35,584 research outputs found
Issues in the Design of a Pilot Concept-Based Query Interface for the Neuroinformatics Information Framework
This paper describes a pilot query interface that has been constructed to help us explore a "concept-based" approach for searching the
Neuroscience Information Framework (NIF). The query interface is
concept-based in the sense that the search terms submitted through the
interface are selected from a standardized vocabulary of terms
(concepts) that are structured in the form of an ontology. The NIF
contains three primary resources: the NIF Resource Registry, the NIF
Document Archive, and the NIF Database Mediator. These NIF resources
are very different in their nature and therefore pose challenges when
designing a single interface from which searches can be automatically
launched against all three resources simultaneously. The paper first
discusses briefly several background issues involving the use of
standardized biomedical vocabularies in biomedical information
retrieval, and then presents a detailed example that illustrates how
the pilot concept-based query interface operates. The paper concludes
by discussing certain lessons learned in the development of the current
version of the interface
Chemoinformatics Research at the University of Sheffield: A History and Citation Analysis
This paper reviews the work of the Chemoinformatics Research Group in the Department of Information Studies at the University of Sheffield, focusing particularly on the work carried out in the period 1985-2002. Four major research areas are discussed, these involving the development of methods for: substructure searching in databases of three-dimensional structures, including both rigid and flexible molecules; the representation and searching of the Markush structures that occur in chemical patents; similarity searching in databases of both two-dimensional and three-dimensional structures; and compound selection and the design of combinatorial libraries. An analysis of citations to 321 publications from the Group shows that it attracted a total of 3725 residual citations during the period 1980-2002. These citations appeared in 411 different journals, and involved 910 different citing organizations from 54 different countries, thus demonstrating the widespread impact of the Group's work
Improving Knowledge Retrieval in Digital Libraries Applying Intelligent Techniques
Nowadays an enormous quantity of heterogeneous and distributed information is stored in the digital University. Exploring online collections to find knowledge relevant to a user’s interests is a challenging work. The artificial intelligence and Semantic Web provide a common framework that allows knowledge to
be shared and reused in an efficient way. In this work we propose a comprehensive approach for discovering E-learning objects in large digital collections based on analysis of recorded semantic metadata in those objects and the application of expert system technologies. We have used Case Based-Reasoning
methodology to develop a prototype for supporting efficient retrieval knowledge from online repositories.
We suggest a conceptual architecture for a semantic search engine. OntoUS is a collaborative effort that
proposes a new form of interaction between users and digital libraries, where the latter are adapted to users
and their surroundings
Utilizing RxNorm to Support Practical Computing Applications: Capturing Medication History in Live Electronic Health Records
RxNorm was utilized as the basis for direct-capture of medication history
data in a live EHR system deployed in a large, multi-state outpatient
behavioral healthcare provider in the United States serving over 75,000
distinct patients each year across 130 clinical locations. This tool
incorporated auto-complete search functionality for medications and proper
dosage identification assistance. The overarching goal was to understand if and
how standardized terminologies like RxNorm can be used to support practical
computing applications in live EHR systems. We describe the stages of
implementation, approaches used to adapt RxNorm's data structure for the
intended EHR application, and the challenges faced. We evaluate the
implementation using a four-factor framework addressing flexibility, speed,
data integrity, and medication coverage. RxNorm proved to be functional for the
intended application, given appropriate adaptations to address high-speed
input/output (I/O) requirements of a live EHR and the flexibility required for
data entry in multiple potential clinical scenarios. Future research around
search optimization for medication entry, user profiling, and linking RxNorm to
drug classification schemes holds great potential for improving the user
experience and utility of medication data in EHRs.Comment: Appendix (including SQL/DDL Code) available by author request.
Keywords: RxNorm; Electronic Health Record; Medication History;
Interoperability; Unified Medical Language System; Search Optimizatio
The SP theory of intelligence: benefits and applications
This article describes existing and expected benefits of the "SP theory of
intelligence", and some potential applications. The theory aims to simplify and
integrate ideas across artificial intelligence, mainstream computing, and human
perception and cognition, with information compression as a unifying theme. It
combines conceptual simplicity with descriptive and explanatory power across
several areas of computing and cognition. In the "SP machine" -- an expression
of the SP theory which is currently realized in the form of a computer model --
there is potential for an overall simplification of computing systems,
including software. The SP theory promises deeper insights and better solutions
in several areas of application including, most notably, unsupervised learning,
natural language processing, autonomous robots, computer vision, intelligent
databases, software engineering, information compression, medical diagnosis and
big data. There is also potential in areas such as the semantic web,
bioinformatics, structuring of documents, the detection of computer viruses,
data fusion, new kinds of computer, and the development of scientific theories.
The theory promises seamless integration of structures and functions within and
between different areas of application. The potential value, worldwide, of
these benefits and applications is at least $190 billion each year. Further
development would be facilitated by the creation of a high-parallel,
open-source version of the SP machine, available to researchers everywhere.Comment: arXiv admin note: substantial text overlap with arXiv:1212.022
Thesauri on the Web: current developments and trends
This article provides an overview of recent developments relating to the application of thesauri in information organisation and retrieval on the World Wide Web. It describes some recent thesaurus projects undertaken to facilitate resource description and discovery and access to wide-ranging information resources on the Internet. Types of thesauri available on the Web, thesauri integrated in databases and information retrieval systems, and multiple-thesaurus systems for cross-database searching are also discussed. Collective efforts and events in addressing the standardisation and novel applications of thesauri are briefly reviewed
Living with the Semantic Gap: Experiences and remedies in the context of medical imaging
Semantic annotation of images is a key concern for the newly emerged applications of semantic multimedia. Machine processable descriptions of images make it possible to automate a variety of tasks from search and discovery to composition and collage of image data bases. However, the ever occurring problem of the semantic gap between the low level descriptors and the high level interpretation of an image poses new challenges and needs to be addressed before the full potential of semantic multimedia can be realised. We explore the possibilities and lessons learnt with applied semantic multimedia from our engagement with medical imaging where we deployed ontologies and a novel distributed architecture to provide semantic annotation, decision support and methods for tackling the semantic gap problem
Natural language processing
Beginning with the basic issues of NLP, this chapter aims to chart the major research activities in this area since the last ARIST Chapter in 1996 (Haas, 1996), including: (i) natural language text processing systems - text summarization, information extraction, information retrieval, etc., including domain-specific applications; (ii) natural language interfaces; (iii) NLP in the context of www and digital libraries ; and (iv) evaluation of NLP systems
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