Foreword Identification and Control in Biomedical Applications

Control engineering (in the broad sense of the term) has become an important enabling technology in many areas of medicine. Prominent examples include the artificial pancreas, closed-loop anesthesia, and personalized drug dosing strategies in neurology, oncology, endocrinology, and psychiatry. It is a testament to the power of control systems that allow individualizing treatment by providing mechanisms for linking treatment goals to treatment regimens, thus achieving a desired therapeutic effect. Consequently, the arrival of control systems engineering to the clinic enables the visionary concept of "treat the patient, not the disease" technologically and economically feasible

Guest editorial foreword to the special issue on intelligent computation for bioinformatics

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Trumping communitarianism: crime control and forensic DNA typing and databasing in Singapore

Liberalism and communitarianism have figured prominently in discussions of how to govern forensic DNA practices (forensic DNA typing and databasing). Despite the prominence of these two political philosophies and their underlying values, no studies have looked at the governance of forensic DNA practices in a nondemocratic country governed by a communitarian logic. To fill this lacuna in the literature, this article considers Singapore as an authoritarian state governed by a communitarian philosophy. The article highlights basic innovations and technologies of forensic DNA practices and articulates a liberal democratic version of “biolegality” as described by Michael Lynch and Ruth McNally. It goes on to consider briefly various (political) philosophies (liberalism and communitarianism) and law enforcement models (due process and crime control models). The main part of the article records the trajectory, and hence biolegal progress, of forensic DNA practices in Singapore and compares it with trajectories in England and the United States. The article concludes that Singapore's forensic DNA practices are organized according to the crime control model and therefore safety and the war against crime and terrorism trump individual rights and legal principles such as privacy, bodily integrity, proportionality, presumption of innocence. and onus of proof

Starting from scratch: patient-reported outcome questionnaires & their role in an integrative medicine primary care minimum-dataset

Aim This research explored the use of patient questionnaires for evaluating integrative medicine (IM) clinics in the primary care setting. Background Integrative medicine (IM) combines traditional, complementary, and alternative medicine with conventional biomedicine. With more clinics in Australia offering IM, it is important to evaluate outcomes. Methods Mixed methods were used. This included a case study of an IM clinic in Sydney, Australia; interviews with 20 patients and 13 staff at the clinic; and a systematic literature review of patient questionnaires. Results Challenges for meausring IM outcomes limitations with routine clinical data collection, selecting appropriate questionnaires able to measure the wide range of IM outcomes whilst minimizing responder burden, patient recruitment and practitioner support. Electronic questionnaires have many advantages. Alternative formats such as paper are still needed. Not all interviewees were interested in cohort results or research and instead wanted to access their individual patient results. Discussion The results from the studies were synthesised and a set of recommendations are offered. Conclusions Patient questionnaires could be used to establish a minimum dataset for use in research, health service development, and informing and improving individual patient care. A bottom-up approach that adresses stakeholders’ needs for a dataset is essential

Ono: an open platform for social robotics

In recent times, the focal point of research in robotics has shifted from industrial ro- bots toward robots that interact with humans in an intuitive and safe manner. This evolution has resulted in the subfield of social robotics, which pertains to robots that function in a human environment and that can communicate with humans in an int- uitive way, e.g. with facial expressions. Social robots have the potential to impact many different aspects of our lives, but one particularly promising application is the use of robots in therapy, such as the treatment of children with autism. Unfortunately, many of the existing social robots are neither suited for practical use in therapy nor for large scale studies, mainly because they are expensive, one-of-a-kind robots that are hard to modify to suit a specific need. We created Ono, a social robotics platform, to tackle these issues. Ono is composed entirely from off-the-shelf components and cheap materials, and can be built at a local FabLab at the fraction of the cost of other robots. Ono is also entirely open source and the modular design further encourages modification and reuse of parts of the platform