contributes a systematic mapping study on recommendation and classification approaches to treat the rationale management problems.
The major contribution of this dissertation is a validated approach for continuous rationale management consisting of the ConRat life cycle model extension and the comprehensive ConDec tool support. To reduce intrusiveness and additional effort, ConRat integrates rationale management activities into existing workflows, such as requirements elicitation, development, and meetings. ConDec integrates into standard development tools instead of providing a separate tool. ConDec enables lightweight capturing and use of decision knowledge from various artifacts and reduces the developers' effort through automatic text classification, recommendation, and nudging mechanisms for rationale management. To enable access and use of distributed decision knowledge documentation, ConRat defines a knowledge model of decision knowledge and other artifacts. ConDec instantiates the model as a knowledge graph and offers interactive knowledge views with useful tailoring, e.g., transitive linking. To operationalize high quality, ConRat introduces the rationale backlog, the definition of done for knowledge documentation, and metrics for intra-rationale completeness and decision coverage of requirements and code. ConDec implements these agile concepts for rationale management and a knowledge dashboard. ConDec also supports consistent changes through change impact analysis.
The dissertation shows the feasibility, effectiveness, and user acceptance of ConRat and ConDec in six case study projects in an industrial setting. Besides, it comprehensively analyses the rationale documentation created in the projects. The validation indicates that ConRat and ConDec benefit CSE projects. Based on the dissertation, continuous rationale management should become a standard part of CSE, like automated testing or continuous integration
Multiparametric Magnetic Resonance Imaging Artificial Intelligence Pipeline for Oropharyngeal Cancer Radiotherapy Treatment Guidance
Oropharyngeal cancer (OPC) is a widespread disease and one of the few domestic cancers that is rising in incidence. Radiographic images are crucial for assessment of OPC and aid in radiotherapy (RT) treatment. However, RT planning with conventional imaging approaches requires operator-dependent tumor segmentation, which is the primary source of treatment error. Further, OPC expresses differential tumor/node mid-RT response (rapid response) rates, resulting in significant differences between planned and delivered RT dose. Finally, clinical outcomes for OPC patients can also be variable, which warrants the investigation of prognostic models. Multiparametric MRI (mpMRI) techniques that incorporate simultaneous anatomical and functional information coupled to artificial intelligence (AI) approaches could improve clinical decision support for OPC by providing immediately actionable clinical rationale for adaptive RT planning. If tumors could be reproducibly segmented, rapid response could be classified, and prognosis could be reliably determined, overall patient outcomes would be optimized to improve the therapeutic index as a function of more risk-adapted RT volumes. Consequently, there is an unmet need for automated and reproducible imaging which can simultaneously segment tumors and provide predictive value for actionable RT adaptation. This dissertation primarily seeks to explore and optimize image processing, tumor segmentation, and patient outcomes in OPC through a combination of advanced imaging techniques and AI algorithms.
In the first specific aim of this dissertation, we develop and evaluate mpMRI pre-processing techniques for use in downstream segmentation, response prediction, and outcome prediction pipelines. Various MRI intensity standardization and registration approaches were systematically compared and benchmarked. Moreover, synthetic image algorithms were developed to decrease MRI scan time in an effort to optimize our AI pipelines. We demonstrated that proper intensity standardization and image registration can improve mpMRI quality for use in AI algorithms, and developed a novel method to decrease mpMRI acquisition time.
Subsequently, in the second specific aim of this dissertation, we investigated underlying questions regarding the implementation of RT-related auto-segmentation. Firstly, we quantified interobserver variability for an unprecedented large number of observers for various radiotherapy structures in several disease sites (with a particular emphasis on OPC) using a novel crowdsourcing platform. We then trained an AI algorithm on a series of extant matched mpMRI datasets to segment OPC primary tumors. Moreover, we validated and compared our best model\u27s performance to clinical expert observers. We demonstrated that AI-based mpMRI OPC tumor auto-segmentation offers decreased variability and comparable accuracy to clinical experts, and certain mpMRI input channel combinations could further improve performance.
