1,880 research outputs found
A High-Order Kernel Method for Diffusion and Reaction-Diffusion Equations on Surfaces
In this paper we present a high-order kernel method for numerically solving
diffusion and reaction-diffusion partial differential equations (PDEs) on
smooth, closed surfaces embedded in . For two-dimensional
surfaces embedded in , these types of problems have received
growing interest in biology, chemistry, and computer graphics to model such
things as diffusion of chemicals on biological cells or membranes, pattern
formations in biology, nonlinear chemical oscillators in excitable media, and
texture mappings. Our kernel method is based on radial basis functions (RBFs)
and uses a semi-discrete approach (or the method-of-lines) in which the surface
derivative operators that appear in the PDEs are approximated using
collocation. The method only requires nodes at "scattered" locations on the
surface and the corresponding normal vectors to the surface. Additionally, it
does not rely on any surface-based metrics and avoids any intrinsic coordinate
systems, and thus does not suffer from any coordinate distortions or
singularities. We provide error estimates for the kernel-based approximate
surface derivative operators and numerically study the accuracy and stability
of the method. Applications to different non-linear systems of PDEs that arise
in biology and chemistry are also presented
Interpretable statistics for complex modelling: quantile and topological learning
As the complexity of our data increased exponentially in the last decades, so has our
need for interpretable features. This thesis revolves around two paradigms to approach
this quest for insights.
In the first part we focus on parametric models, where the problem of interpretability
can be seen as a “parametrization selection”. We introduce a quantile-centric
parametrization and we show the advantages of our proposal in the context of regression,
where it allows to bridge the gap between classical generalized linear (mixed)
models and increasingly popular quantile methods.
The second part of the thesis, concerned with topological learning, tackles the
problem from a non-parametric perspective. As topology can be thought of as a way
of characterizing data in terms of their connectivity structure, it allows to represent
complex and possibly high dimensional through few features, such as the number of
connected components, loops and voids. We illustrate how the emerging branch of
statistics devoted to recovering topological structures in the data, Topological Data
Analysis, can be exploited both for exploratory and inferential purposes with a special
emphasis on kernels that preserve the topological information in the data.
Finally, we show with an application how these two approaches can borrow strength
from one another in the identification and description of brain activity through fMRI
data from the ABIDE project
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