Finally, in the third specific aim of this dissertation, we predicted OPC primary tumor mid-therapy (rapid) treatment response and prognostic outcomes. Using co-registered pre-therapy and mid-therapy primary tumor manual segmentations of OPC patients, we generated and characterized treatment sensitive and treatment resistant pre-RT sub-volumes. These sub-volumes were used to train an AI algorithm to predict individual voxel-wise treatment resistance. Additionally, we developed an AI algorithm to predict OPC patient progression free survival using pre-therapy imaging from an international data science competition (ranking 1st place), and then translated these approaches to mpMRI data. We demonstrated AI models could be used to predict rapid response and prognostic outcomes using pre-therapy imaging, which could help guide treatment adaptation, though further work is needed.
In summary, the completion of these aims facilitates the development of an image-guided fully automated OPC clinical decision support tool. The resultant deliverables from this project will positively impact patients by enabling optimized therapeutic interventions in OPC. Future work should consider investigating additional imaging timepoints, imaging modalities, uncertainty quantification, perceptual and ethical considerations, and prospective studies for eventual clinical implementation. A dynamic version of this dissertation is publicly available and assigned a digital object identifier through Figshare (doi: 10.6084/m9.figshare.22141871)
Modelling, Dimensioning and Optimization of 5G Communication Networks, Resources and Services
This reprint aims to collect state-of-the-art research contributions that address challenges in the emerging 5G networks design, dimensioning and optimization. Designing, dimensioning and optimization of communication networks resources and services have been an inseparable part of telecom network development. The latter must convey a large volume of traffic, providing service to traffic streams with highly differentiated requirements in terms of bit-rate and service time, required quality of service and quality of experience parameters. Such a communication infrastructure presents many important challenges, such as the study of necessary multi-layer cooperation, new protocols, performance evaluation of different network parts, low layer network design, network management and security issues, and new technologies in general, which will be discussed in this book
Proc. 33. Workshop Computational Intelligence, Berlin, 23.-24.11.2023
Dieser Tagungsband enthält die Beiträge des 33. Workshops „Computational Intelligence“ der vom 23.11. – 24.11.2023 in Berlin stattfindet. Die Schwerpunkte sind Methoden, Anwendungen und Tools für ° Fuzzy-Systeme, ° Künstliche Neuronale Netze, ° Evolutionäre Algorithmen und ° Data-Mining-Verfahren sowie der Methodenvergleich anhand von industriellen und Benchmark-Problemen.The workshop proceedings contain the contributions of the 33rd workshop "Computational Intelligence" which will take place from 23.11. - 24.11.2023 in Berlin. The focus is on methods, applications and tools for ° Fuzzy systems, ° Artificial Neural Networks, ° Evolutionary algorithms and ° Data mining methods as well as the comparison of methods on the basis of industrial and benchmark problems
Novel deep learning architectures for marine and aquaculture applications
Alzayat Saleh's research was in the area of artificial intelligence and machine learning to autonomously recognise fish and their morphological features from digital images. Here he created new deep learning architectures that solved various computer vision problems specific to the marine and aquaculture context. He found that these techniques can facilitate aquaculture management and environmental protection. Fisheries and conservation agencies can use his results for better monitoring strategies and sustainable fishing practices
Scholarly Communication Librarianship and Open Knowledge
The intersection of scholarly communication librarianship and open education offers a unique opportunity to expand knowledge of scholarly communication topics in both education and practice. Open resources can address the gap in teaching timely and critical scholarly communication topics—copyright in teaching and research environments, academic publishing, emerging modes of scholarship, impact measurement—while increasing access to resources and equitable participation in education and scholarly communication.
Scholarly Communication Librarianship and Open Knowledge is an open textbook and practitioner’s guide that collects theory, practice, and case studies from nearly 80 experts in scholarly communication and open education. Divided into three parts:
*What is Scholarly Communication?
*Scholarly Communication and Open Culture
*Voices from the Field: Perspectives, Intersections, and Case Studies
The book delves into the economic, social, policy, and legal aspects of scholarly communication as well as open access, open data, open education, and open science and infrastructure. Practitioners provide insight into the relationship between university presses and academic libraries, defining collection development as operational scholarly communication, and promotion and tenure and the challenge for open access.
Scholarly Communication Librarianship and Open Knowledge is a thorough guide meant to increase instruction on scholarly communication and open education issues and practices so library workers can continue to meet the changing needs of students and faculty. It is also a political statement about the future to which we aspire and a challenge to the industrial, commercial, capitalistic tendencies encroaching on higher education. Students, readers, educators, and adaptors of this resource can find and embrace these themes throughout the text and embody them in their work
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